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Biomedical subjects

O Tochikubo

Publications and source records attributed to O Tochikubo.

112 records · Page 7Linked to original sources
PubMedDate not supplied

Simple portable device for sampling a whole day's urine and its application to hypertensive outpatients.

To simplify 24-hour urine collection for epidemiological and clinical examinations, we devised a portable, semiautomatic urine sampling cup with divided partitions. The cup, 6.6 cm in diameter and 14 cm in height, is double-bottomed and has a pipe-shaped scale and a cock leading to the lower compartment. It is so devised that 1/m of the urine volume excreted into the upper compartment each time remains in the pipe scale, and then comes down into the lower compartment by manipulating the cock. The urine in the lower compartment remains when the urine in the upper compartment is discarded. The cup is carried in a vinyl bag. By repeating this manipulation. 1/m of the total urine excreted during 24 hours can be collected in the small cup (proportional sampling method). When the 24-hour urinary sodium excretion measured by the conventional method and that measured by this method were compared, the correlation coefficient (r) was 0.98, and the average variation was 2.0 +/- 10.8 (SD) mEq (n = 32). Use of this device for outpatients was convenient and enabled counseling on salt intake.

Ambulatory Care↗
PubMedDate not supplied

Reduced arterial baroreflex control of muscle sympathetic nerve activity in young borderline hypertensives.

Mean arterial pressure (MAP), heart interval (HI) and muscle sympathetic nerve activity (MSNA) were measured before and after a bolus injection of phenylephrine in 11 normotensives (NT) and 12 borderline hypertensives (BHT). (1) Basal MSNA was elevated in BHT compared to NT. (2) Both baroreflex slope for HI and that for MSNA were significantly less in BHT. (3) There was an inverse correlation between the slope for MSNA and the basal MSNA (r = -0.63). Thus, arterial baroreflex control of sympathetic activity may be reduced in BHT and the reduction may be involved in the elevated sympathetic nerve activity in these subjects.

Adult↗