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Biomedical subjects

O Thetter

Publications and source records attributed to O Thetter.

At least 91 records · Page 5Linked to original sources
PubMed1986

[Incidence of stab injuries of the heart in the clinic and forensic autopsy practice. Experiences with 6 surgical procedures].

During a period when 6 patients were operated following a cardiac stab wound 4 patients survived the procedure. In 45 persons forensic autopsies were performed. The analysis of both groups elucidate that successful treatment is possible if pericardial tamponade inhibits free bleeding into the cavity of the thorax. But this situation must be treated very quickly avoiding cardiac arrest due to cardial blockage. In contrast to the autopsies in the clinical group no atrial wounds or incisions of coronary arteries were observed.

Adolescent↗
PubMed1985

[Neurofibromatosis and the development of neurofibrosarcoma simulating Baker's cyst].

A 39-year-old female patient with familiar neurofibromatosis developed a sarcoma in the hollow of the knee that appeared clinically and sonographically as a Baker cyst. Following an operation to remove the tumour and subsequent local radiation treatment multiple metastases appeared distant to the primary tumour from which the patient died. On the observation of a Baker cyst in a patient with neurofibromatosis the possibility of malignant degeneration must be kept in mind and an operation carried out immediately.

Adult↗
PubMed1985

[The thoracic outlet compression syndrome and its vascular complications].

The costoclavicular compression syndrome and the cervical rib syndrome can cause arterial complications of the subclavian artery: mural thrombosis, occlusion and aneurysma. These complications can result in peripheral emboli or cerebrovascular insufficiency. Such sequelae can be avoided by timely surgical treatment of these compression syndromes. The therapy of choice is transaxillary rib resection. The same axillary approach can also be used for directly reconstructing the subclavian artery.

Aneurysm↗
PubMed1984

[Sexual function after vascular surgical interventions in the aortoiliac area--causes and the avoidance of impotence].

Neurogenic and vasculogenic impotence after aortoiliac reconstruction is an unpleasant problem in vascular surgery. The importance of maintaining or restoring intraoperatively a sufficient hypogastric artery blood flow is emphasized. Postoperative neurogenic sexual disabilities are irreversible and are due to interruption of sympathetic nerve fibers supplying the genital system. Dissecting the terminal aorta and the iliac arteries the hypogastric sympathetic plexus--which descends across the bifurcation--can be easily damaged. This is the cause of the high incidence of failure of ejaculation after aortoiliac surgery. In order to avoid this neurogenic sexual dysfunction a retromesenteric approach to the aortoiliac region is anatomically suggested by A. v. Hochstetter. It enables the exposure of the abdominal aorta and the iliac arteries without disrupting the superior hypogastric plexus and its variants. Respecting the integrity of the sympathetic plexus and a sufficient flow in the internal iliac artery the frequency of postoperative disturbances of erection was reduced from 17% (1199 patients) to 12.3% (570 patients). The incidence of postoperative loss of ejaculation in the same groups of patients decreased from 81% to 20%.

Aorta, Abdominal↗
PubMed1984

[Infrared coagulation of the lung. Initial experimental and clinical results].

With regard to the good results which were found using the infrared coagulator (IRC) in hemostasis of liver and spleen experimental and clinical investigations of the lung were performed. Animal experiments elucidated the necessity of ligation of greater vessels as well as bronchi. Secure plugging of lung tissue was also possible following increased positive pressure respiration. A mean maximal extend of necrosis of 3 mm was measured. Clinical use in 11 patients proved secure plugging of tissue due to IRC application. Drainages could be removed within 4 days without appearance of broncho-pleural fistulas.

Adult↗
PubMed1981

Fibrin adhesive and its application in thoracic surgery.

Human fibrinogen cryoprecipitate has found wide application as a biologic tissue adhesive in thoracic and cardiovascular surgery. During 1979 and 1980 fibrin adhesive was applied in all surgical procedures involving persistent or recurrent pneumothorax and it was used prophylactically to cover large parenchymal defects following standard lung resections. The benefit of its application on pleura and lung tissue derives from added reinforcement of sutures and sealing of non-saturable defects. Twenty-one patients with recurrent spontaneous pneumothorax revealed a reduced average drainage period as compared to 15 non-glued cases with lesions of comparable size. Similarly, in 20 cases where tissue adhesive was applied to extensive pleural defects following segmental lung resection or lobectomy, suction drainage time was significantly less than in 11 cases of comparable, non-glued defects. Compared to 140 lung resections performed prior to the use of fibrin glue, these 20 cases were found to require the same average drainage time, although the extent of their lesions would otherwise have warranted longer periods of continued suction drainage.

Adult↗
PubMed1980

[Concept of therapy in gunshot wounds].

174 patients with civilian gunshot wounds are presented. A staged approach with early debridement, followed by reparative and reconstructive procedures with delayed primary closure is advocated. Immediate laparotomy must be performed, if there is suspicion of perforation. Allowing for exceptions early thoracotomy cannot be regarded as an urgent indication.

Adolescent↗
PubMed1978

[The influence of pretreatment with specific antibodies on Renal Xenograft Rejection (author's transl)].

26 pig kidneys were perfused in a "Gambro" kidney perfusion machine. The perfusates used were unmodified canine plasma and serum, as well as complement-free plasma, gamma-globulin solutions obtained from dogs immunized against pig leucocytes (ALG) and 2-mercapto-ethanol treated ALG (2 ME-ALG). The typical pig-to-dog xenograft rejection was reproduced by ex vivo perfusion with native dog plasma and serum. Using complement-free dog plasma, ALG and 2 ME-ALG pig kidneys could be perfused for several hours without significant increase in perfusion resistance. 22 pig kidneys, pretreated by perfusion for 2 hours with complement-free dog plasma, ALG and 2 ME-ALG, were transplanted on to the vessels of the neck of recipient dogs. Grafts pretreated with decomplemented dog plasma and 2 ME-ALG were rejected in the usual fashion within 5 to 20 min. Pretreatment with ALG resulted in a prolongation of graft function for 80 to 100 min. It is suggested that ALG exerted a transient blocking effect on the cytotoxic action of recipient IgM resembling passive enhancement; this phenomenon may be limited to sites with low antigen density, corresponding to in vitro findings of passive enhancement on cells with low surface antigen density.

Animals↗
PubMed1976

[Concentration course of Na-Penicillin G in wound secretions following vascular surgery].

After infusion of 10 and 20 M.I.U. of Na-penicilline G, the concentrations in serum, wound exudation, and urine were analysed, at equal points of time, following vascular reconstruction; pharmacokinetic data were calculated as well. The importance of local concentration of antibiotics for therapy and prevention of infections is emphasized - according to pharmacokinetics - in relation to the blood level. Simultaneously, the influence of pathological changes is discussed and represented by a brief case follow-up.

Aged↗