Biomedical subjects

O Székely

Publications and source records attributed to O Székely.

10 recordsLinked to original sources

PubMed1977

[Changes in the granula of type II pneumocytes corresponding to the oxygen content of the air].

The morphology of granula of type II-granulocytes from lungs of rabbits and rats was studied. In pneumocytes of rabbits dense bodies predominated with high lipoprotein content, whereas in rats the majority had lamellar structure. Under treatment with hyperbaric oxygen the granula showed increased lipoprotein content, suggesting that the emanation of the content of granula to the alveolar surface is inhibited. Under hypoxia the release from the granula was enhanced, and after 16 hours of hypoxia the amount of granula was decreased as well as their lipoprotein content.

Animals↗

PubMed1977

Intramitochondrial calcification and myocardial inclusions in the rabbit due to anoxic hypoxia.

Intramitochondrial calcium granules and calcification of the mitochondrial cristae were examined in myocardial cells of rabbits in acute anoxic hypoxia, under normal circulation. The alterations were noted first after 2 hours of hypoxia, and became progressively larger and more ubiquitous with increasing periods of anoxic hypoxia. After 8 hours or longer hypoxia intramitochondrial "cristalloids" were found in some mitochondria.

Acute Disease↗

PubMed1976

Histochemical and ultrastructural alterations of the duodenum in acute hypoxia.

Laboratory animals were kept for 2, 8 and 16 hours in a pressure chamber, the air of which contained 8% O2 and 92% N2. Histochemical and ultrastructural examinations revealed the following duodenal alterations: 1. The alkaline phosphatase activity of the epithelium and glandular epithelium showed no alteration; the acid phosphatase activity was slightly increased in hypoxia. 2. The succinic dehydrogenase and cytochrome C oxidase activities of the glandular epithelium showed a marked decrease. 3. Two hours of hypoxia led to destruction of the microvillous epithelium. Prolonged hypoxia resulted in the destruction of the microvilli as well as of the cuticula. 4. Hypoxia of short duration had no damaging effect on glandular epithelial cells. After 8 to 16 hours of hypoxia, glandular secretion was reduced and the epithelial cells were evacuated. From the findings of the present investigation it is concluded that the decrease in the production of protective intestinal juice, due to the damaging effect of hypoxia on the epithelium and glandular epithelium as well as on the mitochondria, and the increase in the absorption of the intestinal content should be considered responsible of the additional damages to the intestinal epithelium.

Acid Phosphatase↗

PubMed1973