The biological role of the cortisol binding globulin (C.B.G.) in plasma.
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Biomedical subjects
Publications and source records attributed to O Steeno.
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Gamma-glutamyltranspeptidase activity and fructose concentration have been measured in 100 semen samples, in 7 split ejaculates and in the seminal fluid of a patient with congenital absence of ductus deferens and seminal vesicles. Evidence is presented that the prostate is the major source of gamma-glutamyltranspeptidase in human semen.
In this study clinical, andrological and endocrinological data of a group of 101 patients with ejaculate volume of at least 8.0 ml are compared with data of 100 consecutive patients attending our infertility clinic. Within both groups correlations between different parameters are observed. Between both groups a significant difference in total sperm output is noted suggesting a 'dilution oligozoospermia' in the high ejaculate volume group. We suggest that, in order to avoid a falsely unfavourable fertility prognosis for those patients, total sperm output should be considered rather than sperm density. From the point of view of nomenclature, the term 'relative oligozoospermia' seems justified in cases with very high ejaculate volumes.
This study examined the seasonal variation in three semen parameters (total sperm count, % grade a progressive motility and sperm morphology according to strict criteria) with an identical abstinence period of 24 h. A total of 340 spermiograms of 107 different men enrolled in an intrauterine insemination (IUI) program were examined. To reduce variation due to interindividual disparities in semen quality, differences of each test result from the mean value obtained for that individual were analyzed. Mean values resulted from at least 3 observations during different IUI cycles. Using ANOVA and spectral analysis, no differences in semen parameter results in function of the month of the year were observed. The lack of any significant periodicity may be explained by the large biological variation for individual semen parameters and/or the lack of significant differences regarding light exposure and temperature between summer and winter months in moderate climates.
Because of the present tendency to operate early on undescended testes, the indication for orchidopexy amounts to six-to-seven times the justified number in the Netherlands and two-to-three times in Flanders! The tendency to operate early has surely caused more fertility damage than prevented it. This critical statement asks for consideration and urges everybody concerned to a more accurate and repeated physical examination of the genital region and to a conservative attitude regarding treatment.
In connection with a case-study we go further into the subject of a subcutaneous injection of fysostigmine as an alternative way to obtain an ejaculation with men suffering a cross-lesion but still wishing to have children.
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