[1-alpha-hydroxycholecalciferol. Treatment of patients with chronic renal insufficiency requiring dialysi].
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Humans↗
Biomedical subjects
O Schaadt
Publications and source records attributed to O Schaadt.
Serum ionized calcium in renal failure --- a guideline for 1alpha-hydroxycholecalciferol treatment.
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Blood↗
[The degree of mineralization of bone tissue in chronic uremia compared with radiological, biochemical and clinical findings].
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Adult↗
[Crista biopsy with a new bone biopsy needle].
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Biopsy, Needle↗
The degree of bone mineralization in chronic renal failure estimated from phosphorus/hydroxyproline ratio in bone biopsies.
The degree of bone mineralization is the proportion between the contents of mineral and collagen in bone. As phosphorus (P) and hydroxyproline (Hypro) constitute a constant fraction of bone mineral and collagen, respectively, the P/Hypro ratio in bone tissue provides an estimate of the degree of mineralization. The P/Hydro ratio has been studied in bone biopsies from 42 patients with severe chronic renal failure. A few of them had a subnormal P/Hypro ratio and these patients corresponded to the diagnosis of classical osteomalacia or probably hyperparathyroidism. However, the mean bone P/Hypro ratio was significantly higher than normal, indicating a general tendency towards a higher degree of bone mineralization in patients with chronic renal failure.
Adult↗