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Biomedical subjects

O S Shkrob

Publications and source records attributed to O S Shkrob.

At least 73 records · Page 4Linked to original sources
PubMed1981

[Microbial flora sensitivity to antibacterial agents in chronic pyelonephritis patients who have had acute kidney failure].

The analysis of antibioticograms of patients with a history of chronic pyelonephritis and acute renal insufficiency is presented. It was found that the synergistic effect observed with the use of gentamicin in combination with carbenicillin or ampicillin with cephaloridin provides a decrease in the therapeutic doses of the drugs with a purpose of elimination of their side action.

Acute Kidney Injury↗
PubMed1981

[Diagnosis and treatment of nonpalpable breast tumors].

191 patients with nonpalpable breast tumors were admitted to the Clinic of Surgery of the I. M. Sechenov 1st Medical Institute. The tumors were detected during a mass screening survey; none of the patients had any complaints. Examination and palpation failed to detect any pathologic changes in 60.2% of females, while in 39.8%, bilateral mastopathia cystica was found. All patients underwent sectoral resection with interstitial marking of tumor. The marking procedure is described. Morphological examination confirmed X-ray diagnosis in 83% of cases. Most tumors were localized, while incipient invasive features were revealed in 58.3%. Morphologically, such tumors may be considered early cancer. When diagnosis of malignant tumor was confirmed by histological examination, radical mastectomy after the method of Patey was performed (68.9%). The end results of treatment are presented. Early diagnosis and effective therapy of breast cancer are determined by cooperation of X-ray, surgery and pathology department staff.

Adenofibroma↗
PubMed1980

[Patient survival rate in inoperable stomach cancer].

An analysis of the survival in 361 patients is reported. The kinetics of the survival in these cases is described by an equation of log-normal distribution and quantified by the time of 50% survival. For patients subjected to tentative laparotomy (TL) this time is 4.5 months, for those subjected to gastroenterostomy (GES) -- 6.5 months (the differences being reliable). Patients subjected to TL showed a reliably more frequent combination of such unfavourable prognostic factors as endophytic growth and a large size tumor, proliferation and metastases in the liver and pancreas. Among the patients who were not operated upon, the most low survival rate was noted in cases when surgery was rejected due to evident inoperability. The survival among the subjects inoperated because of general contraindications or patients' refusal is found to be reliably better than in those subjected to TL. It is suggested to ascertain the effect of chemotherapy in inoperable gastric cancer separately in patients subjected to TK, gastroenterostomy and in those without the operation.

Gastroenterostomy↗