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Biomedical subjects

O S Sergel'

Publications and source records attributed to O S Sergel'.

At least 19 recordsLinked to original sources

[The use of the carbon dioxide laser in acute surgical infection of the soft tissues].

Clinico-laboratory studies were conducted in 46 patients with wound infection for the treatment of which carbon-dioxide laser was used, and in 78 patients who were operated on with a metal scalpel (control). It is shown that "excision" and "evaporation" of tissues took 15-45 minutes. Repeated interventions were performed in 15% of cases due to bleeding from vessels measuring 1.0-1.5 mm in diameter. After surgical debridement with a scalpel the number of microbes reduced from 10(7)-10(9) to 10(3)-10(4) per g. After exposure to the laser beam this value was 10(1) but on day 3-4 it was 10(5)-10(6). The extent of the zone of coagulation necrosis in the zone exposed to the laser beams measured up to 500 microns, and began diminishing only on day 7-9 of postoperation. Suppuration of the wounds in 56% of patients of the main group treated by operation was in conformity with the results of bacteriological and morphological studies. In the control group this index was 15.4%. It is concluded that the use of carbon-dioxide laser as a "light scalpel" with subsequent primary closure of the wound is inexpedient. Its use in preparing a wound for closure with secondary sutures has no advantages over radical surgical debridement.

Acute Disease↗

[Quantitative evaluation of humoral and cellular factors of antibacterial protection in patients with postoperative hernia complicated by suppurative process].

The article presents material on the study of the dynamics of humoral factors of the organism's antibacterial protection in correlation with factors of cellular immunity in 78 patients with postoperative ventral hernias complicated by a pyoinflammatory process. Factors of cellular immunity were studied in 33 patients, humoral factors of the organisms' antibacterial protection, in 45 patients. A distinct relation of the character of disorders of these factors to the type of the operation was revealed and their prognostic significance for clinical medicine was determined.

Abdominal Muscles↗

[Morphological and cytological characteristics of the burn healing process by various treatment methods].

Morphological and cytological methods were used to study the healing of a burn wound in local isolation wards (an open treatment method) and under ointment bandages (a closed treatment method). Biopsy specimens and imprints from the burn wound surface were taken from 40 patients. During treatment in an abacterial medium, burn wound was rapidly decontaminated, which was a consequence of the appearance in wound exudate of segmented neutrophils with marked neutrophilic granularity. Granulation tissue was formed in the wound cavity at the 5th-7th day after the treatment commencement. During treatment under bandages wound decontamination was extremely slow. For a long time wound exudate shows the predominance of dystrophically changed neutrophils, while granulation tissue in the wound cavity if formed only at the 21st-24th day after the treatment commencement.

Asepsis↗