Search PubMed⌕ Search

Biomedical subjects

O Ramos

Publications and source records attributed to O Ramos.

31 records · Page 2Linked to original sources
PubMed1986

[Chemical evaluation and determination of the nutritive value of a variety of Opaque-2 corn in the initial diet of broilers].

Chemical and amino acidic composition of Opaque-2 corn, cultivar CIMMYT-TL 81-A (Hungarian compound) locally produced were determined. In addition, the productive performance of broiler chicks fed Opaque-2 corn or normal corn (Pioneer) for the first 28 days of age was evaluated. The chemical and amino acid content results obtained for the Opaque-2 corn studied, compared well ranges previously reported. The productive performance at the end of the experiment was similar between the two treatments assayed.

Amino Acids↗
PubMed1984

[Monozygotic twins with a minimal cerebral dysfunction syndrome].

Two monozygotic boys, 5 years and 5 months old, with a normal IQ, whose father had suffered from stuttering, language retardation and dyslexia showed a minimal brain dysfunction syndrome. A genetic etiology is likely in these patients. Other etiological factors remain obviously possible in other patients.

Attention Deficit Disorder with Hyperactivity↗
PubMed1983

A progressive syndrome of autism, dementia, ataxia, and loss of purposeful hand use in girls: Rett's syndrome: report of 35 cases.

Thirty-five patients, exclusively girls, from three countries had a uniform and striking progressive encephalopathy. After normal general and psychomotor development up to the age of 7 to 18 months, developmental stagnation occurred, followed by rapid deterioration of higher brain functions. Within one-and-a-half years this deterioration led to severe dementia, autism, loss of purposeful use of the hands, jerky truncal ataxia, and acquired microcephaly. The destructive stage was followed by apparent stability lasting through decades. Additional insidious neurological abnormalities supervened, mainly spastic parapareses, vasomotor disturbances of the lower limbs, and epilepsy. Prior extensive laboratory investigations have not revealed the cause. The condition is similar to a virtually overlooked syndrome described by Rett in the German literature. The exclusive involvement of females, correlated with findings in family data analyses, suggests a dominant mutation on one X chromosome that results in affected girls and nonviable male hemizygous conceptuses.

Adolescent↗
PubMed1966

The incidence and prevention of folate deficiency in a pregnant clinic population.

Non-anemic women attending a public antenatal clinic were given, daily, a multivitamin tablet containing 78 mg. of elemental iron. The follow-up studies included an analysis of their diets. A total of 311 patients were included, of which one group received a supplement of 0.5 mg. folic acid and 0.005 mg. vitamin B(12). The incidence of megaloblastic bone marrow change in the unsupplemented group was 26% and of low blood folates approximately 50%. The incidence of megaloblastic changes was sharply reduced in the supplemented group and the blood folates were elevated to supranormal levels, indicating that the dose of folic acid used may have been above the minimal requirement. Formiminoglutamic acid (FIGLU) excretion could not be correlated with other parameters of folate deficiency. Neutrophil lobe counts did not relate to megaloblastic changes or low folate levels unless there was more than 5% hypersegmentation. The dietary intake was suboptimal in total calories, iron and food folate.

Anemia, Macrocytic↗
PubMedDate not supplied

Effects of a specific inhibitor of the vascular action of vasopressin in humans.

Experimental evidence indicates that arginine vasopressin (AVP) may contribute to the rise of blood pressure (BP) in hypertension induced by renal failure and sodium overload. We studied the AVP inhibitor [1-(B-mercapto-B,B-cyclopentamethylenepropionic acid)-2-(O-methyl)tyrosine] AVP in 12 normal and seven hypertensive subjects with end-stage renal disease. To test the agent's capacity to block the pressor action of exogenous AVP In humans, we constructed a dose-response curve with AVP doses of 1 to 20 mU/kg, raising BP by up to 30 mm Hg. Subsequently, five volunteers receive intravenous (i.v.) doses of 0.1 mg, and five volunteers received 0.5 mg of the inhibitor. The dose-response curve was then repeated with AVP doses up to 200 mU/kg. Both doses of the inhibitor shifted the curve to the right and downward, with the BP response to 20 mU/kg AVP being inhibited by 23% and 80% respectively. The duration of action of the compound was tested in two additional subjects, and was found to be over 3 hours. We then tested the compound in seven hypertensive patients with end-stage renal failure. Two days before dialysis, patients received a 150 mEq/day Na diet. After an additional Na load of 180 mEq via i.v. saline over 3 hours under constant BP and ECG monitoring, they received an i.v. bolus of 0.5 mg AVP inhibitor. A moderate BP fall occurred in five patients; it was maximal at 45 to 60 minutes and returned to baseline by 70 to 90 minutes.(ABSTRACT TRUNCATED AT 250 WORDS)

Adult↗
PubMedDate not supplied

Lipoprotein (a) and other risk factors in children with insulin-dependent diabetes mellitus and children without diabetes.

AIMS: To study serum Lp(a) levels and other metabolic cardiovascular risk factors in children with Type 1 diabetes mellitus (DM) compared to sex and age matched nondiabetic children. The correlation of Lp(a) serum levels and other lipid parameters with HbA1c concentrations in diabetic children was investigated. DESIGN: Transversal observational study. TARGET POPULATION: 36 C-peptide negative Type 1 DM children without microalbuminuria and no macromicrovascular or neurological complications, aged 8 to 15 years; 17 boys, 19 girls. Mean duration of Type 1 DM was 4.99 +/- 3.04 years, daily insulin need were 32.79 +/- 12.64 Units. 41 healthy children with no family history of DM, aged from 8 to 15 years, 26 boys, 15 girls, were studied in parallel as the control group. METHODS: Serum total cholesterol (TC) and triglycerides (TG) were assayed by enzymatic methods, high-density lipoprotein (HDL) cholesterol by enzymatic method after precipitation of very-low-density (VLDL) and low-density lipoprotein (LDL) fractions. The LDL fractions was estimated after serum precipitation as the difference between total cholesterol and supernatant cholesterol concentrations. Apo-AI, apo-AII and apo-B were measured by radial immunodiffusion assays. Serum Lp(a) was measured by monoclonal anti-Lp(a) antibody (ELISA) method and whole blood glycosylated hemoglobin A1c (HbA1c) by high resolution liquid chromatography. RESULTS: HbA1c concentration in diabetic children was 7.51 +/- 54% vs 4.16 +/- 0.35% in non diabetic children. Lp(a) serum levels did not significantly differ among both groups (25 +/- 22 mg/dl in diabetics subjects, 22 +/- 22 mg/dl in controls). Significant correlation was found between HbA1c levels and each of TC, LDL and TG serum concentrations in the diabetic group. Lp(a) levels were correlated with glycated hemoglobin in the whole diabetic group. But, in the 2 patients with the poorest metabolic control (HbA1c 10.5%) were excluded, the correlation disappeared. CONCLUSIONS: In 36 children aged 5-15 years with uncomplicated Type 1 DM lasting less than 15 years, Lp(a) serum levels did not differ from age-matched controls but highest Lp(a) values were associated with poorest metabolic control.

Adolescent↗
PubMedDate not supplied

Lipoprotein (a) and other risk factors in children with insulin-dependent diabetes mellitus and children without diabetes.

AIMS: To study serum Lp (a) levels and other metabolic cardiovascular risk factors in children with type 1 diabetes mellitus (DM) as compared to sex and age matched nondiabetic children. The correlation of Lp (a) serum levels and other lipid parameters with HbA1c concentration in diabetic children was investigated. DESIGN: Transversal observational study. TARGET POPULATION: 36 C-peptide negative Type 1 diabetic children without microalbuminuria and no macromicrovascular nor neurological complications, aged 8 to 15 years; 17 boys, 19 girls. Mean duration of Type 1 diabetes was 4.99 +/- 3.04 years, daily insulin needs 32.79 +/- 12.64 Units. 41 healthy children with no family history of diabetes mellitus, aged 8 to 15 years, 26 boys, 15 girls, were studied in parallel as the control group. METHODS: Serum total cholesterol and triglycerides were assayed by enzymatic methods, High-density lipoprotein (HDL) cholesterol by enzymatic method after precipitation of very-low-density (VLDL) and low-density lipoprotein (LDL) fractions. The LDL fraction was estimated after serum precipitation as the difference between total cholesterol and supernatant cholesterol concentrations. Apo-AI, apoA-II and apo-B were measured by radial immunodiffusion assays. Serum Lp(a) was measured by a monoclonal anti-Lp(a) antibody (ELISA) method and whole blood glycosylated hemoglobin A1c (HbA1c) by high resolution liquid chromatography. RESULTS: HbA1c concentration in diabetic children was 7.51 +/- 1.54% vs 4.16 +/- 0.35% in nondiabetic children. Lp(a) serum levels did not significantly differ among both groups (25 +/- 22 mg/dl in diabetics; 22 +/- 22 mg/dl in controls). Significant correlation was found between HbA1c levels and each of TC, LDL and TG serum concentrations in the diabetic group. Lp (a) levels were only correlated with glycated hemoglobin in the two patients showing the highest levels of HbA1c; in the diabetic group: HbA1c 10.9 and 11.5%. CONCLUSIONS: In 36 children aged 8-15 years with uncomplicated Type 1 diabetes for less than 15 years duration, Lp (a) serum levels were positively correlated with HbA1c only in two of them showing the poorest metabolic control.

Adolescent↗
PubMedDate not supplied

Euthanasia and relief of suffering: attitudes of medical students.

Medical students, from the first, second and third year classes of the University of Puerto Rico School of Medicine, answered a questionnaire which included testing knowledge and attitudes about euthanasia and the relief of suffering. More than 60% of each class participated, a total of two hundred. Ninety three percent of the students knew the definition of euthanasia but 50 percent could not tell the difference between active and passive euthanasia. Students in the first year were better oriented than their counterparts in the third year (58 percent versus 44 percent). Seventy percent of the 100 students who could differentiate between active and passive euthanasia thought that active euthanasia should not be considered murder, but 69 percent were cognizant it was so considered in Puerto Rico. Eighty-three percent of first year students but only 61 percent of third year students thought that physicians should alleviate suffering of terminally ill patients. Medical schools should provide a serious, unprejudiced and complete discussion of euthanasia and other life and death issues in their curricula. A humane orientation of medical students should be given as much emphasis as other aspects of professional training.

Attitude to Death↗