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Biomedical subjects

O R Madsen

Publications and source records attributed to O R Madsen.

5 recordsLinked to original sources
PubMed1992

[Demonstration of bacteriuria in elderly hospitalized patients. Comparison between leukocyte and nitrite strips and culture].

The purpose of this study was to assess the accuracy of test strips for urinary nitrite and leucocytes for detection of bacteriuria in elderly patients. The material consisted of 213 urine samples from 85 women and 26 men (median age 79 years, range 60-93 years) within the first two days in hospital. The results of the test strip reactions were read in the department and in the laboratory. The strip test results and symptoms of UTI were compared with culture results. 27% of the samples showed significant bacteriuria on culture (> or = 10(5) colonies/ml urine). 21% of the 102 patients who had submitted two urine samples within the first two days had significant bacteriuria in both samples. Less than half of these patients had symptoms of UTI. The false negative rate of test strips (defined as the number of proven laboratory UTIs not demonstrated by the test strips, expressed as a percentage of the total number of proven UTIs) was 29% in the department and in the laboratory it was 13%. 15% of the test strips at the laboratory failed to detect significant E. coli infections which were predominant. In conclusion, we found that it is advisable to perform urine culture if symptoms of urinary tract infections are present.

Aged↗
PubMed1992

[Reflex dystrophy after reconstruction of the axillary artery].

Reflex sympathetic dystrophy (RSD) is a complex syndrome of pain, trophic changes and vasomotor instability affecting the limbs. Numerous theories have been suggested to explain the pathophysiology. None is universely accepted. In most of the patients reported, an antecedant event such as trauma or surgery is implicated in the initiation of symptoms. We describe a case of reflex sympathetic dystrophy developing after reconstruction of a. axillaris. To our knowledge there have only been a few previous descriptions of reflex dystrophy following vascular surgery. The mechanism of reflex sympathetic dystrophy secondary to vascular trauma is discussed. Presumely, damage to the arterial wall by trauma may initiate abnormal reflex activity and lead to RSD. We suggest that vascular surgery should be considered as a potential risk factor for the development of RSD.

Arterial Occlusive Diseases↗
PubMed1991

[Attitudes to cholesterol measurement and intervention among general practitioners in Bornholm].

In 1985 an explanatory report was published about investigation and treatment of hyperlipidaemia. This report, together with a consensus report published subsequently, formed the background for a nationwide cholesterol campaign. The attitudes of general practitioners to measurement of cholesterol and intervention must be considered to have decisive influence on performance of the goal of the consensus report, viz, reduction of the incidence of ischaemic heart disease (IHD). By means of a nine-page questionnaire, an attempt was made to assess the attitudes to measurement of cholesterol and intervention among the general practitioners on Bornholm. Out of the 35 questionnaires sent, 27 were returned (77%). Just under 40% of the general practitioners would screen all men aged between 20 and 59 years. Approximately 25% would screen women in the same age group. Opinions were unanimous about screening patients with diabetes, hypertension or IHD. Attitudes towards intervention were, by and large, in agreement with the cholesterol limits recommended in the explanatory report. In general, the general practitioners had well balanced attitudes towards tracing and treatment of individuals with raised serum cholesterol with relevant consideration of cholesterol as an important risk factor in the development of IHD.

Adult↗
PubMed1991

Mechanism of aminoglycoside resistance in Danish Staphylococcus aureus strains during the years 1979-1987.

A total of 49 gentamicin-resistant strains of Staphylococcus aureus isolated from blood (n = 26) or from other sites (n = 23) during the years 1979 to 1987 were evaluated for the presence of aminoglycoside-inactivating enzymes on the basis of minimum inhibitory concentrations measured by agar dilution as well as inhibition zone diameters determined by disc diffusion. Enzymatic activity was caused by AAC (6')III/APH (2") in 45 strains, and by AAC (6')III/APH (2") + APH (3') in four strains. No changes in the distribution of enzymatic activity were observed during the eight years.

Aminoglycosides↗