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Biomedical subjects

O Presslich

Publications and source records attributed to O Presslich.

54 records · Page 3Linked to original sources

[Maximal motor nerve conduction rate with lithium].

We examined the nerve conduction velocity (NCV) of 10 patients under long-term lithium therapy and 10 patients after a 3-month lithium therapy. In accordance with the literature concerning patients and normals under experimental treatment with lithium, we also found reduced NCV values. There were no significant changes in NCV during the first 3 months of lithium treatment. This could be due to the relative low lithium levels as well as to symptoms of manic-depressive Illness and the nerve examined.

Bipolar Disorder↗

[Statistical data analysis of physiologic parameters in patients with endomorphic-depressive phases. An attempt to explore the changeable effects between physiologic parameters, examination times during the phase and various experimental conditions].

Range-corrected (according to Lykken) physiological data from the parameters of heart rate (HF), respiratory rate (AF), skin potential (skin potential level; SPL; skin potential response, SPR) and skin resistance level, SRL; skin resistance response, SRR) were obtained under an acoustic activation paradigm in the course of a longitudinal investigation on 7 women with endomorph depression treated with thymoleptic medication. These data form the matrix for two- and threefold analyses of variance as well as for concordance analyses according to Kendall. During six measurements (three each taken in the morning and evening) one finds differing levels of activation: relatively low ones at the beginning and at the end, high ones during the 'labilization phase' of the treatment. The varying 'reactivity' to the diverse examination sequences of an acoustic activation program is little affected by the degree of these changes; patient-specific 'characteristics' of the course of the activation are just as recognizable throughout the course of the investigation as are 'stimulus-specific' reactions. Each of the parameters is appropriate for the estimation of different physiological variables; SPR seems rather to be a situation-specific variable, HF and AF are probably suitable for establishing the level of activation, while changes in SPL seem to represent patient-specific characteristics.

Adult↗

[Orally-administered taurine in therapy-resistant epilepsy (author's transl)].

The anticonvulsive action of taurine, was tested in 9 therapy in 9 therapy-resistant patients with a high incidence of seizures. Taurine was given orally (1.5-7.5 g daily) over a period of 4 to 16 weeks and, despite the high dosage, no appreciable side effects were observed. During this time seizures disappeared temporarily for about two weeks in 5 out of 9 cases. In one case the seizure frequency was transiently reduced by approximately 25%, whilst in the remaining 3 cases no effect of taurine on seizure frequency was observed. The reason for the rapid disappearance of the anticonvulsive action of taurine is not known.

Administration, Oral↗

[Changes of heart rate in relation to diurnal variations in endogenic depression in women].

Heart rate data as produced by the subjects under investigation both in resting conditions and taken as total means per trial initially showed a trend towards ergotropic, clearly tachycardiac behavior; with the onset of thymoleptic drug therapy, there followed a further increase in heart rate, frequencies remaining more or less stationary on this level during the 26-day period observed by us. We found differences between morning and evening data of session A with 50% of subjects, 25% showing higher frequencies in their morning data, the reverse applying to a further 25%. The remaining 50% did not show any differences worth mentioning. At the end of the investigation period, the relation changed in favor of an increase in heart rate in the evening with 50% of subjects, whereas only 12.5% showed increased heart rate in the morning; 37.5% did not show significant differences. We could not demonstrate these results to be related to diurnal variation, degree of depression or course of the disease.

Circadian Rhythm↗

[Relations between subjective-psychological, physiological and behavioral levels in endogenous depressions].

In a longitudinal study of depressed episodes, changes in patients' state were examined by variables on the subjective-psychological, physiological and behavioral levels, respectively. Starting from the hypothesis of a systematic connection of these variables changes in patients' condition were defined from merely one of the above-mentioned levels, i.e. the test-psychological criteria relating to the subjective-psychological level ('Polaritätsprofil'). Results based on the rank analysis of covariance are presented which show the complex multivariate correlations between the three levels.

Analysis of Variance↗

[Connexions between instrumental delivery and cerebral damage in the infant (author's transl)].

An interdepartmental investigation was carried out on the incidence of brain injury, especially so-called minimal brain injury, after instrumental delivery of infants by means of forceps or vacuum extractor. There is no statistically-significant difference in the incidence of brain injury in infants delivered by means of forceps as compared with the vacuum extractor; there is, however, a significant increase in incidence of brain injury in infants following instrument-aided delivery as opposed to spontaneous delivery. A thorough explanation of the methods is given and the results are discussed.

Attention Deficit Disorder with Hyperactivity↗

[Long-term EEG investigations at the withdrawal of young polytoxicomanic addicts].

Serial EEG examinations (an average of three recordings in 14 weeks) are reported from adolescent inpatients (19 in number) who had been weaned of multiple drug abuse of an average duration of 2 years. At first examination seven had a normal EEG, 11 had a moderately abnormal EEG, and one had a markedly abnormal one. At final examination 13 had a normal EEG, five had a moderately abnormal EEG and three had definitely abnormal EEG's. The majority of the patients showed a decrease (significant at the 5% level), others an increase in EEG abnormalities. The relationship between the EEG changes in the course of the series on the one hand and the previous drug abuses is discussed.

Adolescent↗

[Clinical-psychopathological and electroencephalographic studies on patients with delusions of the paranoic and the paraphrenic types].

Clinical-psychopathological and electroencephalographic investigations are reported, carried out on patients with delusions of the paranoic and of the paraphrenic types. Abnormal EEGs were found more frequently in patients with a paraphrenic syndrome, and there was also a relatively more frequent response to flickering lights than in the paranoic group. There was also a more frequent response to flicker in patients with auditory hallucinations. Psychopathologically more florid delusional syndromes appear to produce abnormalities in the EEG more readily than do psychopathologically less elaborate syndromes.

Adolescent↗

[Management of breech delivery in primiparas - on the incidence of cerebral lesions. (author's transl)].

The investigation comprises a group of infants of primiparae with breech presentation after caesarean section and a group of infants delivered by means of manual aid. The school age children were examined on the incidence of brain injury. The investigation consisted of four parts; anamnesis, neurological status, EEG, psychological examination. Between these two groups there is not statistically-significant difference in the incidence of brain injury. The result of the investigation advocates the maintenance of selective sectioindication in case of primiparae and points to a possibly existing brain injury of infants with breech presentation before delivery.

Adolescent↗