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Biomedical subjects

O Petre-Quadens

Publications and source records attributed to O Petre-Quadens.

17 recordsLinked to original sources
PubMed1979

Maturation of REM-patterns from childhood to maturity.

The operational value of measuring paradoxical sleep (PS) as a percentage of total sleeping time has been questioned. The purpose of this study was to determine the interactions between the variations in hormonal secretions and paradoxical sleep in women of different age-groups. Three parameters were utilized: REM-percent, REM-density and the eye movement frequencies. The distribution of the time-intervals between the oculomotor signals as indicated by the ratio of the higher to the lower eye movement frequencies gives a clue as to the significance of the spatio-temporal organization of the brain-signals during paradoxical sleep. This notion introduces an internal temporal and dynamic dimension in the concept of REM or Paradoxical Sleep. From our results it appears that the changes in the ratio between the different types of oculomotor discharges are a function not only of hormonal fluctuations but also of age. This point of view opens a new possibility of interpreting the results.

Adolescent↗
PubMed1975

5-Hydroxytryptophan and sleep in Down's syndrome.

Polygraphic total night sleep electroencephalographic (EEG), electro-oculographic (EOG) and electromyographic (EMG) recordings have been made in 6 mongoloid infants who received oral 5-HTP for periods extending from 12 to 36 months. The doses were adapted to the infants' age and tolerance level. The oculomotor activity of paradoxical sleep (PS) was selectively analysed. The eye-movement (EM) density was significantly decreased in non-treated mongoloids as compared with that of normal age-related infants. Out of the 5-HTP-treated patients, however, the results in only 2 were within the limits for normal age-related infants. 5-HTP failed to induce any long-term differences in the EM frequencies. In fact, the drug had a short-term effect lasting up to 8 days. An increase in muscle tone and an improvement of motor behaviour were the only long-lasting results.

5-Hydroxytryptophan↗
PubMedDate not supplied

Paradoxical sleep characteristics and cultural environment. Preliminary results.

The Temiars are a tribe of negroid pygmies of basically Proto-Malaysian affinities. Field-work in the Malaysian jungle provided some observations on the sleep-wakefulness cycle of two young Temiar adults. This cycle was monophasic circumstances permitting. Their rest-activity cycle at night was similar in the jungle and in the laboratory. Polygraphic total night-sleep recordings were made with both of them in the EEG laboratory in the Hospital Besar in Kuala Lumpur. The eye-movement frequencies of PS were compared with those from young adults of the West. Although the differences were not statistically significant, the Rem-densities of the Temiars were constantly at the low side. The significance of the results are being discussed.

Adult↗