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Biomedical subjects

O Pavkovceková

Publications and source records attributed to O Pavkovceková.

At least 19 recordsLinked to original sources

Zinc and copper metabolism in nephrotic syndrome.

The effect of proteinuria on urinary zinc and copper excretion was studied in children with nephrotic syndrome (NS). Clearance, fractional excretion, and urinary excretion of zinc and copper were significantly higher in children with relapse of NS than in the same children with remission of NS or in healthy children. A linear correlation was found between proteinuria and urinary zinc and copper excretion in relapse of NS. The results of this study suggest that zinc and copper deficiency in NS may be related also to increased urinary zinc and copper losses.

Adolescent

Increased incidence of congenital hypothyroidism in Gypsies in east Slovakia as compared with white population.

Ethnic Gypsies represent 9 percent of total population of East Slovakia. However, during first three and half years of compulsory screening of congenital hypothyroidism (CH) there were 15,346 Gypsy newborns which was 16.8 percent of a total number of 90,760 newborns. Out of these Gypsy newborns 7 cases of CH were found (i.e. 1:2192), while 12 cases of CH were observed among 75,414 white newborns (i.e. 1:6284), which was significantly less than that in newborns Gypsies (P less than 0.05). Since the far highest coefficient of inbreeding ever reported for any European population or ethnic groups has been found by others in newborns Gypsies living in Slovakia (Fg = 0.017 obtained by genealogic method and Fi = 0.084 obtained by the method of isonymy), it may be suggested that a high incidence of CH in newborns Gypsies may be due to some genetic and hereditary factors. Though a direct interrelationship cannot be definitely established from the present data and still remains far from to be elucidated, the present observation may be considered as a contribution to the study of this problem.

Congenital Hypothyroidism

[Renal excretion of zinc in children with kidney diseases].

The authors investigated the renal zinc excretion in 33 children with chronic glomerulonephritis, in 30 children with tubulo-interstitial nephritis, 12 children with nephrotic syndrome and 31 children with isolated haematuria. In all groups the Zn clearance was slightly raised, as compared with the control group. The Zn clearance was highly significantly elevated in nephrotic syndrome. The authors correlated the urinary finding (proteinuria, haematuria, leucocyturia) with Zn clearance. Children with a positive urinary finding had a higher Zn clearance than those with a negative finding. There was a close correlation between selective proteinuria and Zn clearance in children with nephrotic syndrome.

Child

[Lympho-renal fistula in lymphatic imaging].

On the case of 10 years old boy with chyluria the authors emphasize the importance of lymphographic examination for proving the pyelolymphatic connection. The lymphographic examination was applied after the complete examination including computer tomography and ultrasound, since these examinations did not prove changes of the urinary and lymphatic systems which could explain the milky clouding of the urine lasting for several months. Changes in the biochemical profile were significant as well as non-constant ejaculation of milky cloudy urine from the opening of the right ureter. The lymphographic examination proved the link between the lymphatic urinary systems with changes on the lymphatic vessels and nodes.

Child

[Chyluria].

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Child