Search PubMed⌕ Search

Biomedical subjects

O Papadopoulos

Publications and source records attributed to O Papadopoulos.

At least 55 records · Page 3Linked to original sources

An experimental study on the pathogenicity of the caprine herpesvirus type 1 (CHV-1).

The pathogenicity of caprine herpesvirus type-1 (CHV-1) in goat kids and lambs was studied. Two experiments were carried out. In the first, two Saanen goat kids and four lambs of a local breed were infected intravenously with the Swiss strain E/CH of the virus. Clinical reaction was severe in the kids, but it was very mild in the lambs. Virus was excreted from the kids in higher titres and longer than in lambs. Virus was also isolated from tissue specimens but only from a kid that died on post inoculation day 4 (PID 4). The gross- and histopathological lesions were more severe in kids. In the second experiment only lambs were used. They were dexamethasone treated and then virus inoculated. A very mild infection developed. The lambs did not shed the virus, neither the virus was isolated from their tissues collected at necropsy. Nevertheless histopathological lesions were seen. In both experiments the animals seroconverted on PID 10.

Animals↗

Divided nevus of the eyelid.

The two-stage surgical treatment of an adult female patient who presented with a congenital divided nevus of the left upper and lower lid is described.

Eyelid Neoplasms↗

[Plastic surgery of the eyelids after tumoral excision. Apropos of 299 cases].

Plastic surgery of the peri-orbital area after tumor resection is a special and interesting field of reconstructive surgery. Our experience concerns the surgical treatment of 299 malignant tumors of the skin of the peri-orbital area in 291 patients. Basal cell carcinomas were the most common but we also had 8 squamous cell and 4 mixed carcinomas and 1 malignant melanoma. Among these tumors, 277 were primary and 22 were recurrences: 5 after X-Ray therapy, 9 after surgery elsewhere, 4 after electrocautery and 4 after combined treatments. The lower eyelids and the inner canthus areas were the most frequently involved in our series with relative infrequency in the outer canthus and upper eyelids. We used direct closure and local flaps in the repair of most of our patients, but we also used some full thickness skin grafts by preference for the upper eyelid. Complications consisted of 8 cases of ectropion and 2 flap necroses for which a revision was performed in some cases. Concerning our carcinological results among the 123 patients with one year minimum follow up we noticed 4 recurrences which represents a percentage of 3.2%.

Aged↗

A preliminary investigation on the latency of the goat herpesvirus BHV-6.

An experiment was designed for a preliminary investigation of the caprine herpesvirus BHV-6 latency. The experiment was carried out in two steps. In the first, the virus inoculated six kids and the control, showed a mild infection and excreted the virus for 4-12 days. The second part started about one month after the cease of all symptoms and the virus isolations of the first part. No immunosuppression and therefore no virus reactivation could be achieved after eight daily administered injections of dexamethasone (0.15-0.50 mg/kg BW), as it was judged by the hematological, virological, pathological and serological findings.

Animals↗

The epizootiology of caprine herpesvirus (BHV-6) infections in goat populations in Greece.

Previous preliminary studies had shown that caprine herpesvirus (BHV-6) infections exist in many countries where goats play an economical role. The extensive serum survey made in Greece reveals that the virus must be widespread because more than 50% of the goats have antibodies. The bucks were found to have a higher evidence of infections than the female goats. The kids possessing maternal antibodies became seronegative at the age of 4 months and new antibodies appeared at the age of 7-8 months. Observations in 2 closed goat herds showed that the virus does not spread during the mating and lactating period. Neutralization titres increased or new infections in seronegative animals occurred after the summer when breeding took place. The virus is present in a latent state and recurrent infections are assumed to occur. In spite of that all our efforts to isolate the virus were unsuccessful, even after experimental immunosuppression.

Age Factors↗

[Microsurgical repair of the vas deferens. Apropos of 115 cases].

The demand for the reversal of vasectomy in the treatment of sterility has been increasing over the past decade. Microsurgery is acknowledged to be the best non-traumatic procedure for this reconstruction. This article reviews 115 patients treated by microvasovasostomy over a period of six years. Evaluation of the results shows 76% of patients with a positive seminal analysis, and 52% informed the authors that their partners were pregnant. In addition to the technical aspects (i.e. the non-traumatic manipulation of tissues using microsurgical procedures) the titer of antisperm bodies in the patient's serum and seminal plasma seems to play some part in the recovery of fertility.

Follow-Up Studies↗

Curative and aesthetic results of surgical treatment of 138 basal-cell carcinomas.

We herewith present a review of 138 basal-cell carcinomas, mostly on the face, that were treated by surgical excision and immediate repair. In a few cases, frozen sections were taken to ensure complete excision of the neoplasm. Local flaps were favored; distant flaps and full-thickness skin grafts were required in selected case. The recurrence rate with a minimum of 3 years of follow-up is 2.1%. Cosmetic results, evaluated by the patients themselves and by one of the authors (G.D.) who did not participate in the surgery, were judged "excellent," that is, without visible scars or deformities, in 61.4% of the cases, and "good" in 31.4%. The results are discussed.

Aged↗

[Surgical treatment of basal cell epitheliomas of the nose (author's transl)].

The surgical treatment of basal cell epitheliomas of the nose is based on wide excision and histological control with preferably an extemporaneous examination. The decision to operate should be made by a group consisting of the radiotherapist, the surgeon, and the dermatologist. Repair is usually carried out immediately, once it is certain that ablation is complete. There are no true contra-indications due to the age of the patient and treatment is less costly than irradiation. Surgery is essential for reconstruction of the nasal pyramid destroyed partially or completely by the tumor and consists of a reconstructive rhinoplasty using a frontal flap. Lesions that are of moderate dimensions but are too large to be treated by electrocoagulation, especially if they are close to the nasal orifices, are a good indication for surgery. A graft, especially a total skin graft taken from behind the ear or from the subclavicular region, is usually used. However, local flaps using the excess skin at the root of the nose (glabellar flap) or from the cheek (nasogenial flap) give excellent results. The authors describe the results obtained in a series of 93 patients in whom relapses were observed in only 7.6%. The only 3 cases in which the recurrence was not able to be treated, all three patients eventually dying, were cases in which the tumors had been operated upon for recurrences after radiotherapy.

Adult↗