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Biomedical subjects

O P Steeno

Publications and source records attributed to O P Steeno.

12 recordsLinked to original sources
PubMed1998

Gregorius-Josephus Jacquelart, born in 1759, the first andrologist at the University of Leuven.

At the time of his death in 1776, most medical doctors in Paris challenged the views of Théophile de Bordeu on the "hormonal" action of internal secretions. At the University of Leuven, however, his concepts on the hormonal activity of semen had been positively approached in 1780 on the occasion of a public debate (disputatio), conducted by the medical student, Gregorius-Josephus Jacquelart. Therefore, we consider G.J. Jacquelart as being the first andrologist at the University of Leuven.

France↗
PubMed1984

Side-effects of salazopyrin on male fertility.

The author critically studied the twelve papers and letters to the editor published since 1979 regarding toxic effects of Salazopyrin on male fertility. A direct toxic side-effect of Salazopyrin on the maturation of sperm cells is apparent, but associated influencing factors are the basic illness itself and associated therapy forms, such as steroids, that also influence spermatogenesis. The mechanism of action of Salazopyrin is still a matter of dispute. Possible (and possibly combined) interfering factors are: an anti-folate action with influence on the rapid turnover of dividing spermatogenic cells, an anti-prostaglandin effect on motility and toxic effects of the sulphapyridine substance of Salazopyrin.

Adult↗
PubMed1983

Comparison of scrotal scintigraphy and thermography for the diagnosis of varicocele.

Varicocele is the most frequent cause of male subfertility. Several invasive and noninvasive techniques can be used to visualize scrotal phlebectasies. In this study sequential scintigraphy after intravenous injection of 99mTc-albumin was compared with tele-thermography. The normal and pathological images are described. The more obvious the clinical condition, the more lesions were revealed by scintigraphy (29.6% in subfertile men suspected of having variococele; 76.9% in patients with first degree varicocele; and 100% in Grades II and III cases). In 55 cases (of a total of 76 cases explored by radioisotopic techniques), the comparison of the thermographic results with the scintigraphy results suggests that scrotal scintigraphy is less sensitive. However, there are more false positive thermographies expressed as a discordance with clinical examination, which indicates higher specificity of scintigraphy. In conclusion scrotal scintigraphy cannot be considered as the screening procedure of first choice for varicocele, but it can give complementary information, especially when thermographic results are at variance with the clinical examination.

Diagnostic Errors↗
PubMedDate not supplied

Occupational influences on male fertility and sexuality. I.

The authors present herewith a survey of occupational influences on male fertility and sexuality. From literature data of the last 15 years, the potential risks of physical factors (traumatisms, temperature, radiation, micro-waves), of chemical factors (metals, mineral oils, hormones, pesticides and herbicides, neurotoxins, vinylchloride and analogs, carbondisulfide), of physio(patho)logical factors (infectious diseases occupationally acquired, low back syndrome) and of psychological factors (stress, alcoholism) are discussed. The authors also discuss the methodological aspects in monitoring the fertility and sexuality of male workers. As conclusion, they warn physicians, practising occupational medicine, to be aware of these potential risks regarding gonadal function and to neglect no longer the reproductive and sexual functions of the male. In the future, these problems will be faced more than at present, because of the increasing production of very active and toxic substances. Occupational hygienic measures are the first step in preventing environmental pollution hazards.

Adult↗
PubMedDate not supplied

Oigarche: the age at first ejaculation.

In our study the mean age of the age at first ejaculation in Belgium is 13 yrs 2 mos, corresponding with a testicular volume of 10 ml with the orchidometer of Prader. These data are in agreement with those of Laron et al. (1980) and Richardson and Short (1978). The relationship between the age at first ejaculation and the testicular volume means that once this testicular volume (10 ml) has been reached, the question about the presence of ejaculations no longer need be posed "prematurely" (and becomes the possible cause of feelings of inferiority). The age at first ejaculation certainly can be used as an index of genital and sexual maturation in male puberty.

Adolescent↗
PubMedDate not supplied

Clinical and physical evaluation of the infertile male: testicular measurement or orchidometry.

SUMMARY: For the quantitative determination of the testicular size or volume, two groups of apparatus are available: on the one hand, model testes, which are extremely valuable in longitudinal and cross-sectional studies during the period of pubescence, and on the other hand, measuring devices, with which the testicular dimensions can be specified. The latter instruments are helpful chiefly during the adolescent years and the diagnosis of problems surrounding fertility. The testicular volume can be calculated subsequently from the specific testicular measurements. The formula, for computing the volume of an ellipsoid, seems to be the most suitable for this purpose. Appliances also have been developed, which allow the largest (longitudinal) dimension (in mm) and the testicular volume (in cm3) to be read off simultaneously. A tonometer can be useful to quantitatively estimate the testicular consistency, which is a parameter of the testicular integrity at the level of tubular function (spermatozoa production).

Anthropometry↗