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Biomedical subjects

O P Bol'shakov

Publications and source records attributed to O P Bol'shakov.

At least 19 recordsLinked to original sources

[Morphologic and morphometric characteristics of the femoral head in experimental necrosis and after incomplete occlusion of the femoral artery].

Partial occlusion (by 70-80%) of the femoral artery (FA) below its bifurcation with the deep femoral one was created in 15 dogs 6 months after modeling of aseptic necrosis of femoral head (FH). The dynamics of local circulation was evaluated using the methods of hydrogen clearance, angiography, flowmetry, polarography and mingography. FA and neighboring vessels as well as FH bone tissue were studied using histological, histochemical and morphometric methods. It was found that partial occlusion of FA below its bifurcation with the deep femoral branch resulted after 180-240 days in a redistribution of blood flow in favor of the latter along with a formation of collateral vessel widening as well as in the change in the circulation vector in the direction of the hip joint. This contributed to FH revascularization after modeling of its traumatic aseptic necrosis. The results of the morphological analysis indicate the activation of osteogenesis and gradual replacement of the necrotic area in FH with a newly formed osseous tissue and are suggestive of possible application of this method for clinical use.

Animals↗

[On technique of surgical treatment of extravasal stenosis of the celiac plexus].

Under analysis were the results of intraoperative observations during surgical treatment of 243 patients with extravasal stenosis of the celiac trunk. Special attention was given to anatomical correlation of the celiac trunk, celiac plexus, median arcuate ligament and median crura of the diaphragm involved in the compression of the celiac trunk. For the development and substantiation of optimal methods of decompression of the celiac trunk 106 anatomical preparations were investigated. The variants of the anterior diaphragm arteries and of the celiac trunk vessels were revealed whose injuries can result in intraoperative bleedings. Different variants of the operative technique depending on the anatomical conditions are proposed.

Adolescent↗

[Individual variability in the topography of the thoracic duct and its significance for the treatment of chylothorax by a video endosurgical method].

A possibility for clipping the ends of the damaged thoracic duct in chylothorax treatment by video endosurgical method was supported by the experiment performed in 10 dogs and topographoanatomical study carried out in 158 corpses of adults. The correlation found allows to forecast the possible position of thoracic region of the thoracic duct both by the thoracic cage shape and topography of the adjacent large anatomic elements.

Adult↗

[Anatomic characteristics of relatively inaccessible zones of thoracic duct and principles for improving surgical approaches].

The analysis of data obtained from investigation of 158 cadavers of adults with the use of complex of anatomic methods and from experiments on video-endosurgical installation revealed that the following ways should be combined to expose thoracic duct relatively inaccessible zones: a method of opened access to thoracic duct using high traumatism elements (clavicotomy and pericardium dissection), video-endosurgical method of access to thoracic duct regions located on the bottom of infundibular recess and use of mechanical clipping for faster block of thoracic duct lumen.

Adult↗

[The variability in the interrelations of the terminal portions of the thoracic duct and the left vertebral vein and its importance in applying a lymphovenous anastomosis].

Peculiarities of interrelations between the thoracic duct terminal regions and left vertebral vein were studied in 158 human cadavers. In case of long and thin neck trunks of the thoracic duct and vertebral vein ere established not to adjoin. Here a lympho-venous end-to-side anastomosis may be applied in vertebral vein mobilization. In short and thick neck intercrossing of the trunks was observed. In this case any type of lympho-venous anastomosis may be applied.

Anastomosis, Surgical↗

[Surgical methods of preventing aorto(prosthesis)intestinal erosions and fistulae in surgery of the abdominal aorta and its branches].

An analysis of 72 reconstructive operations on the abdominal aorta (in 5 cases shunts of the celiac trunk and superior mesenteric arteries were performed) fulfilled by the authors has shown that in order to prevent the development of the aorto(prosthetic)-intestinal erosions and fistulas and possible extension of the inflammatory process to the synthetic prostheses from the adjacent organs it is necessary to use the corresponding technical means and the following methods of protection of anastomoses and vascular transplants: protection of the prosthesis by local tissues or greater omentum flaps, selection of the corresponding diameter and length of the prosthesis.

Aorta, Abdominal↗