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Biomedical subjects

O Ortiz

Publications and source records attributed to O Ortiz.

At least 37 records · Page 2Linked to original sources
PubMed1995

Posttraumatic meningioma: explanation of an epidemiologic dichotomy.

A 23-year-old soldier sustained a penetrating gunshot wound to the right frontoparietal region of the head in 1971 while serving in Vietnam. In 1984, he developed headaches and seizures, and a meningioma was found at the cranioplasty site. Recurrent meningiomas, requiring resection, developed at this site in 1988 and 1990. In 1994, he developed right proptosis. An extensive mass involving the right intraorbital region and the anterior and middle cranial fossa was found. Pathological examination of this tumor demonstrated malignant meningioma. Although antecedent head trauma has been implicated as a risk factor for meningioma, epidemiological studies of this association have yielded divergent conclusions. An explanation for this epidemiologic dichotomy is suggested.

Adult↗
PubMed1993

Resolution of focal CT hypodense lesions in patients with subarachnoid hemorrhage.

Cerebral infarction in the setting of vasospasm due to subarachnoid hemorrhage (SAH) is a known complication of aneurysmal rupture. Computed tomography (CT) has been instrumental in making this diagnosis; however, focal hypodense lesions on CT scan do not always represent infarcted tissue. Two patients are presented here who had CT hypodense lesions in regions of cerebral vasospasm following subarachnoid hemorrhage.

Adult↗
PubMed1992

Differences in skeletal muscle and bone mineral mass between black and white females and their relevance to estimates of body composition.

This study tested the hypothesis that black females have an increase in skeletal muscle and bone mineral mass compared with white females matched for age (+/- 5 y), weight (+/- 2 kg), height (+/- 3 cm), and menstrual status. Conventional [underwater weighing, whole body 40K counting (WBC), 3H2O dilution] and newly developed (dual-photon absorptiometry) techniques were used to provide ethnicity-independent estimates of body composition in 28 pairs of matched subjects. Black females had greater appendicular skeletal muscle (P less than 0.001), bone mineral (P less than 0.001), and total body potassium (TBK) (P = 0.05) compared with white females. Two classic coefficients used in body composition research [density of fat-free mass (FFM) for underwater weighing and TBK/FFM for WBC] differed significantly (P less than 0.05) between black and white females; currently applied coefficients underestimated fat in black females. This study confirms that black and white females differ in body composition and that errors in fat estimates occur when ethnicity is not accounted for in body composition models.

Absorptiometry, Photon↗
PubMed1991

Case report 678. Sporotrichal arthritis.

A case of articular sporotrichosis occurring in the wrist and ankle of a 39-year-old man is reported. Review of the literature on this disorder confirms the diagnostic difficulties presented by this usually chronic, progressive, fungal arthritis. The diagnosis of this entity should be considered in the evaluation of any patient presenting with a progressive destructive arthritic process. The pathological and radiological features of a typical case are discussed and the mechanisms of infection and type of individual affected by this disease are described.

Adult↗
PubMed1989

Percutaneous nephrostomy in the management of renal candidiasis.

A case of Candida infection of the kidney was successfully managed by percutaneous means. This case demonstrates that percutaneous nephrostomy is a simple, effective technique not only for drainage, extraction of fungus balls, and irrigation with amphotericin B, but also for examining the renal collecting system and obtaining urine samples for diagnostic culture verification. Because of the toxicity of antifungal drugs, the incorporation of this percutaneous technique into standard management will benefit the patient with a life-threatening renal fungal infection.

Candidiasis↗
PubMed1987

Parenteral nutrition via the peritoneum with dextrose and amino acids.

We filled the peritoneal cavity of 9 rabbits through a silastic pediatric Tenckhoff-type catheter with a volume 10% of the animal's weight of an isotonic 'absorption mass' made up by a hydroelectrolytic solution to which 535 mg/dl glucose and 2.53 g/l L-amino acids were added. Then we slowly and continuously infused into it a mixture of a 50% glucose solution with a 13.3% L-amino acid solution to provide 10 +/- 0.2 g glucose and 2.18 +/- 0.24 g L-amino acid (0.334 +/- 0.039 g nitrogen) per kilogram weight in 24 h. So we mimicked the scheme and quantities of total parenteral nutrition. Osmolarity and volume of peritoneal fluid were constant throughout the experiment. In the first 4 h, glucose concentration rose to 1,407 +/- 431 mg/dl and amino acids decreased to nearly two thirds of their initial concentrations. Thereafter, both amino acid and glucose concentrations stabilized. Blood sugar rose slightly from basal 145 +/- 16 mg/dl to a maximum of 200 +/- 59 mg/dl. Plasma amino acids showed a moderate but irregular variation with increases in proline, glutamic acid, methionine, lysine and arginine concentrations, a decline of isoleucine and tryptophan concentrations and no changes for the other amino acids given. There were no variations in plasma values of sodium, potassium, chloride, urea, creatinine, osmolarity, total proteins and hematocrit. We achieved a glucose absorption of 8.72 +/- 0.94 g/kg weight (87.07 +/- 10.11% of the administered amount) and a nitrogen absorption of 303 +/- 47 mg/kg/day (91.4 +/- 14% of administered amount).(ABSTRACT TRUNCATED AT 250 WORDS)

Amino Acids↗
PubMed1977

Sinusoidal fetal heart rate pattern and severe fetal anemia.

This report describes a case of a sinusoidal fetal heart rate (FHR) pattern encountered in a fetus at 34 weeks' gestation during antepartum fetal stress testing because of maternal hypertension. Delivery of the fetus was accomplished, and the newborn was found to be severely anemic and hypotensive due to a massive fetomaternal transfusion. Some pathophysiologic mechanisms are suggested, and the clinical significance of this finding is discussed.

Adult↗
PubMed1975

The independence of membrane potential and potassium activation of the sodium pump in muscle.

The membrane potential (Em) of sartorius muscle fibers was made insensitive to [K+] by equilibration in a 95 mM K+, 120 mM Na+ Ringer solution. Under these conditions a potassium-activated, ouabain-sensitive sodium efflux was observed which had characteristics similar to those seen in muscles with Em sensitive to [K+]. In addition, in the presence of 10 mM K+, these muscles were able to produce a net sodium extrusion against an electrochemical gradient which was also inhibited by 10- minus 4 M oubain. This suggests that the membrane potential does not play a major role in the potassium activation of the sodium pump in muscles.

Animals↗