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Biomedical subjects

O Onunkwo

Publications and source records attributed to O Onunkwo.

9 recordsLinked to original sources

First report of an infectious bursal disease outbreak in a vaccinated chicken flock in Anambra State, Nigeria.

Infectious bursal disease was reported in a flock of 7-week old vaccinated chickens. Clinical findings and post-mortem changes were classical as well as the microscopic pathology of the bursa. Bursal homogenates from dead birds were positive for IBD virus antigen in agar gel diffusion test (AGDT). Convalescent sera obtained from birds 14 days following the onset of clinical signs were also positive for IBD virus antibody in AGDT. Seven-week old susceptible birds, each infected i/m with 0.1 ml of a bursal preparation from the outbreak, showed clinical signs of IBD on the 3rd day and were all dead by the 6th day. Their bursae were also positive for IBD virus antigen in AGDT. This is the first recorded outbreak of IBD in Southern Nigeria following inoculation with a locally produced vaccine.

Animals↗

Characterization of a Newcastle disease virus isolated from a parrot (Psittacus erythracus) in Nigeria.

The characteristics of a Newcastle disease virus isolated from a parrot (Psittacus erythracus) in Nigeria were examined using standard laboratory tests. Minimum lethal dose in embryos was 10(-10), mean death time 44.8 h. The intracerebral and intravenous pathologic indices were 1.65 and 2.42, respectively. The virus was resistant at pH 3 and pH 7.2 and the hemagglutinin was thermostable at 56 C for 120 min. Of 10 mammalian species of erythrocytes examined, those of equine and rat were not agglutinated. The isolate was typed as a velogenic viscerotropic Newcastle disease virus.

Animals↗