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Biomedical subjects

O Lavie

Publications and source records attributed to O Lavie.

41 records · Page 3Linked to original sources

Serous papillary adenocarcinoma of the endometrium. A unique entity with a grave prognosis. Case report and review of the literature.

A case of Papillary Serous Adenocarcinoma of the endometrium is described. This unique variant of endometrial carcinoma was described initially only 10 years ago. The tumor has distinct pathological characteristics and a very grave prognosis. The importance of identifying this unique tumor type is related to appropriate treatment as well as to correct statistical analysis of endometrial carcinoma.

Antineoplastic Combined Chemotherapy Protocols↗

Risk factors for lateral ankle sprain: a prospective study among military recruits.

In a prospective study of risk factors for lateral ankle sprain among 390 male Israeli infantry recruits, a 18% incidence of lateral ankle sprains was found in basic training. There was no statistically significant difference in the incidence of lateral ankle sprains between recruits who trained in modified basketball shoes or standard lightweight infantry boots. By multivariate stepwise logistic regression a statistically significant relationship was found between body weight x height (a magnitude which is proportional to the mass moment of inertia of the body around a horizontal axis through the ankle), a previous history of ankle sprain, and the incidence of lateral ankle sprains. Recruits who were taller and heavier and thus had larger mass moments of inertia (P = 0.004), and those with a prior history of ankle sprain (P = 0.01) had higher lateral ankle sprain morbidity in basic training.

Analysis of Variance↗

Renal cell carcinoma metastatic to the ovary. Ultrasound and CT appearance.

Three years following nephrectomy for renal cell carcinoma, a 54-year-old woman presented with symptoms secondary to ascites, and a large left adnexal mass. A large predominantly cystic, partially solid, septated mass with thick irregular margins was found on ultrasound and computed tomography scans. Pathological examination revealed renal cell carcinoma identical to the original tumor. The etiology and appearance of metastatic disease to the ovary are discussed.

Ascites↗

Computerized nuclear morphometry for the prediction of inguinal lymph nodes metastases in squamous cell carcinoma of the vulva.

This study evaluated the sensitivity and specificity of computerized morphometry in predicting lymph nodes metastases (LNM) in patients with squamous cell carcinoma (SCC) of the vulva. Histologic samples obtained from 20 consecutive cases of SCC of the vulva with positive inguinal LNM were morphometrically assessed and compared with samples from 20 consecutive cases of vulvar SCC negative for LNM. Computerized morphometry was performed on tumor cells and on adjacent nonneoplastic epithelial cells located 2-4 mm from the tumor margins. Computerized morphometric variables of tumor cell nuclei in patients with negative LNM significantly differed from those in patients with positive LNM. Morphometric differences in nuclear size and contour regularity were detected when comparing the nonneoplastic nuclei adjacent to the tumor of both groups. Multivariate analysis showed that the only independent predictors of LNM were the depth of the invasion (P= 0.005) and the mean nuclear roundness of the nonneoplastic nuclei adjacent to the tumors (P= 0.008). Using these variables, a discriminant score revealed a sensitivity of 90% and a specificity of 86.4% for predicting LNM in SCC of the vulva. Our data suggest that cells from the primary tumors with LNM differ morphometrically from primary tumors with no LNM. In addition, normal epithelial cells adjacent to the tumor express morphometric changes between the two groups. The results of our study justify the need for a prospective study of a larger number of patients to evaluate the reproducibility and the clinical use of the data.

Adult↗

The management of an early-missed abortion after radical trachelectomy--a case report and a review of the literature.

UNLABELLED: Radical trachelectomy (RT) has been reported for almost 20 years. This case report describes and addresses the issue of the clinical management of early-missed abortion in a patient after RT with a cerclage. CASE: A 35-year-old woman who had a RT 2 years ago due to cervical carcinoma stage IB1 presented with a missed abortion of an 8-week gestational age. At the end of the RT, a cerclage suture was inserted in the remaining internal oss of the cervix. The patient went through a cervical dilatation followed by suction curettage guided by ultrasonography without compromising the cerclage. This case report suggests that dilatation and suction curettage without compromising the cervical cerclage is a feasible option in the clinical management of early abortion in a patient after RT.

Abortion, Missed↗