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Biomedical subjects

O Laccourreye

Publications and source records attributed to O Laccourreye.

At least 163 records · Page 9Linked to original sources

[Deglutition and partial supracricoid laryngectomies].

The indications of partial supracricoid laryngectomy have become more numerous since the first descriptions made by Majer, Labayle and Piquet. The study of the published functional results emphasizes that false passages during deglutition are the main postoperative problem. This technical note is aimed at drawing attention to the various points to be respected intra- and postoperatively to allow swallowing in as physiological a manner as possible.

Cricoid Cartilage↗

Carcinoid (neuroendocrine) tumor of the arytenoid.

We reviewed three cases of neuroendocrine carcinoid tumors of the larynx, located on the arytenoid cartilage, treated between 1962 and 1985 at the Laennec Hospital, University of Paris (France) V. Staging was performed according to the 1979 American Joint Committee for Cancer Staging Classification. None of the lesions were associated with symptoms of the carcinoid syndrome. Local and nodal recurrences, distant metastasis, and survival were analyzed. Among the 112 reported carcinoid (neuroendocrine) tumors of the larynx, arytenoid location represented 28.6% (32/112) of the cases. A review of these 32 patients was performed to analyze the problems associated with that location.

Adult↗

Synchronous arytenoid and pancreatic neuroendocrine carcinoma.

Neuroendocrine laryngeal carcinoid tumours are uncommon. The supraglottis is the main location of these tumours. Eighty-one cases have been reported in the world literature. We present the first case of a synchronous laryngeal and pancreatic neuroendocrine tumour.

Arytenoid Cartilage↗

Vertical partial laryngectomy: a critical analysis of local recurrence.

The purpose of this study was to evaluate local recurrence following vertical partial laryngectomies in 416 patients with either T1N0M0 or T2N0M0 glottic carcinoma. Local failure was reported according to the T stage, the precise tumor location within each stage, the true vocal cord mobility, and the surgical procedure performed. No local recurrences were observed among 42 patients who underwent thyrotomy and cordectomy when the tumor was confined to the middle third of the mobile true vocal cord. Local failure occurred in 8 of 111 (7.2%) patients in whom hemilaryngectomy was performed for tumors confined to one mobile true vocal cord. There was a diverse group of lesions within each T stage that responded differently to the surgical approaches. The differences in the initial recurrence rates are discussed in terms of careful preoperative assessment and choice of surgical technique for early glottic carcinoma.

Adult↗

[Comparative study of temporal parameters of alaryngeal voices. Esophageal and tracheo-esophageal voices].

Recent studies have established significant acoustic and phonetic differences between tracheo-oesophageal (TE) and conventional esophageal voices (EV). 12 alaryngeal voices (2 esophageal, 6 myomucosal shunts, 4 tracheoesophageal phonatory protheses), and 7 normal laryngeal voices were recorded and analyzed. Speech timing including voicing and pauses distribution was evaluated and compared to laryngeal voices. Speakers with TE voices using pulmonary air were able to preserve the rythm and the syntactico-semantic structure of their speeches, as opposed to speakers with EV who often had to insufflate air into the esophagus and therefore had a staccato-like speech. The phonation time was quite similar in both situations, but the length and the number of pauses made the difference.

Aged↗

[Combined approach to malignant tumors of the ethmoid and other paranasal sinuses. Principles and results].

The authors present their experience concerning combined transfacial and neurosurgical procedures in the treatment of carcinomas of the ethmoid sinuses. 109 ethmoid-spheno-orbital tumors were treated at our department from 1982 to 1990: 85 were located into the ethmoidal and/or sphenoidal sinuses; 78 of these were malignant. Among the 65 ethmoidal carcinomas which were operated through a combined route, 48 underwent an induction chemotherapy and 19 a post-operative radiotherapy. The surgical technique is detailed, mostly the intra-cranial approach and the reconstruction of the cranial basis. Clinical results, and particularly the actuarial survival rates are discussed. The 5-year actuarial survival rate is 40% for all first hand ethmoidal adenocarcinomas. The figure reaches 52% for the patients without intra-cranial extension. At last, the 5-year actuarial survival rate is 100% for patients having a complete clinical response to induction chemotherapy.

Actuarial Analysis↗

[Adenoid cystic carcinoma of the parotid gland].

The authors report 7 cases of adenoid cystic carcinoma arising in the parotid gland between 1969 and 1990. All patients underwent surgery. Radiotherapy was performed twice following surgery. Local failure, nodal failure and distant metastasis are analyzed. Death appears to be related mainly to local failure. Radiotherapy does not seem to improve the local control obtained by surgery alone. Surgery must then be total and if necessary mutilating. Radiotherapy associated to surgery might be useful in case of extensive tumors for which complete eradication is not possible. A review of the world literature is performed.

Adult↗

[Cancer arising in a cyst of the thyroglossal tract].

Two new cases of thyroglossal cyst carcinoma are reported. Such cancers concern rather young women. The diagnosis must be suspected whenever a thyroglossal cyst is associated with cervical adenopathies. The most performing investigation seems to be fine-needle aspiration guided by echography. The malignant diagnosis is made during surgery by frozen section of the lesion, confirmed by histology. Two type of cancer must be distinguished: squamous cell carcinoma and carcinoma of thyroid type. The management of squamous cell carcinoma includes a large resection. For thyroid type carcinomas, total thyroidectomy and bilateral neck dissection are to be considered. Because of up-to-date insufficiency following, it is difficult to make a prognosis.

Adolescent↗

[Extension to the infratemporal fossa of malignant tumors of the face].

The authors report about the experience of the N&T department of Laënnec Hospital with tumors of the upper facial structures invading the infratemporal fossa. This invasion is currently diagnosed preoperatively owing to the progress made in imaging. The involvement of the posterior wall of the sinus is the first CT sign. 45 tumors extended into the ITF, including 35 maxillary tumors. For the latter, the frequency of invasion of the ITF was of 38% for all histological types, and of 26% for epidermoid carcinomas. Trismus, the most characteristic sign, was present in 45% only of the tumors studied. Facial pain also was frequent. The prognosis of these tumors is extremely poor, as the survival rate was of 17% at 3 years, with a mean survival of 10 months. The failures of treatment were essentially local. The surgical treatment proposed associates scooping out the ITF to maxillary resection.

Carcinoma, Squamous Cell↗

[Muco-epidermoid tumors of the parotid gland. Diagnostic and therapeutic attitudes].

On the basis of a retrospective series of thirteen cases treated between 1969 and 1989, the authors have studied the diagnostic and therapeutic issues connected with mucoepidermoid parotid tumors. The diagnosis is histopathological, but it is sometimes difficult to establish because of the histological polymorphism of these tumors. The degree of malignancy is variable and generally low. It is determined according to clinical and histopathological criteria, although there is not always a correlation between these criteria and the malignancy of evolution. Surgical exeresis is sufficient to cure most of these tumors. However, postoperative radiation therapy is indicated in case of tumoral invasion. Out of the ten cases of mucoepidermoid parotid tumor, nine were treated in first intention with exclusive surgery, and one case underwent postoperative radiation therapy. No local recurrence was noted. Out of the three patients who had a second-intention surgical exeresis, one died after repeated recurrence in spite of the complementary radiation therapy.

Adolescent↗

Supracricoid laryngectomy with cricohyoidoepiglottopexy: a partial laryngeal procedure for glottic carcinoma.

The partial horizontal supracricoid laryngectomy with cricohyoidoepiglottopexy consists of resection of the whole thyroid cartilage and paraglottic space. The cricoid cartilage, the hyoid bone, most of the epiglottis, and at least one arytenoid cartilage are conserved. Thirty-six patients with squamous cell carcinoma of the glottis who underwent this procedure from 1974 through 1986 are presented. All 36 recovered physiologic deglutition and phonation. None required a permanent tracheotomy. The 3-year actuarial survival rate was 86.5%. The local recurrence rate was 5.5%. The indications for the procedure are carcinomas of the glottis that 1) spread beyond the confines of the membranous portion of the true vocal cord or 2) present with limitation of true vocal cord mobility. The procedure is presented as a useful alternative to radiotherapy, partial vertical laryngectomy, and total laryngectomy in select cases of glottic carcinoma.

Adult↗

Treatment of Frey's syndrome with topical 2% diphemanil methylsulfate (Prantal): a double-blind evaluation of 15 patients.

Fifteen patients with severe gustatory sweating after total parotidectomy and facial nerve preservation were asked to take part in a double-blind study. All patients were alternatively treated with topically applied placebo and topically applied 2% diphemanil methylsulfate (an anticholinergic agent). A 10-day period was allowed between applications for return of symptoms. Two-percent diphemanil methylsulfate provided partial relief in 33.3% of patients and total relief in 40% of patients. Involvement of the hairy temporal line region with gustatory sweating was the main reason for failure. Duration of relief varied from 2 to 4 days. The only side effect was dryness of the mouth noted in two patients.

Administration, Topical↗

Supracricoid laryngectomy with cricohyoidopexy: a partial laryngeal procedure for selected supraglottic and transglottic carcinomas.

The partial horizontal supracricoid laryngectomy with cricohyoidopexy consists of resection of the whole thyroid cartilage and paraglottic space, as well as the epiglottis and the whole pre-epiglottic space. The cricoid cartilage, the hyoid bone, and at least one arytenoid cartilage are spared. Sixty-eight patients with squamous cell carcinoma of the supraglottis who underwent this procedure during the period from 1974 through 1986 are presented. Conventional horizontal supraglottic laryngectomy was contraindicated in all cases. All but three patients (95.4%) recovered physiologic deglutition, and none required a permanent tracheostomy. The 3-year actuarial survival rate was 71.4%. No local recurrences were encountered. The indications for the procedure are carcinomas of the supraglottis that 1. involve the glottis and anterior commissure, 2. invade the ventricle, 3. present with a marked limitation of true vocal cord mobility (transglottic lesions), and 4. invade the thyroid cartilage. The procedure is presented as a useful alternative to radiation therapy, horizontal supraglottic laryngectomy, and total laryngectomy in select cases of supraglottic carcinoma.

Adult↗

[Amalgamated and reinforced bone powder graft in the correction of the nasal ridge].

A number of surgical procedures have been described to correct irregularities of the consequences of excessive resection of the nasal ridge. Among these procedures the authors propose a bone powder graft mixed with tissue glue and reinforced with surgicel. The graft is in the form of a sheet of variable thickness which is malleable and can be perfectly shaped to fit the nasal ridge. It is positioned between the osteo-cartilagenous supporting structures and the skin. It smoothes out rough areas and compensates for any underlying loss of substance. It may be combined with a bone or cartilage graft which serves as a support and also acts to smoothe out the irregular form of the latter.

Bone Transplantation↗

[Local and lymph node recurrence of epitheliomas starting in the glottis, treated by partial laryngeal surgery: apropos of 432 patients].

Four hundred and thirty-two patients with a carcinoma of the true vocal cord, treated with a partial laryngectomy from 1972 through 1984, were retrospectively analyzed. All patients were staged as NO, MO. Survival and death rates were not presented. A three-year minimum follow-up was achieved in 97% of the cases. Local and cervical recurrences were presented and analyzed. Factors such as local tumor extent, impaired mobility of the true vocal cord, invasion of conus elasticus or thyroid cartilage, and positive margins of resection enhance the outcome of local and cervical recurrences. This present report underscores that thyrotomies, hemilaryngectomies, and cricohyoidoepiglottopexies should be adapted to the exact tumor location and the laryngeal mobilities. Cervical lymph node recurrence is less likely to happen if local control is achieved. The role and rationale for an associated elective ipsilateral cervical and paratracheal lymph chain dissection are presented and advocated.

Adult↗

[The versatile midface degloving approach. Re-updating the method, apropos of a case].

A recurrent adenoid cystic carcinoma of the hard palate extending to the maxillary sinus was resected through the versatile midface degloving approach. The surgical technique is discussed, and advantages and limits of the procedure are analyzed. The authors recommend this approach for midface tumors which avoids a facial scar and which sounds oncological.

Carcinoma, Adenoid Cystic↗