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Biomedical subjects

O Krauss

Publications and source records attributed to O Krauss.

At least 19 recordsLinked to original sources

In vitro model for the response to irradiation of different types of human intracranial tumours.

Twenty-seven human low and high grade gliomas and five meningiomas were cultured in vitro as tumour tissue and/or tumour cells. Cell survival or growth was taken as a measure of radiation response. Astrocytomas II-III and glioblastomas manifested individual patterns of radiosensitivity, ranging from 10 to 90 Gy. Meningiomas did not react. Our findings are consistent with the differences in radiosensitivity of human gliomas experienced clinically and corroborate the validity of the in vitro model.

Brain Neoplasms

[Measurement of the absorbed dose to the patient by computerized whole-body x-ray tomography with the aid of thermoluminescence dosimeters in an Alderson-phantom (author's transl)].

Radiation dosis for brain, lung, liver, and kidney examinations which were performed with computerized wholebody scanner (Ohio-Nuclear, 120 KV, 30 mA) was measured by LiF-TLD in the Alderson-Phantom. The absorbed skin dosis to the trunk by a single scan (filtration 6 mm A1) was found to be 1.2 rd at the entrance and 90 mrd at the exit. Patient investigations were simulated with a series of 5 scans. Under those conditions the maximum abdominal entrance dosis is 1.8 rd, at the body axis 700 mrd and near the exit 250 mrd. In this example the dosis to the gonads is less than 2 and 4 mrd, if the distance is more than 15 cm between the last scan and the gonads. Scattered radiation in the Delta-Scan room during an investigation is 1.5 mR/scan and 0.3 mR/scan for a distance of 1 m and 2 m from the irradiated volume.

Brain Diseases