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Biomedical subjects

O Jacobsen

Publications and source records attributed to O Jacobsen.

12 recordsLinked to original sources
PubMed1978

Bladder function in healthy elderly males.

Bladder function was studied in 20 healthy elderly male volunteers using cystometry, uroflowmetry and voiding cystourethrography. Two persons were excluded from the study as neurological examination had shown evidence of organic neurological disease, and one person did not complete the study. 53% of the remaining 17 persons had detrusor hyperreflexia. Urinary flow rates were reduced and maximal intravesical pressures elevated in the persons studied, although they claimed to have a normal voiding pattern. No correlation was found between the reduction of urinary flow rate respectively increase in maximal intravesical pressure and the presence of detrusor hyperreflexia. The high incidence of detrusor reflex disturbances thus suggests that incipient infravesical obstruction in old age and possible subclinical impairment of the central nervous control of the micturition reflex are major etiological factors in detrusor hyperreflexia.

Age Factors↗
PubMed1977

The diagnostic value of intravenous pyelography in infravesical obstruction in males.

Intravenous pyelographies from 104 consecutive patients admitted for infravesical obstruction were studied with special reference to pathology of the upper urinary tract and the bladder, the size of the prostate and the bladder emptying. The incidental findings in the upper urinary tract did not influence the treatment of the infravesical obstruction. Furthermore the radiographic assessment of prostatic size, bladder trabeculation, bladder emptying, bladder stones and prostatic cancer was very uncertain. Thus intravenous pyelography in our opinion should not be performed as a routine procedure in patients with benign prostatic hypertrophy, but only on clinical suspicion of upper urinary tract pathology.

Adult↗
PubMed1976

Dysfunction of the bladder neck: a urodynamic study.

Urodynamic investigations were performed in 9 males, suffering from dysfunction of the bladder neck (detrusor bladder neck dyssynergia). The parameters of micturition were compared with the values in normal males and in patients with prostatic obstruction. By introducing a new factor, the maximum opening time, we found a characteristic pattern in dysfunction of the bladder neck, making selection of patients for endoscopic incision of the bladder neck possible. The maximum and mean flow rates increased significantly in 5 patients treated with incision of the bladder neck. The diagnostic value of voiding cystourethrography and urodynamic investigation is discussed.

Adult↗
PubMed1975

Quantitative rating of depressive states.

A step-by-step analysis of Beck's and Hamilton's rating scales showed that both scales failed to differentiate adequately between moderate and severe depression measured by a global clinical assessment. Each item of the scales was tested for calibration, ascending monotonicity, and dispersion parallel to the clinical assessment. Twelve items of Beck's scale and six items of Hamilton's scale were found valid with respect to these criteria. Those items should be taken into account in future research for baseline ratings and for change ratings of depressive states quantitatively.

Adult↗
PubMed1975

Quantitative rating of manic states. Correlation between clinical assessment and Biegel's Objective Rating Scale.

We have investigated Biegel's manic-state rating scale and found the interrater reliability high when the scale was administered both by nurses and psychiatrists. In our study of validation, we tested each item of the scale for calibration, ascending monotonicity and dispersion parallel to a global clinical assessment of the manic state. Six of the scale items were then found valid and those items differed from the valid items in studies of Biegel by including increased social contact. Like Biegel, we found a positive correlation between items concerned with depressed mood, indicating a fluctuation in the mood of manic patients during 8 hours of observation.

Adult↗