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Biomedical subjects

O Heymans

Publications and source records attributed to O Heymans.

62 records · Page 4Linked to original sources
PubMed1995

Ear malformations in the mouse embryo following maternal administration of triazene, with clinical implications.

Triazene administration to 10-day pregnant mice gave rise to severe ear abnormalities, including middle ear ossicle malformations. The head of the malleus and the body of the incus were sometimes absent. In some instances, the stapes appeared dysplastic. The stapedial artery was often quite dilated, as well as other cephalic vessels, but qualitatively normal. Severe inner ear abnormalities were observed, as well as auditory nerve disruption, which was associated with central nervous system lesions. Multiple haematomas were present in the embryonic face, but ear abnormalities occurred even in the absence of local hemorrhages. We postulate a direct effect of the teratogen on the branchial mesenchyme. This model seems to be useful for the comprehension of human middle ear abnormalities, but does not constitute a phenocopy of hemicranial microscomia.

Abnormalities, Drug-Induced↗
PubMed1993

[Lipoma of the fingers].

Benign tumours of the hand are a common disease, usually corresponding to nodes. Other etiologies are less common. Lipomas of the hand are a rare feature, especially in the fingers. We present four cases of digital lipomas and a review of surgery of lipomas over the past ten years, and of the literature.

Adult↗
PubMed1992

[Fetomaternal alloimmunization: role of cordocentesis].

Twenty one pregnancies complicated by alloimmunization were managed by the use of intravascular method on an outpatient basis. One group was made of 9 women having had at least one pregnancy with a severely affected fetus. The other group was composed of 12 women without a previously affected infant; in 5 cases a situation at risk, either a transfusion (4 cases) or a severe obstetrical hemorrhage (1 case), was evidenced. Knowledge of fetal blood type (2 cases) and hematocrit determination obtained by fetal blood sampling allowed treatment individualized to the specific needs of each patient. In total 59 cordocenteses were performed, including 19 intrauterine transfusions.

Blood Transfusion, Intrauterine↗
PubMedDate not supplied

Thromboprophylaxis in microsurgery.

Microsurgical free tissue transfer has become a gold standard in a wide range of clinical situations. Thrombosis at the anastomotic site is not only the most common cause of failure of microsurgical operations, but it is also one of the factors resulting in microcirculatory intravascular thrombosis in free flaps. All conditions of thrombus formation, defined by Virchow in 1856, are encountered in free flap surgery. This literature review concerns the problem of thromboprophylaxis in microsurgery. All citations published this last ten years (1996-2005) concerning this problem are noted. Data are confronted with other specialties, particularly vascular surgery, or with large retrospective studies. Protocol used in our institution is presented at the end of this lecture.

Anastomosis, Surgical↗
PubMedDate not supplied

Metastatic involvement of ceco-appendicular segment: a diagnosis of right lower quadrant abdominal pain in patient receiving chemotherapy.

Metastases are a common feature during the evolution of breast cancer. However, gastrointestinal metastases, and especially ceco-appendicular ones, are very rare. Melanoma however frequently metastasize in the gastrointestinal tract. Ceco-appendicular metastases do not display any specific signs in cancerous patients. These rare metastases must be considered in the diagnosis of right lower quadrant pain in cancerous patients. The main differential diagnosis includes neutropenic enterocolitis, acute appendicitis, malignant intestinal obstruction and perforation of the bowel. The morbidity of gastrointestinal complications in patients with metastatic cancer receiving chemotherapy is significant and surgery is often the only chance of survival. The major clinical decision is whether or not to operate.

Abdominal Pain↗
PubMedDate not supplied

Lesser curvature Roux-en-Y gastric bypass as an alternative procedure to failed vertical banded gastroplasty: surgical technique and short-term results.

PURPOSE: The incidence of revisional surgery for failed vertical banded gastroplasty has increased markedly over the last years. Conversion to gastric bypass is considered as a good alternative with satisfactory long term weight loss without further revisional surgery. Nevertheless, significant morbidity and mortality is still associated with this procedure. New technical aspects make it safer and more effective. The aim of the work is to expose a surgical bypass technique to attempt to reduce morbidity. PATIENTS AND METHODS: Thirty patients have undergone conversions from failed vertical banded gastroplasty to a lesser curvature Roux-en-Y Gastric Bypass. Surgical technique is described in detail and early complications and initial weight loss were analyzed (mean follow-up: 12 months). RESULTS: The key points of the operation were the small vertical pouch, the complete transection of the distal bypassed stomach, the interposition of a jejunal limb between the two gastric shares and the latero-lateral gastrojejunal anastomosis without proximal ring interposition. For the entire series, we noticed one major complication, an acute pancreatitis causing anastomotic fistula and four mild complications, one bleeding on the excluded stomach, one bronchopneumonia, one pleural effusion and one wound dehiscence. The percentage of excess weight loss attained 56.1% at one year follow-up. CONCLUSIONS: There have been tremendous improvements in the safety of gastric bypass over the years. One year follow-up indicates that our surgical bypass procedure is secure with a low complication rate.

Adult↗