Hyperuricemia in type V glycogenosis.
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Glycogen Storage Disease↗
Biomedical subjects
O Hardiman
Publications and source records attributed to O Hardiman.
Interictal spiking and seizures.
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Electroencephalography↗
Evaluation of stroke management in an Irish university teaching hospital: the Royal College of Physicians stroke audit package.
BACKGROUND: There are few data regarding the standard of stroke care in Ireland. AIM: To investigate the level of documentation for 13 key areas of stroke management. METHODS: Using a validated stroke audit package, this study reviewed the medical records of 100 consecutive patients hospitalised with acute stroke. RESULTS: Documentation of stroke symptoms, risk factors, general examination and investigations (cranial computer tomography [CT] and carotid Dopplers) were satisfactory. Neurological documentation was variable, with power (87%), sensation (70%) and eye movements (63%) being the most frequently recorded features, while cognition (3%), visual fields (13%), gait (7%), incontinence (1%) and swallowing (0%) were infrequently recorded. Diagnostic formulation and an acute management plan were documented in less than half of patients, whereas cranial CT (93%) and carotid Dopplers (93%) were well documented. Secondary preventive measures were documented in two-thirds of patients at follow-up. CONCLUSIONS: These results serve as a baseline from which to initiate and monitor improvements in the service at our hospital, including the involvement of neurologists in stroke care, and will also allow assessment of the impact of such changes.
Aged↗
Interictal spike localisation with methohexitone: preoperative activation and surgical follow-up.
Thirty-four patients with intractable temporal lobe epilepsy underwent preoperative and perioperative EEG activation with methohexitone sodium. Subsequently, all patients underwent anterior temporal lobectomy with deep structure preservation. Preoperative spike localisation with methohexitone was concordant with peroperative recording in most cases. Large doses of methohexitone were administered to two patients, rendering the EEG almost isoelectric. Areas of abnormal spiking activity were refractory to the effects of methohexitone, and recovery was marked by an increase in spike frequency. Postoperative clinical evaluation confirmed the specificity of methohexitone for abnormally epileptogenic tissue.
Electroencephalography↗
Intracranial giant cell arteritis with fatal middle cerebral artery territory infarct.
A 37 year-old man who developed a fatal middle cerebral territory infarct was found at autopsy, to have widespread granulomatous angiitis involving meningeal and intracranial--extracerebral vessels but not intracerebral vessels or other extra-cranial vessels. The findings are unique and overlap with those of granulomatous angiitis of the nervous system (GANS) and classic giant cell arteritis (GCA). A possible precipitant for this devastating illness was a recent Chlamydia infection. The salient clinical and pathologic differences between GANS and GCA of the nervous system are discussed.
Adult↗
Access to health services in Ireland for people with Multiple Sclerosis and Motor Neurone Disease.
We conducted a telephone questionnaire to determine the utilisation of hospital and community based services by patients with Motor Neurone Disease and Multiple Sclerosis in Ireland. 94 MND and 188 MS patients participated in the study. MND patients were more likely to have free medical care than MS patients, despite legislation favouring the converse. Severely disabled MND patients were more successful at accessing free community-based services than were severely disabled MS patients. Private medical insurance conferred no advantage when obtaining services or purchasing equipment. Many patients were unaware of the specific roles of the various clinical professionals. There are significant deficiencies in patients' ability to access multidisciplinary services. Voluntary organisations often bridge the gap in service provision. An investment in services for people with chronic neurological disability is urgently required.
Community Health Services↗