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Biomedical subjects

O Gemer

Publications and source records attributed to O Gemer.

40 records · Page 3Linked to original sources
PubMed1993

Acanthosis nigricans and hyperandrogenism in a pregnancy complicated by diabetes.

BACKGROUND: Acanthosis nigricans and hyperandrogenism have been associated with diabetes mellitus accompanied by insulin resistance. However, these manifestations have rarely been reported to occur as a result of the insulin resistance of pregnancy. CASE: A 31-year-old woman with diabetes mellitus exhibited severe insulin resistance during pregnancy. At 32 weeks, daily administration of 500 U insulin was required to maintain glycemic control. Skin lesions typical of acanthosis nigricans appeared, and free testosterone levels were elevated (10.3 pg/mL). These manifestations resolved after delivery. CONCLUSION: This case may demonstrate a correlation between reversible gestational insulin resistance and acanthosis nigricans.

Acanthosis Nigricans↗
PubMed1992

Detection of scar dehiscence at delivery in women with prior cesarean section.

Transcervical examination of a prior cesarean scar after vaginal delivery is commonly advised. A retrospective study of 1023 parturients with prior cesarean delivery was undertaken, 475 of whom delivered vaginally. Thirteen cases of scar dehiscence were found at laparotomy, and only one case was discovered by transcervical examination. The value of routine postdelivery examination of uterine scar is doubtful.

Adult↗
PubMed1983

Absorption of orally administered gentamicin in infants with diarrhea.

The use of oral gentamicin in infantile diarrhea is recommended by some authors. However, no data are available concerning the gastrointestinal absorption of gentamicin in infants when the mucosa of the small intestine is damaged. In this study, plasma gentamicin concentrations were measured in 14 infants suffering from prolonged diarrhea and treated with oral gentamicin (mean dose: 17 mg/kg every 8 hr). Plasma gentamicin levels were determined serially following the oral dose. Although marked individual and erratic temporal variations existed, average plasma gentamicin concentrations were low and stable (0.31 +/- 0.12 micrograms/ml). A positive correlation was found between the duration of the diarrhea and plasma gentamicin concentrations (r = 0.59, P less than 0.05). It is theorized that the damage to the mucosa as it occurs in prolonged diarrhea allows the absorption of the polar gentamicin molecule.

Diarrhea, Infantile↗