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Biomedical subjects

O Gafencu

Publications and source records attributed to O Gafencu.

28 records · Page 2Linked to original sources
PubMed1998

[A giant arterial aneurysm with an inferior paramacular location--a clinical case].

The authors report the case of a 72-year-old patient with a sudden loss of the visual acuity of her unifunctional right eye. The ophthalmoscopy and the angiofluorography of the right eye showed a vascular tumour that is situated paramacular inferior, a long temporal arterial branch. Clinical and biochemical investigations permitted the diagnostic of arterial aneurysm developed on systemic hypertension and vascular fragility of the patient. It is very possible that an occlusive or a spastic downstream component to be at the origin of the aneurysm.

Aged↗
PubMed1998

[HLA antigens and ocular pathology].

The HLA antigen system is a complex of genes which have the control of a lot of cellular receptors with high role in histocompatibility, genes which code the born of all molecules may play a significant role in graft reaction and in starting the immunologic answer. The immunological study was demonstrated that many ophthalmological diseases are very deep linked by the HLA antigens.

Cornea↗
PubMed1997

[Carbonic anhydrase inhibitors with topical action in the treatment of glaucomatous diseases. A preliminary note].

Seven patients with open angle glaucoma were treated using Dorsolamida twice daily together Betablocant treat. Five patients with secondary glaucoma were treated with Dorsolamida three time daily as well three patients with edematous postimplant keratopathy. Intraocular pressure decreased with an average of 3-4 mm Hg and at the patients with corneal edema that decreased.

Administration, Topical↗
PubMed1997

[Conservative treatment in intraocular tumor in the remaining eye].

We present here, the case of a monophtalm patient, with the diagnostic of an intraocular tumour, situation when we have chosen a combination of conservative therapeutically means. Enucleation, as a radical method of treatment, is out of the question. We discuss, by turns, the main alternatives of conservative treatment: sclerochoroido-retinectomy, temporary fixation on the supraiacent sclera of radioactive discs, photocoagulation and cryocoagulation as single methods of treatment, justifying the present option: laser treatment associated with cryocoagulation and immunotherapy. We review some basic concepts of immunology, insisting upon the systemic and topical administration of IL-2. Up to the present, IL-2 is administrated topically only in pulmonary cancer and in cerebral tumours, after the operation, on the excision zones and in cutaneous malignant melanoma, with very good results. In ophthalmology, this is the first therapeutically attempt, using IL-2 in a case of intraocular tumour. The postoperative status and the results on short term put an end to this paper.

Aged↗
PubMedDate not supplied

[The use of prostaglandin compounds in treating glaucoma].

The theoretical part of this paper presents the mechanism of the IOP lowering effect using these drugs, the indications of treatment and the main side effects. The second part consist of the experimental study made on rabbits, using the izopropilic ester of (+)Cloprostenol as an hypotensive agent. We have registered the IOP values and the main side effect--conjunctival hyperemia. The third part consist of the clinical study, made on a test lot of 23 patients. We have used the same substance and in the experimental study, as a unique treatment or in association with a beta-blocker or a pilocarpine derivative. The following-up has implied: the IOP, the ophthalmoscopic appearance of the optic disc, the visual field, the visual acuity and the main side effects. In the end, we have formulated the conclusions of these studies.

Adrenergic beta-Antagonists↗
PubMedDate not supplied

[The treatment possibilities in macular degeneration in the elderly].

Age-related macular degeneration represents one of the most frequent disease of the old ones. The functional deficit is manifested in varied grades up tot the practical blindness as it is in the case of the exudative form. It does not exist any complete treatment now to produce the healing of these diseases but it is trying to find some efficient methods to improve the visual function. The best results were obtained by laser photocoagulation only in the places where it was indicated in the right time, and the surgery technics for removing the retinal membranes pre- or subfovea are made to complete the therapeutics palette of the age-related macular degeneration. The medical treatment and the optic one for the visual rehabilitation are sometimes the only methods of treatment for these categories of patients.

Aged↗
PubMedDate not supplied

[Biometry in cataract surgery with an implant].

In cataract surgery, the replacement of the opaque lens with an artificial lens is the ideal correction. For the present, the intraocular lens power determination is an essential part of the preoperative evaluation of an eye. The paper presents a short history about the development of implant power calculation, the main formulas used in present, the precise choice of postoperative refraction, the factors affecting accuracy of implant power calculation and some preoperative considerations (patients considerations, intraocular lens characteristics considerations). The final part contains some conclusions about the methods of implant power calculation.

Biometry↗
PubMedDate not supplied

[Marginal ectasia of the cornea resolved surgically].

The paper presents the case of a patient with Terrien's marginal degeneration. The moment of the exam, the corneal degeneration was in an advanced stage, being associated with secondary ectasia. The gutter developed as a results of the stromal progressive thinning was already circumferential. The only efficient treatment in this situation is an annular lamellar keratoplasty. We present the mais operatory moments, and also the main intra- and postoperatory incidents and complications. In spite of the fact that this operative procedure was already mentioned in literature, there are no certain proves; so, we are able to consider the achievement of the annular lamellar keratoplasty unique for this moment.

Adult↗
PubMedDate not supplied

[Ultrasonic biomicroscopy in the diagnosis of glaucoma].

For the beginning, the authors present a definition of the ultrasound biomicroscopy, together with the main fields of use, instrumentation and examination techniques. The second part of the paper analyses the contribution of the ultrasound biomicroscopy to the diagnosis of the open angle glaucoma and of the angle closure glaucoma. The final part contains some considerations referring to the main ocular diseases in which this technique is already used frequently and the perspectives for the future development of ultrasound biomicroscopy.

Glaucoma, Angle-Closure↗