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Biomedical subjects

O Fujita

Publications and source records attributed to O Fujita.

30 records · Page 2Linked to original sources

[Transition of occurrence of anisakiasis and its paratenic host fishes in Japan, with pathogenesis of anisakiasis].

The number of anisakiasis according to a nation-wide statistical survey totaled 4682 cases until June 1987 in Japan. Of these 4296 cases are gastric anisakiasis (including 215 cases of gastric terranovasis), 375 intestinal anisakiasis and 11 extra-gastrointestinal anisakiasis. Pseudoterranova larva does not invade the intestine, and worms are vomited in most cases. Clinical diagnosis of intestinal anisakiasis is more difficult than that of gastric anisakiasis, and it also is hard to find the worm itself in histopathological examination. Therefore the number of actual intestinal anisakiasis is probably 3 times more than that of the reported cases. The cases of gastrointestinal-wall perforation by worms are increasing, which means immune response by granuloma formation is important. The catches of paratenic hosts and the rate of infection vary with year. In addition, the kind of paratenic host fishes are different between the southern and northern areas of Japan. The paratenic hosts reported by patient are closely related to the catches of kinds of those fishes in the respective areas. Recently, cases by eating sardine are increasing in the southern area. Urticaria as a complication is related to the diagnostic rate, and intraperitoneal bacterial infection by the gastrointestinal perforation by worms is closely related to the prognosis.

Animals↗

Industrialization and mental health in Japan--mental health of large enterprise employees in their 40s and 50s.

Some difficulties in dealing with the mental health of large company employees in their 40s and 50s are discussed based on the authors' experiences as infirmary psychiatrists over the last decade. Some characteristics of Japanese enterprise are introduced and explained, such as "Tanshin-Funin," "Madogiwazoku" and "Shukko," which are intimately related to the management system of modern Japanese companies. The most prevalent psychiatric disorders among company employees are briefly discussed. They are usually diligent and hard-working middle management employees at least until the disorder becomes manifest. Form the socio-psychiatric viewpoint, it is assumed to be of increasing importance to deal with such a large cohort of individuals working in large companies as one of the significant objects of contemporary hygienic activities.

Adult↗

Septal lesions and biting attacks in rats bidirectionally selected for emotionality.

Twenty-nine colonies composed of one female and two male rats of high or low emotional strain were established. A dominant male of each colony was identified based on its attacks on an intruder rat. It was found that dominant males of the low emotional strain colonies were significantly more aggressive than those of the high emotional strain. Septal lesions or sham operations were given to dominant males of both strain colonies. Intruder tests were followed and several aggressive behaviors were measured by VTR observation. Biting attacks of the high emotional strain decreased for 10 days after septal latencies were shortened by septal lesions. Lesions X Strain interaction was significant. These results suggest that septal lesion effects on biting attacks are influenced by artificial genetic operations.

Aggression↗

[Study of suckling behavior in the rat: the effects of food deprivation of pups and lactational age of mother].

The effects of food deprivation (0-1, 2-3, and 22-23 h) of pups and of lactational age of mother (1-7 days, 16-22 days and own mother) upon suckling behavior of pups were investigated with the mother anesthetized. The effect of food deprivation was not evident prior to 11 days of age but deprived pups showed higher level of suckling than non-deprived pups at 16 and 21 days of age (Experiment 1). The effect of lactational age of mother was not found at 6-17 days of age but pups at 1-2 and 21-22 days of age showed lower level of suckling to the anesthetized mother which differed in lactational age from their own mother (Experiment 2).

Animal Population Groups↗

[Behavior-genetic analysis of responses in runway test as measures of emotional reactivity in rats: I.- phenotypic variations and heritability estimates based on offspring-parents regressions (author's transl)].

Individual differences of emotional reactivity were estimated from 6 kinds of responses measured in the Runway Test (modified ("Timidity Test") in 974 random-bred albino rats. 3 different estimates of heritability of these responses were calculated from the regressions of offspring on dam, sire, and midparent. The types and degree of the phenotypic variations are very different among the responses measured. Heritability estimates of 2 kinds of responses which are related to the behavior going to the remotest part of runway from starting box were relatively higher (.30-.55). Heritability estimates of starting latency, time in the starting box, and the number of sections rats traversed were medium (.20-.40). The estimates from defecation scores had lowest (.10-.30).

Animals↗