Search PubMed⌕ Search

Biomedical subjects

O Fenice

Publications and source records attributed to O Fenice.

22 records · Page 2Linked to original sources

[Large cutaneous penile flap in the tubular reconstruction of the urethra in complex recurrent and extensive bulbar-membranous strictures].

The surgical treatment of choice for bulbar-membranous urethral strictures should remove the stricture and achieve an end-to-end anastomosis between two spatulated surfaces to achieve better patency (Turner-Warwick technique [13]). When this is not possible because of recurrence, complex or longer strictures the problem is to choose between various candidate tissue types susceptible of forming a dependable neourethra. With this in view, we have used over the last twenty years a wide range of urethroplastic operating techniques using of scrotal skin [4], bladder mucosa free grafts [3], and dermo-epidermal free mesh grafts [10]. We achieved a significant improvement of the postoperative results with a procedure originally proposed by Quartey [9]. A well vascularised flap is dissected from the whole dorsal penile skin, drawn as far as the perineum and pulled laterally to the cavernous bodies to form the neourethra. We can thus depend on suitable and viable tissue of up to 13 cm in length. A large scalped area of skin is corrected by covering the surface of the penis with a free epidermal mesh graft. Between February 1989 and December 1991, 28 patients with relapsed bulbar-membranous complex urethral strictures underwent urethroplasty with a penile-skin flap. Normal urethro-cystographic imaging and urinary flowmetry figures showed at a three-month follow-up. All patients reported satisfactory micturition and no fistula occurred. Erectile deficiency was not reported.

Adult↗

[Anatomo-functional changes in the prostate and seminal vesicles with aging].

The anatomo-functional modifications of the prostate and the seminal pathways during the genital apparatus aging, (prostatic hyperplasia and hypotrophy of the seminal pathways and testis), are caused by hormonal modifications (inconstant increase of the gonadotropins LH-FSH, decrease of the peripheric utilization of testosterone, alterations of the adrenal secretion), by anatomical involutions (degenerations of the glandular, stromal and vascular components).

Aged↗

Bladder outflow after radical prostatectomy.

Postoperative bladder outflow was assessed in 150 patients subjected to radical retropubic prostatectomy for clinically localized prostate cancer. The overall mean (+/- S.E.M.) postoperative peak flow rates and residual urine volumes were 16.9 +/- 1.3 ml/s and 11.4 +/- 2.1 ml. According to flow nomograms, 22% of the patients were still obstructed postoperatively due to stricture of either the anastomosis or the urethra (12%), or to partial bladder denervation (10%). Scoring of subjective symptoms was not reliable in detecting postoperative outflow obstruction, while uroflowmetry with flow nomograms identified all obstructed cases. Radical retropubic prostatectomy can induce both mechanical and functional alterations of the distal urinary tract and a strict assessment of postoperative bladder outflow is recommended.

Adenocarcinoma↗

[Andrologic problems in prostatic carcinoma].

In our opinion, the attempt to save the sexuality and the erectile ability in a patient with a prostate cancer, in the respect of an absolute oncological radicality, should be recommended since potency represents for the patient a primary aspect in the quality of residual life. At the Institute of Urology of the University of Milan a study to identify pathogenetic mechanisms leading to erectile failure in the various phases of a prostate cancer was performed. From January 1988 to December 1993, 36 patients (range 50-60 years old) suffering from prostate cancer B1 stage (14 pts), B2 (20 pts) and C (2 pts) underwent to radical prostatectomy. Out of 24 pts reporting erectile ability before surgery, 10 was in B1 stage and underwent monolateral nerve-sparing technique. Out of these, 6 pts (60%) maintained the erection after the operation. The treatment with LHRH analogues weighted on loss of libido and erectile and erectile potent due to central androgenic delete. At our Institute 87 pts in treatment with LHRH analogues reported loss of erection in 80% of cases. In this group 22 underwent to an andrological examination. The exams (Dynamic penile Doppler, Dynamic Cavernosometry and stimulating test with intracavernous vasoactive drugs) confirm the absence of peripherical damages in the pathogenesis of the erectile dysfunction. Patient underwent radiotherapy develop a secondary impotence due to an obliterant progressive angioitis in a percentage ranging from 30 to 80%.(ABSTRACT TRUNCATED AT 250 WORDS)

Erectile Dysfunction↗