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Biomedical subjects

O Farru

Publications and source records attributed to O Farru.

15 recordsLinked to original sources

Bacterial pericarditis in infancy and childhood.

The authors report on a cooperative study of 43 cases of bacterial pericarditis observed in children. This disorder was suspected in patients with septicemia who developed symptoms and signs of pericarditis (precordial pain, muffled heart sounds, pericardial friction rub, cardiomegaly). Early diagnosis of this condition is now facilitated by echocardiography. A combination of medical and surgical treatments (appropriate antibiotic therapy after culture and sensitivity tests and early pericardial drainage) led to complete recovery in almost all of the cases (42 of 43). After long-term follow-up, no cases of constrictive pericarditis were observed.

Adolescent↗

[Transient myocardial ischemia in newborn infants].

Thirty new born babies with Apgar scores of 5 or less were randomly selected for clinical and electrocardiographic study. Twenty five had electrocardiographic changes of myocardial ischaemia (ST and T wave abnormalities). Generalised low voltage was a common finding (21 cases) whilst pathological Q waves were observed more rarely (5 cases) but did not seem to carry a poor prognosis. Seventeen babies had cardiac clinical signs: isolated tricuspid regurgitation or associated with cardiac failure. Five babies died; autopsy showed subendocardial infarction in all cases. The electrocardiogram of the survivors returned to normal within 15 days in 80% of cases. The authors discuss the physiopathology and demonstrate a clear relationship between neonatal hypoxia and myocardial ischaemia. Attentive clinical examination and systematic electrocardiography in these babies at risk seem to be justified for the detection and treatment of myocardial ischaemia.

Coronary Disease↗

[Vascular rings].

22 cases of several types of vascular rings are presented. Most of them were double aortic arch (15): 12 were operated on without mortality before the first years of age because of the great severity of the symptoms. The precocity of the symptomatology and the predominance of the respiratory distress is emphasized. Our data point out to the importance of the differential diagnosis of vascular rings in newborns and infants in the presence of laryngeal stridor or respiratory distress, essentially because the surgical correction is very effective and the risk of the intervention is minimal.

Angiocardiography↗