Search PubMedSearch

Biomedical subjects

O F Gabriele

Publications and source records attributed to O F Gabriele.

At least 19 recordsLinked to original sources

"High spinal" dysrhaphism. Case report of a complex cervical meningocele.

"High spinal" (cervical and upper thoracic) dysrhaphism usually involves either a meningocele or a dermal sinus tract. These high spinal lesions can have a complex intradural anatomy at the level of the lesion (as this case reports) and are associated with an increased incidence of lower spinal occult dysrhaphic anomalies. It is therefore recommended that patients with "high spinal" dysrhaphism undergo radiological evaluation of the entire spine to identify those patients with intradural anomalies, define the anatomy for surgery, and investigate the lower spine for associated occult anomalies.

Cervical Vertebrae

Middle ear prosthesis: significance in magnetic resonance imaging.

The Armstrong model of the Schuknecht gel foam and wire prosthesis was tested in the magnetic field of a 1.5 Tesla magnet. The wire component of the prosthesis was found to be non-magnetic. Patients with this prosthesis can therefore undergo MRI examination safely. Two previous articles from the non radiologic literature concerning the magnetic properties of metallic middle ear prostheses are reviewed.

Aged

The prone position for CT of the lumbar spine.

In scanning the L5-S1 disk space, the known technical difficulty is limitation of the gantry angle. A prone scanning technique used to examine the lumbar spine may help to overcome or lessen this problem. A prospective CT scanning of the L5-S1 level was performed in both the prone and supine positions on 25 patients who had low back pain and who had not undergone previous laminectomy or fusion. The angle between the S1 vertebral end plate and maximum tilted gantry line (15 degrees on the G.E. 8800) was measured in the supine position and compared with the same angle in the prone position. In 20 of 25 cases (80%), significant improvement in alignment was noted in the prone position. The prone scanning technique is also more desirable if CT is performed with metrizamide. Finally, printed images from the prone technique allow easier image-patient orientation for viewing in the operating room.

Back Pain

Ultrasonography and alpha-fetoprotein determination for antenatal detection of neural tube defects.

We review our experience in the antenatal detection of neural tube defects in a collaborative study between the prenatal diagnostic program of the Section of Medical Genetics and the Ultrasound Laboratory at the West Virginia University. In West Virginia the incidence of neural tube defects is two to three times the national average. The patients were referred to the sonic laboratory for a variety of reasons, even though they had not been classified in the high risk category. Our data confirm the advantage of ultrasonography for screening of the population in the early stages of pregnancy. The study also confirmed the value of serum and amniotic fluid alpha-fetoprotein (AFP) determination in conjunction with ultrasonography, especially when there is a positive family history. The combination of modalities appears to be the best means at present for detection of these severe disorders. Screening the general population in the early stages of pregnancy by means of ultrasonography, a noninvasive technic, can help to review fetal maturity and placental localization, as well as to detect neural tube defects. High risk mothers can then be followed up by further evaluations using serum or amniotic fluid AFP studies.

Amniotic Fluid

Traumatic para-mediastinal air cysts.

Two cases of traumatic para-mediastinal air cyst are presented. The air and fluid collection develops between two layers of the pulmonary ligament following trauma to the lung and rupture of alveoli adjacent to the pulmonary ligament.

Adolescent

Vessel tortuosity as a cause of posterior fossa cranial nerve syndromes.

Neurologic syndromes may be caused by mechanical vascular compression of cranial nerves in the posterior fossa. The clinical expression is variable and can be divided into two main groups. Isolated cranial nerve involvement is most frequently associated with tortuous, elongated vertebral and basilar arteries as well as redundant loops of the anteroinferior cerebellar artery. Pseudotumoral manifestations of cranial nerve involvement at the level of the cerebellopontine angle are more frequently related to aneurysms of the vertebral and basilar arteries.

Adult

Empty sella syndrome secondary to intrasellar cyst in adolescence.

A 15-year-old boy had growth failure and failure of sexual development. The probable onset was at age 10. Endocrine studies showed hypopituitarism with deficiency of growth hormone and follicle-stimulating hormone, an abnormal response to metyrapone, and deficiency of thyroid function. Luteinizing hormone level was in the low-normal range. Posterior pituitary function was normal. Roentgenogram showed a large sella with some destruction of the posterior clinoids. Transsphenoidal exploration was carried out. The sella was empty except for a whitish membrane; no pituitary tissue was seen. The sella was packed with muscle. Recovery was uneventful, and the patient was given replacement therapy. On histologic examination,the cyst wall showed low pseudostratified cuboidal epithelium and occasional squamous metaplasia. Hemosiderin-filled phagocytes and acinar structures were also seen. The diagnosis was probable rupture of an intrasellar epithelial cyst, leading to empty sella syndrome.

Adolescent