Biomedical subjects

O Erel

Publications and source records attributed to O Erel.

4 recordsLinked to original sources

PubMed1995

A sensitive staining method for NORs.

A sensitive staining method for nucleolar organizer regions (NORs) is described, using blue toning of AgNORs. NORs are loops of DNA which are transcribed into ribosomal RNA. NORs can be demonstrated by staining with silver nitrate, since NOR-associated proteins are argyrophilic, producing structures termed AgNORs. Normal blood lymphocytes were stained with both methods. The number and resolution of NORs increased 2-3 times by blue toning (30 mmol/l FeCl3, 11 mmol/l potassium hexacyanoferrate(III), and 33 mmol/l oxalic acid) compared with silver staining. A significant difference in the number of NORs was noticed between silver-stained and blue-toned cells (P < 0.001). The blue toning technique thus appears to be more sensitive in detecting NORs than the AgNOR method and may prove a useful alternative for applications in histopathology.

Chlorides↗

PubMed1995

Interrelatedness of marital relations and parent-child relations: a meta-analytic review.

It is widely assumed that a linkage, crucial to the understanding of child behavior, exists between marital and parent-child relationship quality. A meta-analysis of 68 studies was conducted to determine whether this linkage exists and, if so, whether the linkage is positive (as suggested by the spill-over hypothesis) or negative (as suggested by the compensatory hypothesis). Results supported the spillover hypothesis; a positive and nonhomogeneous effect size of moderate magnitude was found (d = 0.46). This suggests that research in this area can move beyond the question of whether a positive or negative association exists to identifying moderators of the association. Examination of the impact of 13 potential moderators did not support the existence of any of these variables that could be adequately examined. This suggests that the link between marital and parent-child relations functions as a more stable force than previously thought.

Adult↗

PubMed1994

Reliability and diagnostic efficacy of parents' reports regarding children's exposure to marital aggression.

Mothers, fathers, and 8- to 11-year-old children from 181 two-parent families independently reported on the occurrence of husband-to-wife physical aggression and wife-to-husband physical aggression; parents additionally indicated whether the child had been witness to the aggression. First this study examined interspousal agreement regarding whether parents have been physically aggressive toward one another and whether the child has witnessed interparental physical aggression. There was moderate agreement between parents as to the occurrence of physical aggression and only fair agreement as to whether the child saw or heard the aggression. Second, this study explored the diagnosticity of a joint parent report as an indicator of child exposure to marital aggression. Receiver operating characteristic (ROC) curves are presented separately for husbands' and wives' aggression, indicating the explicit trade-off between true positives (sensitivity) and false positives (one minus specificity) in using the joint parent report as a diagnostic indicator. Standard ROC analysis suggests that the joint parent report is equally diagnostic in predicting children's reports of exposure to husbands' and wives' aggression. Finally, decisions regarding how to use parent reports as an indicator of children's exposure to marital aggression are discussed as depending on the base rate of child reports of exposure and the objective sought in classifying children and/or families.

Adult↗

PubMedDate not supplied

Ventricular enlargement and premorbid deficits in school-occupational attainment in a high risk sample.

Using a subsample of subjects from the Copenhagen schizophrenia high-risk project, this study examined the relationship between ventricular enlargement and prospectively assessed deficits in premorbid school/occupational adjustment. Subjects with enlarged ventricles evidenced poorer premorbid school-occupational adjustment across three times of measurement spanning a period of 10 years. This effect was independent of the age and sex of the subjects and remained significant after controlling for psychiatric diagnosis. The results provide prospective evidence for an association between ventricular enlargement and poor premorbid history.

Achievement↗