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Biomedical subjects

O Dobrescu

Publications and source records attributed to O Dobrescu.

8 recordsLinked to original sources
PubMed1992

[Acute laryngitis in children].

Acute laryngitis is the most common form of upper airway obstruction in young children. Laryngeal obstruction requiring hospitalization and sometimes intubation may be due to viral infection or occasionally to allergic reaction. The natural course of the disease is impossible to predict; therefore, repeated clinical assessments are needed. Continuous worsening of dyspnea may suggest a diagnosis of bacterial tracheitis. High doses of corticosteroids combined with aerosolized racemic epinephrine can relieve the respiratory difficulties.

Acute Disease↗
PubMed1988

[Prevalence of Aeromonas spp. pediatric gastroenteritis].

A selective medium and biochemical tests were used to search for Aeromonas spp. in the stools of 536 children, more than 90% of whom had "gastroenteritis", seen at Sainte-Justine Hospital, Montreal, in June or July 1986. The organism was found in seven children, six of whom had bloody diarrhea. One of the six, a 6 1/2-year-old boy, required intravenous alimentation and later manifested ulcerative colitis; the other five recovered. The remaining child, a 14-year-old boy, had synovitis of the knee and spondylarthritis. Two of the seven carried other enteric pathogens. The authors discuss the pathogenicity of Aeromonas spp., which is not very marked in temperate climates, in human summer diarrhea and its possible role in the development of ulcerative colitis.

Adolescent↗
PubMed1986

Photoperiod, diet, and method of feeding on reproduction.

Effects of two lighting programs and three methods of feeding on semen production of Large White turkey males were investigated. Lighting programs of 14L:10D and 8L:16D were used during the reproduction period. The feeding programs consisted of: 1) a low protein ration (10% FF) containing 3,250 kcal ME/kg fed ad libitum, 2) a high protein ration (15% FF) fed ad libitum, and 3) a restricted intake high protein ration (15% R). The latter two diets contained 3,000 kcal ME/kg. Body weight, semen volume, and semen quality (sperm and seminal plasma protein concentrations) were measured weekly throughout the reproductive cycle from 26 to 52 weeks. There was no significant difference in the rate of weight gain of turkeys kept on 8L:16D and 15% FF from 16 to 52 weeks compared to those on 14L:10D and 15% FF. Decreasing protein from 15 to 10% and increasing energy levels of the diet decreased consumption significantly (P less than .05) from 16 to 52 weeks of age regardless of the light treatment. Mortality was lowest in the 10% FF and highest in the 15% R. Lighting treatment of 14L:10D significantly (P less than .05) increased semen volume and sperm concentration vs. the 8L:16D regimen. All the groups of males given 8L:16D had an endemic yellow semen syndrome (YSS) characterized by a combination of an elevated seminal plasma protein concentration (an average of 12.85 g/100 ml), abnormal spermatozoa, and numerous macrophages. Previous work is confirmed (Cecil, 1981) that low dietary protein can be used as a means of controlling body weight without any adverse effect on semen production or semen quality of Large White turkey breeder males.

Animals↗
PubMed1982

Benign familial neonatal convulsions.

Benign familial neonatal convulsions are a rare genetic seizure disorder inherited as an autosomal dominant trait. They consist of brief episodes of seizures, recurring during the first few days or weeks of life in otherwise normal babies; their prognosis is good. We report a family in which at least 12 members in three generations presented with this condition; they all had an excellent outcome.

Electroencephalography↗
PubMed1980

[Trichopoliodystrophy or Menkes disease].

Trichopoliodystrophy (also known as Menkes' kinky or steely hair disease), a recessive sex-linked syndrome, is characterized by severely retarded mental and physical development, convulsions, a particular phenotype and abnormalities of the hair, bones and arteries. Very low levels of copper and ceruloplasmin in the serum confirm the diagnosis. This rare disorder is caused by an inborn error of copper metabolism whose nature is not yet clear. Recent hypotheses favour either an abnormality in the transport of copper across the cell membrane or increased affinity for copper of the intracellular binding protein. Because the metabolic abnormality is expressed autonomously and irregularly in various tissues, the distribution of copper within the body is disordered. Up to now none of the many forms of copper therapy has succeeded in modifying the fatal course of the disease in humans. This article presents a new case, the first in Canada, and a review of the other 69 cases described in the literature. The new case illustrates, in addition to the classic picture, less well known features, such as diverticula of the bladder mucosa and serosa, as well as cortical atrophy and malformed cerebral vessels demonstrated by computer-assisted tomography.

Angiography↗