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Biomedical subjects

O D Schein

Publications and source records attributed to O D Schein.

95 records · Page 6Linked to original sources

Microbiology of contact lens-related keratitis.

We reviewed 397 cases of microbial keratitis examined at the Massachusetts Eye and Ear Infirmary, Boston, MA, U.S.A., from January 1982 through December 1985. Of these, 136 cases (34%) were related to contact lens use. Extended-wear contact lenses were used by 107 (79%) of these patients. Cosmetic contact lenses accounted for 59 (44%) of lens-related cases, aphakic contact lenses 44 (32%), and therapeutic (bandage) contact lenses 33 (24%). Fifty-three microbial keratitis cases associated with contact lens wear were culture-positive: 28 (52%) were gram-positive, and 19 (36%) were gram-negative. Mixed cultures, fungi, and Acanthamoeba accounted for two cases (4%) each. Pseudomonas aeruginosa was specifically associated with cosmetic soft contact lens use.

Adult↗

Microbial keratitis associated with contaminated ocular medications.

We studied seven cases of severe gram-negative microbial keratitis associated with the use of contaminated topical ocular medications. Five cases involved Pseudomonas aeruginosa, one involved Serratia marcescens, and one involved Proteus mirabilis. In each case the same organism was cultured from corneal scrapings and from the medication. Either prednisolone acetate (one case) or timolol maleate (seven cases) was implicated in all instances.

Administration, Topical↗

The spectrum and burden of ocular injury.

The authors conducted a hospital-based study to ascertain basic, descriptive epidemiologic information about ocular trauma in an urban setting. Over a 6-month period, 3184 patients presenting to our emergency ward with ocular trauma were studied. Severe injuries totaled 5.1% (ruptured globe, intraocular foreign body, hyphema, orbital/facial fracture) and 94.9% were superficial injuries and contusions. A disproportionate burden of severe ocular injury was borne by those less than 15 years of age. The work place accounted for 48% of all injuries and 50% of ruptured globes. Automobile repair-related tasks were specifically associated with injury. Sports injuries, although accounting for 3.4% of all injuries, were responsible for 60% of hyphemas and 10% of ruptured globes. Annual direct and indirect costs for these ocular injuries are estimated conservatively at $5 million and a loss of 60 work years. A large burden of preventable eye trauma is borne by both patients and society.

Adolescent↗

Bone marrow hemosiderin does not always reflect body iron stores.

Absence of hemosiderin from the bone marrow is sometimes encountered in patients who are not iron deficient. Two cases of autoimmune hemolytic anemia are described in which there was little or no hemosiderin in the marrow but large amounts in the spleen, which had been the major site of accelerated RBC destruction.

Aged↗

Preference values for visual states in patients planning to undergo cataract surgery.

To assess how preference values that cataract surgery patients assign to their preoperative visual states relate to visual acuity and problems in specific aspects of daily life, the authors interviewed 47 patients scheduled to have cataract surgery. Using a rating-scale technique with a scale from 0 (death) to 1 (excellent health), the patients had a mean preference value of 0.68 for their preoperative vision. Patients' preference values for their preoperative vision were more closely related to problems in specific aspects of daily life (especially feelings of depression and problems interacting with people) than to visual acuity in the operative eye, better eye, or worse eye, or a weighted average of visual acuities in both eyes. These results provide a rationale for relying more on patients' views about the effects of visual impairment than on measures of visual acuity when assessing the need for cataract surgery.

Activities of Daily Living↗