Search PubMed⌕ Search

Biomedical subjects

O Bical

Publications and source records attributed to O Bical.

At least 73 records · Page 4Linked to original sources

[4-year clinical experience with gelatin-resorcinol-formol glue in acute dissections of the ascending aorta].

The gelatine-resorcine-formol glue (GRF) was used to reinforce the tissues of 25 patients operated for acute dissection of the ascending aorta, between January 1977 and September 1980. The results were compared with those of a control group of 25 patients operated between 1970 and 1976 by "classical techniques". There were no significant differences between the two groups as regards age, anatomical and preoperative clinical states. The ascending aorta was replaced in all patients; the aortic valve was replaced three times (12 p. 100) in the GRF group and twelve times (48 p. 100) in the control group: the coronary arteries were bypassed or reimplanted in 20 p. 100 of patients in both groups. The average peroperative blood loss was 5,800 ml in the control group and 2,100 ml in the GRF group (p less than 0,01). There were four peroperative deaths (16 p. 100) in the control group and no peroperative deaths in the GRF group. Postoperative complications (renal failure, cerebral ischemia, persistent peripheral ischemia or infection) were much more common in the control group. They were responsible for eight hospital deaths in the control group and two hospital deaths in the GRF group (p less than 0,01). Therefore, global hospital mortality was reduced from 48 p. 100 (control group) to 8 p. 100 (GRF group) (p less than 0,01). Two late deaths occurred in the control group, but there were none in the GRF one, all survivors being in good clinical condition. Sixteen patients in the GRF group underwent 19 angiographic controls, 2 to 36 months after surgery. These investigations showed two moderate aortic regurgitations (8 p. 100), three persistent dissections of the descending aorta but a stable, good quality repair in the other patients. In conclusion, the use of GRF glue significantly reduced: 1) the number of aortic valve replacements, 2) per- and postoperative blood loss, 3) the incidence and severity of postoperative complications. The long-term survival rate (4 years) has improved from 40 to 91 p. 100.

Acute Disease↗

[Surgery of recurrent aortic dissection. Apropos of 6 cases].

The authors report a series of 6 cases of recurrent dissection, 4 of which were treated surgically, out of a total of 64 acute dissections of the aorta referred to the CMC Foch, between January 1969 and October 1981. Three types of recurrent dissection were identified: --"de novo" recurrent dissection: a new dissection occurring in part of the aorta previously unaffected with a new intimal tear; --recurrent dissection due to extension of the previous dissection; --"in situ" recurrent dissection. Surgery is the treatment of choice because of the poor prognosis. Extensive resection (sometimes carried out in several stages) and deep hypothermia are valuable techniques when part of the aorta giving off arteries to vital organs has to be replaced. The use of GRF biological glue in the treatment of the original acute dissection has been a significant advance in the prophylaxis of recurrent dissection as it ensures better repair of the distal false lumen (27% persistent false lumens). With respect to an extensive replacement of the dissected vessel, the authors advise operation in several stages, especially in young subjects with Marfan's syndrome who are at high risk of recurrent dissection. All cases of acute dissection of the aorta, operated or not, should be followed up indefinitely with clinical and radiological examination, completed, when necessary, by an angioscan and an aortography.

Adult↗

[Coarctation and dystrophic aneurysm of the thoracic aorta (author's transl)].

Coarctation and dystrophic aneurysm of the thoracic aorta are seldom associated. In this series of 6 patients the aneurysm, often voluminous, was located on the ascending aorta in 1 case, on the distal part of the aortic arch in 3 cases and on the descending aorta in 2 cases. Surgical treatment consisted of resection and prosthetic replacement of the coarcted and aneurysmal segment under extracorporeal circulation. In a 13-years old patient, however, the coarctation was repaired but the aneurysm of the descending aorta below it was deliberately left in situ. All six patients are now asymptomatic. Post-operative angiography was performed in 4 cases with satisfactory results. In all cases the dystrophic aneurysm resulted from lesions of the elastic fibers of the tunica media and was therefore different from other aneurysms associated with coarctations.

Adolescent↗

[Atrioventricular valve replacement in congenital cardiopathies. A series of 25 surgically-treated patients under 10 years of age].

A series of 25 congenital malformations of the atrioventricular valves underwent valve replacement (10 mechanical and 15 bioprostheses). Seven children died during surgery. The operative mortality was higher before 2 years of age (4/7) than in older children (3/18). It was also higher when valve replacement was performed at second intention (5/14) than when decided on from the outset (2/11). With an average follow-up over 3 years, 9 of the 18 survivors are considered to be good surgical results. Of the other 9, 3 are considered to be moderate results (2 associated subaortic stenoses), 3 present indications of reoperation for calcification of the bioprosthesis, and 3 died in the late follow-up period. This series suggests that plastic surgery of congenital malformations of the atrioventricular valves should continue to be developed.

Child↗

[Rupture of post-infarction left ventricular aneurysm. Apropos of 2 cases treated surgically successfully].

Two cases of post-infarction anterior left ventricular aneurysm complicated by localised rupture into the pericardium are reported. The clinical features of these cases were severe cardiac failure, 10 days or more after initial necrosis posing the problem of myocardial failure due to extension of the infarct. The surgical indications were brought by left ventricular angiography performed under intra-aortic balloon pumping: in the first case the diagnosis had already been suggested by the detection of a hemopericardium on echocardiography. In both cases, the surgical procedure comprised aneurysmectomy with reinforcement of the ventricular wall with bands of Teflon. The postoperative period was complicated due to the very precarious hemodynamics at the time of surgery. The functional status of both patients is now very satisfactory.

Echocardiography↗

[Iatrogenic arteriovenous fistulas in infants].

Iatrogenic arteriovenous fistulas in infants are usually due to an arterial puncture performed in the neonatal period. On the occasion of 5 cases who were operated on, the peculiar features of these fistulas are established. Surgery consists of endo-aneurysmorrhaphy.

Arteries↗

[Surgical treatment of thoracic and thoraco-abdominal aneurysms involving the Adamkiewicz's artery. Usefulness of deep hypothermia (author's transl)].

The authors present a new surgical technique for the treatment of thoracic and thoraco-abdominal aneurysms involving the artery of the lumbar enlargement (Adamkiewicz's artery) at its point of origin. In two patients the aortic segment giving birth to the artery was accurately located by angiography and re-impaired under deep hypothermia and extracorporeal circulation.

Adult↗

[Cold-induced paralysis of the phrenic nerve in open-heart surgery (author's transl)].

Cold-induced injury of the phrenic nerve after pericardial cooling during open-heart surgery has already been reported, but the post-operative consequences and long-term course of this complication have seldom been documented. Fifty cases (6.6%) of phrenic nerve paralysis were observed in a series of 750 patients undergoing open-heart surgery with topical cooling of the pericardium for myocardial protection. As infectious and respiratory complications (including atelectasis, bronchial obstruction, pleural effusion, pneumonia and bacteriaemia) were significantly more frequent (p less than 0.05) in these patients, assisted ventilation and intensive care were significantly more prolonged (p less than 0.01). Long-term follow-up of 42 patients (mean: 14 months; range: 3-42 months) showed inconstant and often incomplete regression of the paralysis. The complication can easily be prevented by using a plastic insulation pad during pericardial cooling and cold cardioplegia.

Cardiac Surgical Procedures↗

[Importance of echocardiography in the evaluation of surgical results in the tetralogy of Fallot].

M mode echocardiography was performed one year after surgical correction of Fallot's tetralogy in 32 patients (average age: 2, 7 years). All patients were asymptomatic without treatment and the average cardiothoracic ratio was 0,56 +/- 0,03. Echocardiographic indices of left ventricular function distinguished 4 patients with myocardial dysfunction (2 cases of poor myocardial protection and 2 double Blalock-Taussig anastomoses). Right ventricular diastolic internal dimensions were increased in 75 % cases. The ratio of right to left ventricular internal dimension was used to classify patients into three groups: Group I (ratio Less Than 0,70) 17 patients; Group II (ratio 0,70 Greater Than 0,80) 4 patients, and Group III (ratio Greater Than 0,80) 11 patients. This ratio was not related to the age of the patient of surgery or to the type of patch used on the right ventricular outflow tract but was related to the pressures recorded at operation after correction. A ratio Greater Than 0,80 was strongly suggestive of a significant residual abnormality which was often curable. Echocardiography has become an essential investigation in the follow up of Fallot's tetralogy after surgical correction: a right: left ventricular ratio Less Than 0,70 obviates the need of control catheterisation. On the other hand, a ratio Greater Than 0,80 is a strong indication for cardiac catheterisation even in the absence of clinical abnormalities.

Child↗

[Surgery of the descending thoracic aorta. Partial derivation between the pulmonary and femoral arteries: 29 cases (author's transl)].

The authors report on 29 surgical operations on the descending thoracic aorta, where partial extra-corporal circulation was established between the pulmonary and femoral arteries, using a straight Rigg's cannula inserted into the pulmonary artery. The blood flow rate in the shunt was of the order of 1,5 l/min. Owing to the ease with which the cannula is inserted and removed and to the possibility of switching to total extra-corporeal circulation the authors prefer this technique to all other types of partial derivation.

Aorta, Thoracic↗

[Replacement of the ascending aorta and aortic valve with re-implantation of the coronary arteries. Long-term results in 20 cases (author's transl)].

Total replacement of the ascending aorta and aortic valve using Bentall's technique was carried out in 20 patients with dystrophic (13 cases), chronic dissecting (4 cases) or acute dissecting (3 cases) aneurysm. Five patients died in the first month following surgery, but all patients operated upon for dystrophic aneurysm survived. The mean follow-up period for the 15 survivors was 39 months, and there was no late death. Thirteen patients are leading a normal life. Nine out of 14 control aortographies were performed 48 months on average after the operation. They showed normal and stable anatomical restoration of the aorta and coronary system. Total replacement of the ascending aorta seems to be the operation of choice for dystrophic aneurysm.

Adult↗