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Biomedical subjects

O Bercea

Publications and source records attributed to O Bercea.

53 records · Page 3Linked to original sources

[Clinico-radiological and functional correlations in endothoracic sarcoidosis].

A total of 35 cases of endo-thoracic sarcoidosis have been studied, of which 18 were confirmed histopathologically on bioptic samples. The analysis of the cases revealed the predominance of young subjects. The reactivity of PPD on cutaneous testing was negative in 60 percent of the cases, in accordance with the antimycobacterial fluorescent antibodies test. The insidious onset and evolution are noted, and the fact that the diagnosis was made on the occasion of routine investigations. Correlation of clinical signs with the radiologic aspects did not reveal significant data, but correlation with functional tests has revealed in 8 out of 11 cases presenting with dyspnoea an alteration of the respiratory function (an obstructive, a restrictive or a mixed syndrome). The importance of the diagnosis is stressed, in view of the application of treatment, that should not be delayed.

Adolescent↗

[The etiological profile of the pulmonary manifestations in AIDS patients (studies of 65 cases recorded in Romania up to 1 March 1993)].

HIV infection and its final form as AIDS were ignored by the public opinion in Romania till 1990. Nowadays it is real fact in our country. Out of total number of 2235 AIDS cases declared till March 1st 1993 by the Ministry of Health only 134 were adult persons. The study concerns 65 cases of AIDS in adults in order to find out the lung symptoms proportion as etiologic features, to settle the ways of transmission of HIV infection and to warn the romanian pneumologists on this problem. The study shows that in 56.9% of total cases, lung symptoms were noted and in 49.2% the lung disease revealed the AIDS. Out of the total number of 65 cases, 24.6% showed tuberculosis as a first disease, 12.4% lung pneumocystosis, 7.76 Kaposi syndrome with lung expression and 4.5% other pneumopathies.

AIDS-Related Opportunistic Infections↗

[Single-dose administration in the treatment with penicillin G (PG) and metronidazole (Me) in primary pulmonary abscesses (a preliminary study)].

The anaerobic bacteria play the main role in the etiology of the lung abscesses (Finegold, 1989). From this reason, the administration of the association PG and Me (endovenously or per os) gives a high healing rate in our country; 90.5%. The objective of this work was to study the influence of the drug-administration rhythm on the therapeutical results. The drugs were given once daily, several times daily, or in a combination of those 2 modalities. A lot of 38 patients hospitalized between 1.01.94-31.12.95 in the Institute of Pneumophthisiology, was divided in 3 groups: U (11 cases--28.9%), treated with PG: 5-10 mill and Me: 1.5-2 g in one endovenous perfusion, daily: M (18 cases--47.3%), treated with PG: 5-10 mill, one endovenous perfusion daily and Me: 1.5-2 g, 2-4 times daily: F (9 cases--23.8%), treated with both PG: 5-10 mill and Me: 1.5-2 g, 2-4 times daily. Cases with lung abscess and advanced neoplasia, hepato-renal or cardio-pulmonary insufficiencies, were excluded. The hospitalization period was 15-77 days, with an average of 38.3 +/- 26. The proportion of the therapeutical successes, estimated as the disparition of the clinical suppurative symptomatology and the reduction > or = 90% of the lesions and cavity surfaces on the chest X-ray, was for the group U: 90.9% (10 from 11 cases), for M: 94.4% (17 from 18 cases) and for F: 88.9% (8 from 9 cases), the difference being statistical non-significant.

Administration, Oral↗