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Biomedical subjects

O Benoit

Publications and source records attributed to O Benoit.

100 records · Page 6Linked to original sources

[Respiration and night sleep in children "at risk" for sudden and unexpected death (author's transl)].

Polygraphic recordings were used to study respiration and night sleep in 26 such children. These children, who were "at risk" for sudden and unexpected death, could be divided into two groups : near-miss (NM) (15 cases), and those who were brothers, sisters, or cousins of a child who had died suddenly and unexpectedly (8 cases), or had periodic respiration (RP) (3 cases). No significant differences were found between the groups in respiratory tests, except for a significantly lower RP rate in the NM group and an increase in number of isolated pauses. Sleep organization was similar in both groups, though there was a significantly higher rate of active sleep (SA) in the NM group more than 2 months old. The highest respiratory indices were noted in the extreme cases of a non-NM group (including 2 brothers of infants who had died unexpectedly). Treatment with Diphemanil methylsulfate (Prantal) reduced the number of SA and respiratory pauses of the NM infants less than 2 months old.

Female↗

Bright light during nighttime: effects on the circadian regulation of alertness and performance.

The present studies evaluated to what extent duration (all-night or 4-hour exposures) and timing of nocturnal bright light (BL) (beginning or end of the night) modulate effects on vigilance. The results showed that all-night BL exposure is able to alleviate the nocturnal decrements in alertness and performance. However, under certain circumstances, this continuous BL exposure may induce adverse effects on mood and finally reveal to be counterproductive. Shorter BL exposure (4 h) during nighttime helps improve mood and performance, although the effects of short BL pulses were less efficacious than all-night BL exposure. The latter part of the night appears the best time for using the alerting effect of BL. The immediate alerting effect of BL seems to be mediated by a global activation of the central nervous system.

Adult↗

Circadian aspects of motor activity in depressed patients.

Wrist motor activity was continuously monitored in 10 major unipolar depressed inpatients. Clinical state and motor activity parameters were studied. The data obtained at the beginning of the hospitalization, before the antidepressant treatment, were compared to chose found just before discharge. Time of day effect and subtypes of depression (endogenous versus non-endogenous) were considered. Motor retardation is related to both fluctuations of activity level and high number of 15 minute immobility epochs. Immobility parameters at night and during day were a good indicator of the severity of the depressive state. The temporal pattern of activity level was related to the subtype of depression.

Adult↗

Circadian rhythms (temperature, heart rate, vigilance, mood) of short and long sleepers: effects of sleep deprivation.

Seven long sleepers (LS) (sleep greater than or equal to 9 h) and seven short sleepers (SS) (sleep less than or equal to 7 h), aged 20 to 23 years, were selected among medical students. They measured their axillary temperature (T), heart rate (HR) and self-estimated their vigilance (V) and mood (M) every 4 h from awakening to bed time during a ten-day control span and during the two sleep deprived nights. Polygraphic sleep recordings were performed on 3 control days and recovery from 24 h (day sleep) or 36 h (night sleep) sleep deprivations. For the 4 variables (T, HR, V and M), group circadian patterns were analyzed by means of the cosinor method for the control span and after both types of sleep deprivation. The acrophases of the 4 variables clustered more in LS than in SS. The acrophases of V and M were found to be more closely related to the sleep/wake rhythm than those of T and HR. Sleep deprivation resulted in a large change of the circadian rhythms in LS but had little effect in SS as indicated by the non detection of most acrophases in LS and the persistence of such acrophases in SS. This difference might be explained by the large interindividual variability of changes induced by the sleep deprivation in LS. Moreover, day sleep recovery was more disturbed in LS than in SS.

Adult↗