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Biomedical subjects

O Bar-Or

Publications and source records attributed to O Bar-Or.

At least 55 records · Page 3Linked to original sources

Water and electrolyte replenishment in the exercising child.

This article reviews studies, mostly from the authors' laboratory, on children's sweating rates and composition, voluntary drinking patterns during prolonged exercise in the heat, taste perception of beverages, and the importance of fluid flavor and composition in preventing voluntary dehydration. Subjects were children, exposed for 90 to 180 min to intermittent bouts of cycling (45-50% maximal O2 uptake) in a climatic chamber (mostly at 35 degrees C, 40-50% relative humidity). There were five main findings: When given unflavored water ad libitum, children dehydrated progressively and their core temperature increased faster than in adults. When offered drinks with various flavors, children preferred grape to other flavors. When given grape-flavored water during intermittent exercise in the heat, children voluntarily drank 44.5% more than with unflavored water. When given grape-flavored carbohydrate-electrolyte solution, they voluntarily drank 91% more than with unflavored water. Finally, such consumption of carbohydrate-electrolyte solution was sufficient to prevent voluntary dehydration during 180-min intermittent exercise in the heat.

Adolescent↗

Effect of drink flavor and NaCL on voluntary drinking and hydration in boys exercising in the heat.

This study was intended to assess the influence of drink flavor and composition on voluntary drinking and hydration status in children exercising intermittently at 35 +/- 1 degrees C and 45-50% relative humidity. Twelve boys (9-12 yr) performed three 3-h identical sessions (four 20-min cycling bouts at 50% maximal O2 uptake followed by 25-min rest). One of three beverages (chilled to 8-10 degrees C) was assigned to each session in a Latin-square sequence: unflavored water (W), grape-flavored water (FW), and grape-flavored water plus 6% carbohydrate and 18 mmol/l NaCl (CNa). Drinking was ad libitum. Body weight, heart rate, rectal and skin temperatures, and thirst and stomach fullness perceptions were monitored periodically. Total intake was 610, 882, and 1,157 g in W, FW, and CNa, respectively (CNa-W and CNa-FW; P < 0.05). Hypohydration was observed with W (-0.65% body wt) and FW (-0.32% body wt), but drinking CNa resulted in slight overhydration (+0.47% body wt, CNa-W, CNa-FW; P < 0.05). Other physiological and all perceptual variables were insignificantly different among trails. In conclusion, while flavoring of water reduces children's voluntary dehydration, further addition of 6% carbohydrates and 18 mmol/l NaCl prevents it altogether.

Body Temperature Regulation↗

Cocontraction and phasic activity during GAIT in children with cerebral palsy.

Simultaneous activity of agonist and antagonistic muscles during a task is known as cocontraction. The primary aim of the present study was to use a cocontraction index (CI) to quantify differences in EMG activity between a group of CP and control children at two different walking speeds. The secondary aim was to compare the amount of time the muscles were activated ("on" thresholds) between the groups. Seventeen subjects volunteered for the study. One group consisted of 9 (7M, 2F) children with CP (age 12.7 +/- 2.8 years, mean +/- SD). The second group consisted of 8 able-bodied controls (7M, 1F). The discontinuous submaximal treadmill walking protocol had two 4min stages at 0% gradient. Speeds selected were 3 km.h-1 and 90% of the pre-determined fastest walking speed (FWS). Two sites of CI were measured from the EMGs of tibialis anterior and soleus (leg) and vastus lateralis and hamstrings (thigh). Significantly (p < 0.05) higher CI values were noted for the CP subjects compared to the controls, irrespective of speed or cocontraction site and there was a significant (p < 0.05) increase in CI values with increased walking speed for both CP and control subjects. Phasic analyses for 5% max EMG and 10% max EMG "on" thresholds demonstrated significant (p < 0.05) main effects for group (CP subjects had a longer time period of muscle activation than controls) and speed (muscles were active longer at 90% FWS than 3 km.h-1). The precise mechanisms by which cocontraction contributes toward abnormal gait and wasted mechanical energy require further research incorporating both electromyographic and kinematic analysis.

Adolescent↗

The young athlete: some physiological considerations.

Child athletes have a low ability to generate high-intensity anaerobic power and their local muscular endurance is low compared with that of adult athletes. This is reflected in children's low performance in short and long sprints, jumps and throwing events. On the other hand, children achieve steady-state at the start of intense exercise and recover more quickly than adults following intense exercise. A practical implication is that, during high-intensity interval training, children may need shorter resting periods than adults. Children take longer than adults to acclimate or acclimatize to heat. Upon transition to a warmer climate, their daily training volume and intensity should therefore be curtailed more so than in adults. Compared with adults, children thermoregulate less effectively during dehydration. Adequate fluid replenishment is therefore paramount for the child athlete. Flavouring the fluid is one means of enhancing young athletes' drinking volume. It is possible that adding sodium and chloride to the drink will further enhance drinking volume.

Adolescent↗

Children's perceptual responses to ingesting drinks of different compositions during and following exercise in the heat.

Twelve 9- to 12-year-old children performed four exercise-in-the-heat trials (35 degrees C, 45% RH), which differed in the fluids consumed. In each trial, subjects were kept euhydrated while cycling one 20-min and two 15-min bouts at 50% peak VO2 followed by a 90% peak VO2 bout until exhaustion. Thereafter, they could drink ab libitum while resting. One drink was water, and the other three drinks had 6% CHO with different Na+: 0, 8.8, and 18.5 mEq.L-1. All drinks had the same grape flavor. The perceived thirst was similar among trials and it did not increase while subjects were exercising. On average, subjects felt their stomach "somewhat full" with no difference among drinks. Thermal sensations, RPE, and overall comfort were similar among trials. During a 30-min recovery, volume intake was similar among drinks (201 +/- 27 ml). In conclusion, the drink composition did not affect perceptual responses to drinking while euhydrated children exercised in the heat, nor did it affect drinking behavior during recovery.

Analysis of Variance↗

Climate-related corrections for improved estimation of energy expenditure from heart rate in children.

The purpose of this study was to determine the relationship between children's heart rate (HR) and climatic heat stress at several O2 uptake (Vo2) levels and to construct equations and nomograms for an improved estimation of energy expenditure (EE) from HR monitoring. On four occasions 12 boys and 8 girls (8-11 yr) cycled for 5 min each at 35, 55, and 75% of peak Vo2 (random order), with rest periods in between, in a climatic chamber. The randomly assigned conditions were 22 degrees C dry bulb temperature, 50% relative humidity (RH); 28 degrees C, 55% RH; 32 degrees C, 52% RH; or 35 degrees C, 58% RH. HR and Vo2 were determined during the final 2 min of rest and exercise bouts. HR measured at a dry bulb temperature (T) (HRmeas) was then related to a HR at 22 degrees C that would have been expected to occur at an identical Vo2 (HRcalc22) by using individual 22 degrees C HR-Vo2 regression lines. HRcalc22 could be estimated from HRmeas.[1.175032-(0.007956.T)], with a mean error of prediction for the entire group < 1.5 beats/min for each temperature. The following conclusions were drawn: 1) children's HR at a given Vo2 increases linearly with ambient temperature at 22-35 degrees C, 50-60% RH; and 2) HR can be corrected for the influence of climate in groups of children resting and exercising at the above conditions, thereby reducing the error of estimating EE from HR.

Child↗

The reliability and repeatability of the blood glucose response to prolonged exercise in adolescent boys with IDDM.

OBJECTIVE: To determine the intrasubject reliability and repeatability of the blood glucose response to prolonged exercise in adolescents with insulin-dependent diabetes mellitus (IDDM) when pre-exercise meal, exercise, and insulin regimens are kept constant. RESEARCH DESIGN AND METHODS: Nine IDDM adolescent boys with diabetes duration of 9.7 +/- 4.8 years participated in two testing sessions 5-17 days apart. Carbohydrate intake, subcutaneous insulin injections, exercise bouts, and their timing were identical in both sessions. Exercise started 1 h after breakfast and consisted of six 10-min cycling bouts at moderate intensity (heart rate 145-150 beats/min), separated by 5-min rest periods. During rest periods, blood samples for glucose were taken and a supplemental carbohydrate beverage was consumed. Subjects were asked periodically to guess their own blood glucose levels. RESULTS: Intersession plasma glucose levels for each time period from the start of exercise to the end of the final recovery period were unchanged between sessions (P > 0.05) and highly correlated (r = 0.88 to r = 0.96, P < 0.01). The intraclass correlation for plasma glucose was 0.95. Decreases in plasma glucose from the start of exercise to the end of exercise were, at most 5 mmol/l, and intersession decreases did not differ significantly (P > 0.05). One subject experienced hypoglycemia. The decrease in plasma glucose did not differ significantly between fair and poor glycemic control (glycosylated hemoglobin < or = 10% and > 10%, respectively). Subjects markedly underestimated their blood glucose levels when they were high, but their guesses were closer to the measured values at lower levels. CONCLUSIONS: --Intersession observations demonstrated that the intrasubject blood glucose responses to prolonged moderate-intensity exercise were reliable and repeatable when pre-exercise meal, exercise, and insulin, regimens were kept constant. This is an important finding for implementing and evaluating educational strategies for improving the metabolic control associated with prolonged exercise, as well as for future research on means for preventing exercise-induced hypoglycemia.

Adolescent↗

The young athlete with chronic disease.

Iron deficiency anemia can affect athletic performance. Physicians must be wary of the at risk population, namely vegetarians, female adolescents, and long distance athletes. Particular attention must be paid to nutritional intake and to the use of nonsteroidal anti-inflammatory agents and aspirin.

Adolescent↗

Drink composition and the electrolyte balance of children exercising in the heat.

Twelve 9- to 12-year-old children (6 boys, 6 girls) performed four exercise-in-heat (35 degrees C, 45% RH) trials which differed in the composition of the fluids they drank. In each trial, subjects cycled for one 20-min and two 15-min bouts at 50% peak VO2 with 10-min rest periods in between. In a fourth bout, they cycled at 90% peak VO2 until exhaustion. Drinks had the same grape flavor and were assigned in a double-blind design and in a Latin-square order. Subjects drank 7 ml.kg-1.h-1 to keep them euhydrated. Three of the drinks had 6% carbohydrates (CHO), with different [Na+]: 0, 8.8, 18.5 mmol.l-1 and one drink had neither CHO nor Na+ (WATER). Among drink trials, there were no differences in the increase in rectal temperature, HR, or performance time to exhaustion. Despite the larger Na+ deficit induced by the Na(+)-free drinks compared with the Na+ drinks (11.8 +/- 1.4 vs 5.7 +/- 0.9 mmol.h-1), neither plasma [Na+] nor osmolality were affected. These results suggest that electrolyte, as in the above conditions, did not affect electrolyte balance, thermoregulatory responses, or aerobic performance of children exercising in the heat. The greater Na+ deficit induced by ion-free drinks was of minor biological importance.

Blood Glucose↗

Hypohydration during exercise in children: effect on thirst, drink preferences, and rehydration.

This study examined changes in children's thirst and drink preferences during exercise-induced hypohydration and their spontaneous rehydration during a 30-min recovery. Twenty-four 9- to 13-year-old children (14 females, 10 males) participated in four intermittent 90-min cycling sessions in the heat (35 degrees C, 20% relative humidity); the sessions differed in the drinks the children were sampling (apple, orange, water, and grape). Thirst and drink preferences were assessed (analog and category scales) while children dehydrated up to about 0.76% of their initial body weight. During 90 min dehydration, there was an increase in thirst intensity for all drinks. The grape was the preferable drink throughout the dehydration phase, but its desirability did not increase as much as the desirability of the orange, apple, and water drinks. During the 30-min recovery, most subjects rehydrated spontaneously, exceeding baseline levels by 0.76 +/- 0.15% (M +/- SEM) for grape, 0.40 +/- 0.15 for apple, 0.71 +/- 0.18 for orange, and 0.48 +/- 0.16 for water. Although full rehydration was achieved with all drinks, the magnitude of rehydration was statistically greater with grape and orange than water and apple (p < .05). It was concluded that mild hypohydration during exercise increased children's thirst and drink desirability. In general, spontaneous overshoot of fluid consumption occurred during recovery.

Adolescent↗

Response to rest and exercise in the cold: effects of age and aerobic fitness.

The aim of this study was to determine whether age-related differences in the response to cold exposure are due to aging per se or are caused by a reduced maximal oxygen uptake (VO2max) often observed with aging. Three groups of men, 8 young adults (YA), 8 well-trained seniors (TS), and 11 untrained seniors (US), were tested on a cycle ergometer in thermoneutral (22 degrees C) and cold (5 degrees C) conditions during rest and then during exercise (approximately 50 W). In the thermoneutral conditions, 10 min of rest were followed by 10 min of exercise. After 60 min of rest, subjects entered the cold where 30 min of rest were followed by 30 min exercise. The subjects of the three groups had similar body surface area and subcutaneous fat thickness. It was found that rectal temperature (Tre) decreased during rest in the cold and continued to decrease at a higher rate during exercise in TS and US but not in YA. The mean skin temperature was similar in all the groups, except for the thigh temperature, which was lower in YA than in TS and US. Oxygen uptake (VO2) increased during cold, significantly more so at rest than during exercise. YA displayed the highest VO2 during the first 10 min of rest in the cold, whereas TS displayed the highest VO2 during exercise in the cold. Neither aging nor VO2max appeared to affect thermal comfort or cold sensation.(ABSTRACT TRUNCATED AT 250 WORDS)

Adult↗

The effects of indomethacin on refractoriness following exercise both with and without a bronchoconstrictor response.

Repeated exercise tests demonstrate refractoriness to the development of exercise-induced asthma (EIA). It is unclear whether it is the initial exercise per se or the resulting bronchoconstriction that causes the attenuated response to the second exercise challenge. This study was designed to determine whether the reported blocking of the refractory period by indomethacin requires a significant bronchoconstriction following the primary exercise challenge. Thirteen asthmatic teenagers (aged 12-16 yrs) were tested on four visits. Each visit included two 7 min treadmill exercise challenges at 80% maximum heart rate, separated by a 30 min rest. Conditions for the second exercise challenge (Ch2) were always thermoneutral (20-22 degrees C and 25-35% relative humidity (RH); whilst challenge one (Ch1) was completed twice in thermoneutral and twice in warm-humid breathing conditions (33-35 degrees C and 90-95% RH). A pretreatment for 3 days in a double-blind design with either placebo or indomethacin was completed. Forced expiratory volume in one second (FEV1) was measured before and repeatedly following each challenge. The % fall in FEV1 following Ch1 of the placebo thermoneutral trial was taken as reference. "Percent protection" at each visit was expressed as the decrease in EIA following Ch2, compared to reference. Warm-humid breathing reduced the EIA post Ch1 by 75%, whilst providing similar protection to thermoneutral conditions. Indomethacin had no significant effect on EIA after Ch1, but reduced "percent protection" for both warm-humid (from 67 to 16%) and thermoneutral (from 70 to 26%) conditions.(ABSTRACT TRUNCATED AT 250 WORDS)

Adolescent↗

Nutritional requirements of young soccer players.

The general dietary needs of the young soccer player appear to be similar to those of the adult soccer player. There are, however, several age- and maturation-related differences. Compared with adults, children's daily recommended protein intake (per kg body mass) is higher; during exercise, children's muscles rely more on fat than on carbohydrates, but it is not clear whether young soccer players need higher dietary fat; calculated per kg body mass, the metabolic demands of walking and running are considerably higher in children; and during dehydration, children's core temperature rises faster, which calls for stricter enforcement of hydration. To increase fluid palatability, drinks should be flavoured, according to the child's individual preference. The efficacy and safety of 'carbohydrate loading' have not been studied in children.

Child↗

Relationships among nutritional status and skeletal and respiratory muscle function in cystic fibrosis: does early dietary supplementation make a difference?

Relationships among nutritional status and skeletal and respiratory muscle function were examined in 16 children with cystic fibrosis (CF) and mild lung disease (FEV1 95 +/- 16% predicted). Subjects were randomly assigned to receive (or not) noninvasive nutritional supplementation at 25% of normal energy recommendations for 6 mo. Skeletal muscle strength and power were similar to those of healthy children as were respiratory muscle strength and endurance. Stepwise-regression analysis indicated that changes in skeletal muscle strength and energy intake correlated significantly with growth [weight (kg) = 1.90 - 0.60 (Tanner Stage) + 0.49 (maximum voluntary strength (Nm) + 0.03 (energy intake, % RNI), r = 0.76, P < 0.05], though body composition, protein biochemistry, muscle power, respiratory muscle strength, and use of dietary supplements did not. Thus, changes in skeletal muscle strength may be a functional index of changes in nutritional status in CF. Dietary supplementation per se was not associated with functional improvement.

Adolescent↗

Muscle performance and gross motor function of children with spastic cerebral palsy.

The purpose of this study was to determine whether, and to what extent, performance on a measure of motor function (Gross Motor Function Measure, GMFM) was related to the physiological fitness of children with cerebral palsy (CP). Two elements of physiological function were measured: aerobic power and anaerobic power of the arms and legs. 15 boys and eight girls aged between seven and 13.9 years with spastic CP participated in the study. There was a good relationship between the standing and walking, running and jumping sub-sections and the total score of the GMFM on one hand, and anaerobic capacity of the legs on the other. However, the relationships for the arms were limited, indicating that the GMFM is not a suitable tool for providing information about aerobic fitness in children with CP, or about anaerobic power of the arms.

Adolescent↗