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Biomedical subjects

O B Adler

Publications and source records attributed to O B Adler.

At least 19 recordsLinked to original sources

[Computed tomography in the diagnosis of popliteal artery entrapment syndrome].

Popliteal artery entrapment syndrome (PAES), a rare cause of lower limb ischemia, is due to an anomalous relationship between the popliteal artery and the gastrocnemius muscle in the popliteal fossa. Hypertrophy of the muscle, or its anomalous insertion, can displace or compress the artery, leading to stenosis or obstruction. It is clinically manifested by intermittent claudication and most often occurs in young, healthy men. Arteriography is the method of choice to demonstrate vascular lesions, but it can only visualize change in the course of vessels or intrinsic lesions. Due to its high spatial and density resolution, CT scan can differentiate between bony structures, vessels, muscles, and fatty tissue in the popliteal fossa. It is therefore a very useful supporting examination in PAES and can demonstrate whether or not stenosis or occlusion of the artery results from causes outside the artery itself.

Arterial Occlusive Diseases↗

[Breast biopsy of nonpalpable lesions after mammography-guided wire localization].

Mammography is used increasingly for diagnosis and screening. Its advantage is its ability to discover very small and often nonpalpable mammary lesions. While its sensitivity in detecting pathological changes in the breast is high, differentiation between benign and malignant lesions is less precise, so biopsy is necessary. To ensure removal of the entire lesion with minimal damage to breast tissue, precise localization is mandatory. The accepted technique is the needle-wire method. 39 of 167 biopsies guided by mammography performed during 3 years for nonpalpable lesions detected by mammography were malignant. In 24 of them the histological diagnosis was atypical epithelial proliferation, considered a transition to carcinoma.

Biopsy↗

Palmar hyperhidrosis CT guided chemical percutaneous thoracic sympathectomy.

Palmar hyperhidrosis or excessive sweating of the hands causes, to those affected, emotional and physical disturbance and impediment in professional and social life. The cause is unknown. Sweat glands are innervated by the sympathetic chain of the autonomous nervous system. The center of sympathetic regulation of the upper extremities is located between the segments of D.2-D.9 of the spinal cord. Accepted treatment consists of surgery aimed to excise the third thoracic sympathetic ganglion. Besides the surgical procedure as such, and its complications, there are complications inherent to the excision of the ganglion. These are Horner's syndrome, compensatory sweating in other parts of the body, and recurrence of sweating. CT guided chemical percutaneous thoracic sympathectomy presents an alternative, which in the event of failure does not prevent ensuing surgery. The preliminary experience with this procedure in 50 patients is presented and discussed.

Adolescent↗

Invasive lobular carcinoma. Mammographic pattern.

A retrospective study was done on 107 histologically proven cases of invasive lobular carcinoma which represent about 11.5% of the total of 934 cases of cancer of the breast. Age, breast parenchyma pattern and morphology, and radiological signs of malignancy were tabulated and correlated with the same data in ductal carcinoma. The number of false negative cases was almost twice as high as in ductal carcinoma type (19% versus 10%). In the majority of cases the patients presented a glandular or dense type of parenchyma pattern, which reduced the internal visibility. Besides spiculated masses, relatively subtle signs of malignancy, as asymmetric density and architectural distortion were relatively more frequently represented than in the ductal type of breast carcinoma. No clear-cut radiological criteria could be found pointing toward the underlying histology. Discreet clinical signs in younger patients with glandular or dense breast should alert the radiologist to the possible presence of this type of carcinoma. Due attention should be warranted to these less conspicuous signs of malignancy such as asymmetric density and architectural distortion.

Adult↗

Nonocclusive ischaemic bowel disease in patients on chronic haemodialysis.

Six patients with chronic renal failure on longstanding haemodialysis are presented, in whom nonocclusive bowel ischaemia occurred as a rare complication of their underlying disorder. Factors implicated in the development of bowel ischaemia in these patients are chronic constipation resulting in increased intraluminal pressure on the bowel wall, premature and progressive arterial disease and bouts of hypotension accompanying the haemodialysis procedure. Contrast studies of the bowel and computed tomography examination can suggest the diagnosis, but angiography alone provides the exact answer in demonstrating nonocclusive mesenteric ischaemia. In patients with chronic renal failure and longstanding dialysis presenting with abdominal symptoms this diagnosis should be considered.

Aged↗

Mammographic wire-guided biopsies in non-palpable breast lesions.

The use of mammography, both for diagnostic and screening purposes, is steadily increasing. It is a very sensitive examination method; findings such as an ill-defined or spiculated mass, clustered, irregular and dense microcalcifications, asymmetric densities or architectural distortion, are suggestive of malignancy. These findings are often not specific enough to make an unequivocal diagnosis of malignancy, and they are frequently not palpable. The presence of clinically occult, but mammographically present findings warrants biopsy to determine their histological nature. In order to avoid unnecessarily large biopsies and to assure the removal of the suspicious portion of the breast, precise localization in necessary, guided by mammography. Using a needle-hookwire method, 87 biopsies were done for non-palpable breast lesions detected among 3,196 mammographies performed. Experience with this method and the results show that 17 patients, i.e. every fifth biopsy, had a malignancy. In 5 patients out of 17, the findings proved to be in situ carcinoma. In another group of 17 women the biopsy result was atypical epithelial proliferation, considered to be a transitional phase of in situ carcinoma.

Adult↗

Reevaluation of transthoracic fine needle aspiration biopsy in diagnosing superior vena cava syndrome.

Superior vena cava syndrome has various aetiologies but in the majority of cases it is caused by a malignant mass. Assessment of the underlying pathology as rapidly and reliably as possible is very important for proper therapy management. Dynamic computed tomography examination of the chest can differentiate patients in whom superior vena cava obstruction is caused by a mass, from those with a vascular aetiology. In patients with a mass, fine needle aspiration biopsy guided by the computed tomographic examination may provide cytological diagnosis in a fast and well tolerated manner.

Adult↗

CT guided transgluteal fine needle aspiration biopsy.

CT is a suitable method for evaluation of local recurrence of rectal carcinoma after abdomino-perineal resection, as the presence of a soft tissue mass in the presacral area may be due to either residual changes from the previous surgery, or recurring disease. CT guided fine needle aspiration biopsy with a transgluteal approach was a relatively simple and fast procedure for obtaining cytological proof on the nature of the lesion in 7 out of 9 patients.

Biopsy, Needle↗

Pseudocyst in splenic hilus with splenic vein thrombosis. Case presentation and review.

Pseudocyst of the pancreas involving the spleen is a rare event; occlusion of splenic vein is even rarer. The mortality rate of these complications is high and therefore necessitates early diagnosis. Nuclear medicine, ultrasound and computed tomography are helpful, but definitive diagnosis is done by selective celiac or splenic artery arteriography. A case of splenic vein thrombosis due to pancreatic pseudocyst is presented and the literature on splenic involvement by pseudocyst is reviewed.

Adult↗

Radiology in war.

Explore the source record for details and available documents.

Abdominal Injuries↗

Fine-needle aspiration biopsy of mediastinal masses: evaluation of 136 experiences.

Experience with 136 fine-needle aspiration biopsies of mediastinal masses performed in 84 patients is reviewed. Biopsies were performed in all compartments of the mediastinum regardless of age. The biopsy technique included a 22-gauge needle with limitation of needle passes to an arbitrary number of three. The biopsy procedure was guided by either fluoroscopy or computed tomography (CT); guidance by CT is advantageous in the region of the thoracic inlet, hilum, and middle mediastinum, in small mediastinal masses, and in patients with superior vena cava syndrome. In 67 patients (79.7%) a specific cytologic diagnosis was obtained; in seven patients (8.3%), despite the presence of cells in the cytologic specimen, diagnosis could not be assessed. In the other 10 patients (11%), the samples obtained did not contain any cells. Morbidity was low: Light complications occurred in 15 patients (16.6%); drainage of pneumothorax was necessary in only three more. Bronchoscopy provided histology in three patients out of 12, mediastinoscopy established histologic diagnosis in 10 patients out of 16; surgery to remove the mass was performed in 38 patients. It is believed that fine-needle aspiration biopsy should be the first invasive procedure in the workup for diagnosing the nature of a mediastinal mass.

Adolescent↗

Radiological aspects of Behçet disease.

The systemic manifestations of Behçet disease were evaluated retrospectively in 45 patients. Twenty-seven patients underwent radiographic examination. Twenty-two examinations (64.7%) showed positive but nonspecific findings, most of them involving the vascular tree. The roentgen diagnosis of Behçet disease will be influenced by the dermatologic and ophthalmologic findings.

Adolescent↗

Percutaneous transluminal angioplasty of the iliac and lower limb vessels: one year's experience.

Percutaneous transluminal angioplasty (PTA) based on the angiographic technique consists of the use of fluoroscopically monitored special catheters to relieve stenotic segments of recanalize occlusive lesions of the vascular tree. In the course of one year, 192 patients were evaluated angiographically for peripheral vascular disease, of whom 32 were selected for PTA. Twelve patients had PTA for the iliac vessels with a success rate of 83%; 20 patients had PTA for the lower limb arteries with a 60% success rate. The end results depended on the nature of the underlying lesion, with totally occluded arteries having the poorest outcome. The method and the results are described, and the value of the procedure, as reflected in the literature and from our experience, is discussed.

Adult↗