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Biomedical subjects

O Alexandersen

Publications and source records attributed to O Alexandersen.

5 recordsLinked to original sources

[Lung cancer].

INTRODUCTION: The aim of this study was to examine our lung cancer patients, particularly their smoking habits and survival rates. MATERIAL AND METHODS: Information was recorded prospectively on 219 patients seen in our hospital from 1987 to 1992. RESULTS: Average age was 65.5 years (39-85 years). 27% were female. 9% were 49 years or younger, 13 men and seven women. Only six patient (3%) were non-smokers, 77% were smokers and 20% ex-smokers. 52 patients (24%) had small cell lung cancer (SCLC) and 167 (76%) non-small cell lung cancer (NSCLC). All six non-smokers had adenocarcinoma (two bronchioloalveolar cell carcinoma). 63% had advanced disease (stage IIIB and IV or small cell cancer, extensive disease). Only 22 patients (10%) were alive at five years: 19 patients with NSCLC who had got surgical treatment, one patient with NSCLC (stage IIIB) who had recieved radiotherapy, and two patients with SCLC, limited disease, treated with chemo- and radiotherapy. The surgically treated patients (23%) had a five-year survival of 50% (17/33) at stage I, 33% (2/6) at stage II, and none (0/7) at stage IIIA. INTERPRETATION: This poor outlook for patients with lung cancer and the fact that there are few non-smokers among them, tell us that the major emphasis must be on prevention.

Adenocarcinoma↗

[Pulmonary damage caused by ski waxing].

It is well known that inhalation of pyrolysis products of perfluorinated hydrocarbons (e.g. Teflon) may result in polymer-fume fever and even pulmonary oedema. A new type of ski wax has recently been introduced, a powder consisting of low-molecular perfluorinated hydrocarbons. We report a case history of a man who developed an attack of polymer-fume fever and pulmonary oedema after smoking cigarettes contaminated with this ski wax. Inhalation of vapour from ski waxes melted at low temperatures may also be harmful to the lungs.

Adult↗