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PubMed1988

Automatic piercing spinhaler (Halermatic): a comparative study.

Fifty patients, 27 females and 23 males with a mean age of 30 years and a history of chronic asthma, were studied during treatment with cromolyn sodium administered via the standard spinhaler and a new automatic piercing spinhaler, Halermatic. The study period consisted of a baseline period of 3 weeks (spinhaler use) and an 8-week period of Halermatic use. In the final analysis of results, it was noted that fewer inhalations (P less than .001) were needed to empty the cromolyn Spincaps with the Halermatic and a higher number of patients (61%) preferred the Halermatic over the Spinhaler.

Adolescent↗

PubMed1986

Anaphylactoid and systemic reactions following saline enema administration. Six case reports.

This report describes six children with spina bifida who have experienced a total of 13 episodes of generalized hives, angioedema and in two cases, anaphylactoid reactions immediately following saline enema infusions. The enemas were administered using a kit comprised of a plastic bag, tubing, and rectal end-piece. The reactions always occurred with the first use of new kits. A third child developed a systemic reaction with only the rectal end-piece in situ and without infusion of fluid. An in-hospital challenge using a new end-piece in one patient, who was clinically the most sensitive, produced an acute anaphylactoid reaction implicating the end-piece as the most likely source of the problem. The definitive mechanism(s) of the reactions and the agent(s) responsible for them presently remain unknown.

Anaphylaxis↗