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Biomedical subjects

Nikos Paragios

Publications and source records attributed to Nikos Paragios.

4 recordsLinked to original sources

Shape registration in implicit spaces using information theory and free form deformations.

We present a novel, variational and statistical approach for shape registration. Shapes of interest are implicitly embedded in a higher-dimensional space of distance transforms. In this implicit embedding space, registration is formulated in a hierarchical manner: the Mutual Information criterion supports various transformation models and is optimized to perform global registration; then, a B-spline-based Incremental Free Form Deformations (IFFD) model is used to minimize a Sum-of-Squared-Differences (SSD) measure and further recover a dense local nonrigid registration field. The key advantage of such framework is twofold: (1) it naturally deals with shapes of arbitrary dimension (2D, 3D, or higher) and arbitrary topology (multiple parts, closed/open) and (2) it preserves shape topology during local deformation and produces local registration fields that are smooth, continuous, and establish one-to-one correspondences. Its invariance to initial conditions is evaluated through empirical validation, and various hard 2D/3D geometric shape registration examples are used to show its robustness to noise, severe occlusion, and missing parts. We demonstrate the power of the proposed framework using two applications: one for statistical modeling of anatomical structures, another for 3D face scan registration and expression tracking. We also compare the performance of our algorithm with that of several other well-known shape registration algorithms.

Algorithms↗

Particle filters, a quasi-Monte-Carlo-solution for segmentation of coronaries.

In this paper we propose a Particle Filter-based approach for the segmentation of coronary arteries. To this end, successive planes of the vessel are modeled as unknown states of a sequential process. Such states consist of the orientation, position, shape model and appearance (in statistical terms) of the vessel that are recovered in an incremental fashion, using a sequential Bayesian filter (Particle Filter). In order to account for bifurcations and branchings, we consider a Monte Carlo sampling rule that propagates in parallel multiple hypotheses. Promising results on the segmentation of coronary arteries demonstrate the potential of the proposed approach.

Algorithms↗

Gradient vector flow fast geometric active contours.

In this paper, we propose an edge-driven bidirectional geometric flow for boundary extraction. To this end, we combine the geodesic active contour flow and the gradient vector flow external force for snakes. The resulting motion equation is considered within a level set formulation, can deal with topological changes and important shape deformations. An efficient numerical schema is used for the flow implementation that exhibits robust behavior and has fast convergence rate. Promising results on real and synthetic images demonstrate the potentials of the flow.

Algorithms↗

A level set approach for shape-driven segmentation and tracking of the left ventricle.

Knowledge-based segmentation has been explored significantly in medical imaging. Prior anatomical knowledge can be used to define constraints that can improve performance of segmentation algorithms to physically corrupted and incomplete data. In this paper, the objective is to introduce such knowledge-based constraints while preserving the ability of dealing with local deformations. Toward this end, we propose a variational level set framework that can account for global shape consistency as well as for local deformations. In order to improve performance, the problems of segmentation and tracking of the structure of interest are dealt with simultaneously by introducing the notion of time in the process and looking for a solution that satisfies that prior constraints while being consistent along consecutive frames. Promising experimental results in magnetic resonance and ultrasonic cardiac images demonstrate the potentials of our approach.

Algorithms↗