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Biomedical subjects

Neil S Sadick

Publications and source records attributed to Neil S Sadick.

41 records · Page 3Linked to original sources
PubMed2002

A dual wavelength approach for laser/intense pulsed light source treatment of lower extremity veins.

BACKGROUND: Consistent reproducible aesthetic results are a desired component of laser/intense pulsed light (IPL) treatment of lower extremity blood vessels. In this regard, shorter wavelengths may be used to treat fine red telangiectases, whereas longer wavelengths may be used to treat larger diameter blue venulectasia and small reticular veins. OBJECTIVE: The purpose of the present study was to demonstrate that a bimodal wavelength approach to laser/IPL source treatment for lower extremity vessels up to 8 mm in diameter produces results superior to previously described photothermolytic approaches for eradication of unwanted lower extremity blood vessels. METHODS: Fifty female patients (mean age, 37 years) were treated in a private practice setting with class I-III red telangiectasia, blue venulectasia, and reticular veins (0.1-4.0 mm in diameter) on the inner or outer thighs. A combined approach of laser/IPL treatment was used; patients had up to 3 treatments at 6-week intervals on a 5-cm2 surface area of vessels with the use of an IPL source wavelength of 550 nm, fluence of 40 J/cm2, for treatment of red telangiectases less than 1 mm in diameter, while a 1064-nm Nd:YAG laser at a fluence of 140 J/cm2 was used to treat venulectases and reticular vessels that were 1.0 to 4.0 mm in diameter. Results were analyzed by macrophotographic imaging, double-blinded observer evaluation, optical chromatography, and a patient evaluation scale. RESULTS: An average of 2(1/2) patient sessions produced significant clearing (75%-100%) in 80% of patients. The mean erythema index showed significant lightening (35.3+dl) in the study population. Finally, 76% of patients reported great satisfaction with the treatment results. CONCLUSION: A bimodal wavelength approach utilizing both short and long wavelengths produces significant clearing of the variably colored, multiple-diameter/depth array of vessels, which commonly presents a therapeutic challenge to the vascular laser surgeon.

Adult↗
PubMedDate not supplied

The cosmetic use of botulinum toxin type B in the upper face.

Facial wrinkles involving the forehead, glabellar, and/or periorbital regions are a common esthetic problem and are directly related to overactivity of the underlying facial musculature. For instance, the development of glabellar wrinkles is related, at least in part, to the dynamics of the underlying procerus, corrugator supercilii, and orbicularis oculi muscles. Facial lines are considered problematic because they produce the appearance of aging. In some cases, they can also be misinterpreted as manifestations of negative emotions (eg, anger, anxiety, sadness), fatigue, or stress. In recent years, botulinum toxin injections have become one of the most popular therapies for the treatment of hyperfunctional facial lines. After injection, the toxin acts to paralyze or weaken facial mimetic muscles. This reduces or eliminates the appearance of wrinkles and is extremely safe.

Botulinum Toxins↗
PubMedDate not supplied

Photorejuvenation with intense pulsed light: results of a multi-center study.

This multi-center study evaluating the role of Intense Pulsed Light (IPL) in the non-ablative rejuvenation of Type I and Type II photoaged skin study was conducted in order to evaluate the clinical efficacy and safety of using IPL in treating clinical indications associated with photoaged skin. Ninety-three patients of Fitzpatrick skin phenotypes I-III, Fitzpatrick Wrinkle Classes I-II, and Elastosis Scores 1-6 were enrolled in the study. Up to five treatments were performed at 4-week intervals with follow-up visits at 4 and 6 months after the last treatment. Patients received full-face treatments using the recommended parameters of the Quantum SR/HR (Lumenis Ltd.) with the 560 or 640 nm cutoff filter. Parameters of elastometry, physicians' evaluation of the Elastosis Score ('W/ES'), and global improvement as well as patient satisfaction were analyzed. Results showed that the average Fitzpatrick W/ES improved significantly (p<0.001) by 1.39 and 1.32 units at the 4 and 6 months follow-ups, respectively; an improved W/ES evaluation was recorded for 82% and 75% of the patients at each of these time points. In conclusion, IPL treatment is an effective non-invasive, non-ablative method for rejuvenating photoaged skin with minimal adverse events, no downtime, excellent long-term results, and a very high measure of patient satisfaction.

Adult↗
PubMedDate not supplied

Enhanced full-face skin rejuvenation using synchronous intense pulsed optical and conducted bipolar radiofrequency energy (ELOS): introducing selective radiophotothermolysis.

BACKGROUND: The authors previously reported their experience achieving non-ablative skin enhancement with serial, full-face, intense pulsed light treatments in a large series of patients. A new method for skin renewal electro-optical synergy (ELOS), which combines intense pulsed optical energy and conducted bipolar radiofrequency (RF) energy into a single pulse, has been recently introduced. Intense pulsed optical energy and bipolar RF energy have been used in dermatologic surgery for many years; however, this study represents the therapeutic impact of the combined energies. OBJECTIVE: The authors report their experience using an ELOS system (Aurora SR, Syneron, Yokneam, Israel) on 108 consecutive patients treated with a series of full-face procedures. METHODS: Patients received 5 full-face treatments every 3 weeks. Each treatment consisted of 1 to 8 full-face and segmental passes. The number of passes, specific wavelength of pulsed optical energy, and RF energy were determined by the patient's skin type, dyschromia, wrinkle pathology, and presence of a tan. A total of 540 treatments were performed on 108 subjects. All patients had pre- and post-procedural photographs. Results were assessed by double-blinded physician photographic evaluation and patient satisfaction scales. RESULTS: Overall skin improvement was rated at 75.3%. Overall average wrinkle improvement was 41.2%, with an average Class 1 wrinkle improvement of 64.7%, Class 2 wrinkle improvement of 38.6%, and Class 3 wrinkle improvement of 20.4%. Improvement in skin laxity was rated at 62.9%. Skin texture was reported to improve 74.1%. Improvement in the appearance of pore size was rated at 65.1%. Average improvement in erythema and telangiectasia was 68.4%. Average improvement in hyperpigmentation and dyschromia was 79.3%. Overall patient satisfaction was 92%. The overall minor complication rate, including blistering, crusting, and stripping was 8.3%, and the major complication rate was less than 1%. One small, depressed nasal scar was observed in one patient. CONCLUSIONS: This study demonstrates the safety and efficacy of a new technology using combined optical and conducted bipolar RF energies for noninvasive skin rejuvenation. The results show improvement in wrinkle reduction and amelioration of erythema, telangiectasia, and hyperpigmentation comparable to that reported for other intense pulsed light technologies.

Adult↗