Biomedical subjects

N el-Hassan

Publications and source records attributed to N el-Hassan.

3 recordsLinked to original sources

PubMed2000

High frequency ventilation.

High frequency ventilation (HFV) is a general term that refers to a family of mechanical ventilation techniques that involves ventilator rates that are supraphysiological (more than 60 breaths/minute), and utilizes tidal volumes that are equal or less than the anatomical dead space of the airways. This paper is a review of the different HFV techniques, along with the mechanisms of oxygenation and ventilation, the clinical applications, and management strategies for different disease entities, and possible complications of HFV.

Animals↗

PubMed2000

High frequency ventilation in five different neonatal pathologies.

High frequency ventilation (HFV) has been used for the last two decades. Several questions related to its optimal use, comparative efficacy of different types of HFV, as well as the role of HFV in different diseases are still debated and under investigation. Literature reviews discussing the controversies in high frequency ventilation have rather emphasized the importance of a disease strategy rather then the type of HFV. In this article, a presentation and discussion of five patients with different HFV strategies admitted and managed with HFV at the American University of Beirut-Medical Center.

Female↗

PubMed1980

Inhibition by estradiol of human chorionic gonadotropin-induced progesterone accumulation in isolated human luteal cells: lack of mediation by prostaglandin F.

Estradiol has been previously reported to be a potent inhibitor of hCG-stimulated progesterone accumulation in isolated cells from human corpora lutea of the menstrual cycle. We assessed the role of prostaglandin (PG) in this in vitro estradiol-induced inhibition by measuring PGF and adding a blocker of PG synthesis (indomethacin) to the incubation medium. The inhibition by estradiol of hCG-stimulated progesterone accumulation occurred without any increase in PGF accumulation in the incubations. Furthermore, PGF accumulation was markedly reduced (P less than 0.05) at all concentrations of indomethacin testes (0.1, 1, and 10 microgram/ml), but the inhibitory effect of estradiol on hCG-stimulated progesterone accumulation was not prevented. These data suggest that the inhibitory effect of estradiol observed in vitro is not mediated by PGs.

Adult↗