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Biomedical subjects

N Zachariades

Publications and source records attributed to N Zachariades.

At least 55 records · Page 3Linked to original sources

Recurrences of ameloblastoma in bone grafts. Report of 4 cases.

4 cases of recurrent ameloblastomas in bone grafts are reported. 1 case was treated with freeze-dried homogenous bone chips and the others with solid autogenous, iliac or rib grafts. The interval between the initial operation and the recurrence in the bone graft ranged from 2 to 36 years.

Adult↗

Juvenile fibromatosis.

Fibromatosis is an aggressive, non-metastasizing disease characterized by a neoplastic proliferation of fibroblasts, that rarely involves bone and lies on the borderline between benign and malignant tumours. We report three new cases of this rare entity.

Child↗

Traumatic carotid-cavernous sinus fistula.

Traumatic carotid-cavernous sinus fistula is an uncommon situation resulting from severe trauma, with less than 40 cases having been reported. It is usually associated with a skull base, frontal or mid-facial fracture, but it may also be a spontaneous phenomenon of congenital, infective or degenerative origin. The blood shunts from the internal carotid to the cavernous sinus resulting in pulsating exophthalmos, orbital headache, pain, orbital or frontal bruit, loss of visual acuity, diplopia, ophthalmoplegia and the differential diagnosis should include superior orbital fissure syndrome, orbital apex syndrome and cavernous sinus thrombosis. Several modes of treatment have been proposed. We were recently faced with such a case, who had sustained fractures of the facial skeleton and developed the fistula despite an initial non-contributory angiogram. The patient remained in a permanent coma.

Accidents, Traffic↗

Malignant fibrous histiocytoma. Review of the literature and report of a case in a four-year-old child.

A case of fibrous histiocytoma is presented, originally diagnosed as aggressive, which eventually ran the course of fibrosarcoma. We feel that when dealing with any form of "fibromas" one must be very careful as far as the diagnosis and the prognosis are concerned, because there are no clear histological and clinical borders between the benign and malignant counterparts. A wide excision is required in most of the cases, if a recurrence is to be avoided, and a close follow-up to detect any metastasis. The term "aggressive" used in many such lesions could be a convenience in the face of inability to better describe the tumor, and inaccuracy should rather turn our attention towards the malignant side.

Child, Preschool↗

Emphysema and similar situations in and around the maxillo-facial region.

The introduction of air into the soft tissues surrounding the maxillofacial region is the subject of this report. We present seven cases varying from emphysema following dental manipulation, severe facial trauma, with and without clinical or radiographic evidence of fracture, to a case that resulted in blindness and another case that required emergency tracheostomy. We propose the modification of the term emphysema so as to include the entry of air into the brain by the same mechanism.

Adult↗

Fracture of the hyoid bone--report of a case.

The hyoid bone, well protected under the protruding chin, seldom sustains fractures in road traffic accidents. We report such a case and review 14 cases found in the world literature.

Adolescent↗

Benign neurogenic tumors of the oral cavity.

Neurogenic tumors are rare in the oral cavity, particularly so when malignant. Traumatic neuroma, although usually included with neurogenic tumors, is a reactive process rather than a true neoplasm. Neurofibroma and schwannoma derive from nerve fibers, the perineurium, the endoneurium and the neurolemmomal cells. They present histological differences. The neurofibroma may present in solitary and generalized types; the latter also known as neurofibromatosis or von Recklinghausen's disease of the skin. We here report typical cases of benign neurogenic tumors of the oral cavity.

Aged↗

Orbital apex syndrome.

The orbital apex syndrome is a very rare complication of fractures of the facial skeleton, as well as other conditions and is characterized by blindness, fixed dilated pupils, proptosis, ptosis of the eye and ophthalmoplegia. We are reporting such a case we had the opportunity of treating.

Blepharoptosis↗

Uncommon manifestations of histiocytosis X.

Histiocytosis X is a group of disorders of uncertain etiology with a variety of manifestations that are usually related to the age of the patient. Treatment consists of local curettage, irradiation and chemotherapy. The prognosis depends on the systems involved. The oral and perioral tissues are occasionally involved and often lead to the diagnosis. We report a case with spinal cord involvement and a case of facial nerve paralysis secondary to involvement of the petrosal bone. Also included is a case of involvement of the mandibular condyle.

Bone Diseases↗

Chondrosarcoma of the orofacial region. Review of the literature and report of two cases.

Chondrosarcoma of the jaws arises from vestigial rests and is considered a rare entity, although it is more common than its benign counterpart. Occasionally it may be extremely difficult under the microscope to decide whether a case is benign or malignant. The treatment of choice is surgical with wide margins. In our review of the literature we found 169 cases of oro-facial chondrosarcoma including two from our Institution. There was a 2:1 male/female ratio and the maxilla was involved twice as frequently as the mandible. Over half of the cases were between 20 and 50 years old.

Adult↗