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Biomedical subjects

N Zachariades

Publications and source records attributed to N Zachariades.

At least 19 recordsLinked to original sources

Changing trends in the treatment of zygomaticomaxillary complex fractures: a 12-year evaluation of methods used.

PURPOSE: The efficacy of the current methods for the treatment of fractures of the zygomaticomaxillary complex was evaluated. PATIENTS AND METHODS: One thousand two hundred seventy-seven patients with fracture of the zygomaticomaxillary complex and 196 patients with fractures of the zygomatic arch that were admitted between 1984 and 1995 were evaluated. One thousand one hundred fifty surgical procedures were performed, and in 401 cases, no operative treatment was considered necessary. The Gillie's approach was used in 514 cases, intraosseous wiring in 89 cases, bone plate osteosynthesis in 322 cases, Roger-Anderson pins in 180 cases, antral packing in 17 cases, and elevation with a hook in 28 cases. RESULTS: The best results were achieved with the use of semirigid fixation with miniplates applied at one or more sites of the fractured complex, occasionally used in combination with other methods such as Roger-Anderson pins. CONCLUSIONS: Semirigid fixation with miniplates offers the most reliable method available today for the treatment of zygomatico-orbital complex fractures and has practically replaced every other method in our institution. The increased cost and occasionally the necessity to remove the hardware are the main disadvantages of the method.

Bone Nails↗

Blindness after facial trauma.

Blindness after facial fractures has been reported to occur with an incidence that ranges between 0.67% and 3% depending on the reporting institution. To verify this finding we undertook a retrospective chart review of 5936 patients with facial fractures that occurred over a 12 1/2-year period. We found that vision in 19 eyes were lost in 18 patients. Vision loss was more frequently encountered in Le Fort III level fractures (2.2%) followed distantly by Le Fort II level fractures (0.64%), and zygomatic fractures (0.45%). The cause of blindness was most frequently associated with motor vehicle accidents and gunshot injuries. Injuries of this type require immediate and prompt consultation by the ophthalmologic surgery service.

Accidents, Traffic↗

Use of lag screws for the management of mandibular trauma.

OBJECTIVE: To test the effectiveness of lag screw fixation in their application in the treatment of mandibular fractures. MATERIAL AND METHODS: Sixty-nine mandibular fractures in 30 patients treated with lag screws were evaluated retrospectively regarding the cause, the type, and the site of fracture as well as the local situation and the complications encountered. RESULTS: In 19 fractures a neutralization plate was used and in another 17 the lag screw was applied in combination with a compression plate. In 33 cases at least 3 lag screws were inserted. Seventy-five percent of the cases were in patients between 10 and 39 years old; 70% were the result of road traffic accidents. Most patients presented two mandibular fractures; the symphyseal area were most frequently affected. Teeth in the line of fracture were not removed, and no drains were used. Complications included two minor malocclusions, one delayed union, two cases of temporary paresis, two cases of transient hypesthesia, two cases of scar formation on the incision line, and a case of temporary trismus. CONCLUSIONS: Approximately 30% of the patients treated with lag screws according to the methods outlined in this study developed complications that were either minor, transient, or both; some were related to the approach rather than the method. The most frequent complications were minor malocclusions, transient facial paralysis, hypoesthesia, and scar formation.

Accidents, Traffic↗

Complications of treatment of mandibular fractures with compression plates.

A total of 320 mandibular fractures with maxillomandibular fixation under local anesthesia were treated in this study. From this group, 244 fractures were treated with compression osteosynthesis. The complication rate was 13%; several patients had more than one complication. The complication rate decreased with the increase of operator experience. Malunions were recorded in 3.6% of the cases (1% in single and 7.5% in multiple fractures). Comminution, delay in treatment, and gross displacement were some of the factors related to malunion. The infection rate varied from 1% for those treated within the first week to 4% for those treated after at-least 2 weeks after the accident. Except for the delay in treatment, poor local conditions were a predisposing factor for infection. No infection was recorded in cases treated intraorally.

Adult↗

Squamous cell carcinoma developing in an odontogenic keratocyst.

A case of squamous cell carcinoma arising in an odontogenic keratocyst is presented. Although the patient was treated by wide local excision of the tumor, with radical neck dissection, and although the regional lymph nodes were free of metastatic deposits, the carcinoma recurred locally two months later and the patient died two years after the first operation with pulmonary metastases.

Aged↗

Adult-type of rhabdomyoma of the cheek. A case report with emphasis on the histological and immunohistochemical features.

A case of adult-type rhabdomyoma of the cheek is reported. The tumor was composed of cells presenting striated muscle differentiation, which was confirmed immunohistochemically by the positive reaction with alpha 1-sarcomeric actin demonstrating the cytoplasmic cross striations. A careful evaluation of the light microscopic features of this rare tumor, as well as the histochemical and immunohistochemical characteristics of the tumor cells would greatly help the differential diagnosis.

Humans↗