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Biomedical subjects

N Younis

Publications and source records attributed to N Younis.

At least 37 records · Page 2Linked to original sources
PubMed1993

Concepts and measures of reproductive morbidity.

This paper presents a conceptual and methodological framework developed by an interdisciplinary group of researchers to diagnose reproductive morbidity at the community level. The paper also presents a determinants structure that delineates the health and social factors hypothesized to influence reproductive morbidity. The high prevalence of reproductive-morbidity conditions revealed by implementation of the study framework in two villages of Giza in Egypt is reported. Based on this research experience and the process of presenting its results to the larger professional community, the paper discusses policy implications of the study in terms of reproductive-health services, education and training programs and research efforts for measurement of reproductive ill-health at a community setting.

Adolescent↗
PubMed1988

On the solubility of calcium deoxycholate: kinetics of precipitation and the effect of conjugated bile salts and lecithin.

In view of the low solubility of calcium deoxycholate and the possible induction of cholesterol precipitation in the gallbladder by calcium insoluble salts, we find it of interest to study the precipitation of calcium deoxycholate and its dependence on other bile components. The findings of these studies were as follows: (i) Precipitation of calcium deoxycholate from mixtures of calcium chloride and monomeric deoxycholate (at concentrations below the critical micelle concentration (CMC] is very slow even at relatively high CaCl2 concentrations (more than 20 days at 50 mM CaCl2). (ii) At higher deoxycholic acid (DOC) concentrations, precipitation of micellar DOC is faster and requires much lower calcium chloride concentrations. For any given calcium concentration, the rate of precipitation is maximal at an optimal DOC concentration. In solutions containing 150 mM NaCl, the maximal rate of precipitation occurs at about 10 mM DOC, almost independent of Ca2+ concentration. At lower ionic strength (10 mM NaCl), the optimal DOC concentration is 30 mM. These observations suggest that the most important factors in determining the rate of Ca(DOC)2 precipitation are (a) the ratio between calcium ions bound to the surface of a DOC micelle, and the [DOC] (the Ca2+/DOC binding ratio) and (b) the concentration of DOC micelles. (iii) In the presence of conjugated deoxycholates, the crystallization of calcium deoxycholate is inhibited. Phosphatidylcholine has a similar, although smaller, inhibitory effect. Upon precipitation of calcium deoxycholate from a mixed micellar system containing sodium deoxycholate, phosphatidylcholine and cholesterol, the latter two components spontaneously form vesicles. The anti-nucleating effect of PC and conjugated bile salts is explained in terms of "poisoning" of the crystallization process. In view of the latter results we conclude that under normal conditions calcium deoxycholate is not likely to precipitate in the gallbladder.

Bile Acids and Salts↗
PubMed1983

Peranal sleeve anastomosis for low rectal cancer.

Over a 3-yr period, 13 patients underwent surgery for a rectal tumor located between 5 and 7 cm from the anal verge. We modified Parks' procedure for a peranal sleeve anastomosis in order to avoid tension and retraction. Until now, the preferred operation for tumors at this location was abdominoperineal excision as devised by Miles. In the light of present-day knowledge, some of the lesions situated at a slightly lower level in the midrectum can be treated with a less mutilating surgical approach which is associated with continence and satisfactory sphincter function. There was no postoperative mortality. During a 5-yr follow-up period, 2 of the 13 patients died; there was no recurrence of local tumors.

Abscess↗
PubMed1982

Laparoscopic ventrosuspension: a new technique.

During 42 months of study, 150 cases of laparoscopic ventrosuspension were performed at Al-Azhar University hospitals. In 98 patients (65.33%), the primary complaint was infertility. Retroversion of the uterus was the only abnormality detected during laparoscopic examinations. The remaining 52 patients (34.66%) had retroversion of the uterus concomitant with other conditions requiring surgery. Ventrosuspension was performed via the laparoscope by applying Falope rings (KLI, Newtown, Pennsylvania USA) to the round ligaments. These patients were followed up for 6-30 months. Pregnancy occurred in 29 infertile patients and improvement of backache, deep dyspareunia, congestive dysmenorrhea and leukorrhea occurred in 81.25%, 89.25%, 68.18% and 56.66%, respectively. The technique is simple and safe; it reduces the length of hospitalization and can be performed concomitant with other surgical procedures.

Female↗
PubMed1982

Laparoscopy on patients with previous lower abdominal surgery: a new technique.

During the period June 1979--May 1981, 1582 diagnostic and operative laparoscopic procedures were performed at Al-Azhar University Endoscopy Unit and during field visits to several hospitals in Egypt, Sudan and Mauritania. Ninety-nine of these had had previous lower abdominal surgery. Laparoscopy was performed on 93 of these patients using a modified technique of laparoscopy. The modified technique involves direct visualization of the previous peritoneal scar with the scope before its careful puncturing with the trocar and cannula. The paper describes the technique, findings, complications, limitations of the procedure and its application.

Abdomen↗
PubMed1981

Pregnancy wastage.

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Abortion, Spontaneous↗
PubMed1977

The benefit of lactation amenorrhea as a contraceptive.

A group of 148 lactating women who delivered normally at El-Galaa Hospital, Cairo, were followed up monthly for 1 year to study the pattern of lactation amenorrhea, the return of menstruation and ovulation, and the incidence of pregnancy. By the end of the sixth week postpartum, only 1.3 percent of the women had begun menstruating; the percentage gradually increased to 60.2 percent by the end of the first year. The amount of blood loss and the duration of menstruation increased gradually until the fourth postpartum menstrual period. Ovulation had occurred in 58.1 percent and pregnancy in 26.1 percent of all cases at the end of the 12th postpartum month. Among menstruating, lactating mothers, ovulation occurred in 86.5 percent and pregnancy in 32.6 percent, while in amenorrheic, lactating mothers only 6.1 percent had become pregnant at 1 year postpartum.

Amenorrhea↗