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Biomedical subjects

N Yoshii

Publications and source records attributed to N Yoshii.

At least 37 records · Page 2Linked to original sources

Long-term follow-up study after pulvinotomy for intractable pain.

Pulvinotomy was performed on 42 cases with intractable pain. 19 cases survived for more than 1 year, the results were classified as follows: 4 were excellent, 4 good, 5 fair, and 4 were poor. The effects of the operation are discussed based on the disease. 2 cases, who survived for more than 1 year, suffered from the pain due to infiltration or metastasis of cancer, they died 22 and 14 months after the operation, respectively, but they had no intractable pain during the year before death. 14 cases who underwent CVD survived for more than 1 year. Results of the operation were as follows: 3 were excellent; 4 good, 4 fair, and 4 were poor. These cases were followed up for 3-10 years and the average was about 5 years. After more than 1 year, 2 cases with atypical facial pain were considered as being either fair or poor, one (fair case) of whom still does routine housework and is not drug dependent. A case of causalgia has been free from pain for 5 years after the operation.

Adolescent↗

Hypothalamic projection to the pulvinar-LP complex in the cat: a study by the silver impregnation method.

This study was designated to determine the exact terminal portion of the hypothalamo-thalamic projection found in our previous study by the HRP method [7]. Electrolytic lesions were made in the brains of 13 adult cats, and the ensuing degenerating fibers were impregnated with Nauta-Gygax and Fink-Heimer methods. Following the lesions of the hypothalamic small nucleus which had been reported to receive abundant HRP transport from the pulvinar-LP complex, terminal degeneration concentrated in the dorsolateral marginal area of LP, forming a well-defined and dorsomedially stretched slim column along the medial border of the pulvinar. The level of its appearance approximately corresponds with the stereotaxic coronal plane, Fr. 7.0. In the contralateral same thalamic area the degenerating fibers were also traced though they were much fewer.

Animals↗

Effects of unilateral and bilateral invasion of thalamic pulvinar for pain relief.

Thalamic pulvinotomy has been performed on 32 patients in severe chronic pain and a follow-up study was made. Among 10 patients with whom unilateral invasion was made, 4 were "excellent" in relieving pain, 2 "good", 2 "fair" and 2 "poor". Among 22 cases of bilateral invasion 17 were "excellent", 2 were "good", and 3 were "poor". Thus, in the cases of bilateral invasion effects of the operation were more prominent than in the cases of unilateral invasion. Further, transient psychic symptoms following the operation has been analysed in relation to position of pulvinar destruction and to underlying diseases.

Adolescent↗

Significance of pathognomonic features of normal-pressure hydrocephalus on computerized tomography.

In some patients with congenital or acquired hydrocephalus, a low-density area is seen around the lateral ventricle on computerized tomography. Above all, in patients with normal-pressure hydrocephalus following subarachnoid hemorrhage, there appears a specific low-density area which is fan-shaped and irregular and which extends from the bilateral anterior horns to the frontal pole. This disappears or decreases with a VP shunt. Improvement of clinical symptoms is proportional to the degree of disappearance of the low-density area. The essential part of the occurrence of symptoms in patients with normal-pressure hydrocephalus depends upon a low-density area on CT.

Brain Neoplasms↗

Posttraumatic epilepsy and CT scan.

Among 83 head-trauma cases examined by CT scan in a later year, 41 were included in a seizure group of those who clinically showed late epilepsy and who obviously showed epileptic discharge such as spike or spike and wave in EEG after trauma, and 42 were included in a nonseizure group of those who had some sequelae such as abnormal findings in EEG or neurologic defects: the CT findings of these 83 cases were collected and compared with clinical findings, EEG, and other data. The CT findings of these cases were divided into five groups: (A) a normal group; (B) a group showing partial or unilateral ventricular dilatation; (C) a group showing porencephaly in the cerebral parenchyma; (D) a group suspected of cortical atrophy; (E) a group of other cases. Group D contained 44.3% of the cases, and was the largest group; the frequency of seizure was highest in Group C. The CT classification reveals the contradiction of the conventional definition of posttraumatic epilepsy and also poses some problems concerning the disease. CT scan is mostly applied to head trauma in the acute stage, and as for trauma in the chronic stage there are a few reports on chronic subdural hematoma and post-traumatic hydrocephalus. We noticed posttraumatic epilepsy among the sequelae of trauma, and then analyzed CT findings of the epilepsy: the results are reported here.

Adolescent↗