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Biomedical subjects

N Yamaguchi

Publications and source records attributed to N Yamaguchi.

At least 685 records · Page 38Linked to original sources
PubMed1988

Plain chest radiograph with computed radiography: improved sensitivity for the detection of coronary artery calcification.

The ability of computed radiography (CR) with photostimulable phosphor to detect coronary artery calcification (CAC) was compared with conventional radiography with the film-screen method. Posteroanterior and lateral chest radiographs were reviewed that had been obtained with both methods in 77 patients with a variety of heart diseases. Cineangiography confirmed that 31 patients had CAC (left CAC in 31 patients, right CAC in 11) and that 46 patients had no CAC. For left CAC, the sensitivity of CR was 71%, significantly higher than that of conventional radiography (32%, p less than .01). For right CAC, the sensitivity of CR was only 27%, but that of conventional radiography was 0%. The specificities in detecting CAC were similar for both methods (CR, 96%; conventional method, 100%). Fine anatomic details of calcified foci were seen more clearly on CR. Chest imaging with the CR system is a promising method for detecting CAC.

Adolescent↗
PubMed1988

Congenital middle and inner ear anomalies.

For this study, 100 human temporal bones from 73 individuals, aged 31 gestational weeks to 39 years, each with anomalies of the middle and/or inner ear, were studied to identify the features, locations, and frequencies with which congenital anomalies occurred in these structures. The temporal bones had been removed at autopsy, fixed, dehydrated, embedded in celloidin, sectioned horizontally or vertically at 20 microns, stained with hematoxylin and eosin, and studied under a light microscope. The anomaly in the middle ear most often found was wide dehiscence of the facial canal; hypoplastic cochlea was most frequently observed anomaly in the inner ear. The implications of these findings for development of the ear during fetal life are discussed.

Ear, Inner↗
PubMed1988

[Evaluation of postoperative hepatobiliary function by deconvolution analysis of hepatobiliary image data by 99mTc-N-pyridoxyl-5-methyltryptophan].

Dynamic hepatobiliary image data were analyzed by the mathematical deconvolution to derive the transfer function (TF) which represents the impulse response function of the liver following direct bolus injection of a tracer into the liver. Biliary flow was evaluated by TF in patients with previous hepatobiliary surgery to detect abnormal flow causing problems such as cholangitis. Serial image data were collected for 60 min after intravenous injection of 37-75 MBq (1-2 mCi) of 99mTc-N-pyridoxyl-5-methyltryptophan (99mTc-PMT). TF was obtained by the matrix algorithm, using regional hepatogram as output and time-activity curve over the heart as input function. Minimum, mean and maximum transit time (Max. TT) were determined from TF. The functional image for each of the transit times was constructed by displaying the distribution of the values for matrix elements with a color scale. In this study, a critical Max. TT of 60 min was used to detect abnormal biliary flow. Of 30 cases, 9 positive cases were discriminated from 21 negative cases on the basis of the finding of presence or absence of areas with Max. TT of more than 60 min anywhere in the liver. Bowel activity overlapping the liver was excluded in the judgment. The validity of this method was evaluated in comparison with the clinical courses after surgery with (8 cases) or without (22 cases) problems. The results were sensitivity of 88%, specificity of 91%, accuracy of 90% and positive predictive value of 78%.(ABSTRACT TRUNCATED AT 250 WORDS)

Aged↗
PubMed1988

[Continuous superselective intra-arterial infusion with BUdR and 5 FU in combination with radiotherapy in the treatment of head and neck tumors].

Since 1984, a new method for intra-arterial administration of anti-cancer drug and radiosensitizer, named 'superselective continuous intra-arterial infusion therapy' has been used in combination with simultaneous irradiation, for the treatment of 67 patients with the head and neck tumors. Under fluoroscopy, a preshaped catheter was introduced retrogradely from the superficial temporal artery and inserted superselectively into the main feeding artery of the tumor. Through this catheter, continuous intra-arterial infusion chemotherapy was done. The primary therapeutic effects were appreciated as complete or partial response in all cases. It was considered that this method was more effective and with less adverse reactions for the treatment of the head and neck tumors compared with the conventional method.

Bromodeoxyuridine↗