Cell-mediated cytotoxicity against skin fibroblasts in atopic dermatitis.
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Biomedical subjects
Publications and source records attributed to N Wood.
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Materials believed to be hydroxyacyl-ceramides (HO-Cer) and hydroxyacyl-cerebrosides (HO-Ceb) have been analyzed by high performance liquid chromatography (HPLC) from the glycolipid components of six female rhesus monkey gingivae. These recovered materials show identical behavior by (HPLC) with authentic standards.
Total fucose and protein was measured in gingival fluid samples collected from 16 human subjects. A significantly higher total protein concentration was found for the control (clinically normal) group when compared to the experimental (severe clinical inflammation) group. This is probably due to the higher gingival flow rate found in the experimental group. The total fucose analyses showed no statistical difference between both groups, but when fucose to protein ratios were studied, a significantly higher ratio was found for the experimental group when compared to the controls. This probably represents the breakdown of plasma and tissue glycoproteins which may occur as a result of inflammation.
Acetylcholinesterase (AChE) activity in homogenates from motor and visual cortex of rats reared for 7 weeks in darkness was compared to levels in normally reared and dark reared littermates exposed to 3-h periods of controlled illumination. AChE levels in the visual cortex of animals fitted with light-diffusing scleral contact occluders, and therefore lacking normally organized visual information, were elevated 17% over dark-reared animals, but were not significantly different from levels in animals exposed to lighting conditions permitting detailed pattern discrimination. There were no differences between conditions in motor cortex AChE. We conclude that higher order perceptual processing is not necessary for the light-stimulated increase in visual cortex AChE in the rat.
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