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Biomedical subjects

N Wolf

Publications and source records attributed to N Wolf.

At least 73 records · Page 4Linked to original sources
PubMed1983

Segregation of germline granules in early embryos of Caenorhabditis elegans: an electron microscopic analysis.

Using an improved fixation method for electron microscopy, we have found germline granules in Caenorhabditis elegans embryos shortly after fertilization and prior to the first cleavage. They are localized in the egg cytoplasm which becomes segregated into the posterior blastomere at the first cleavage. In the following divisions, the granules continue this pattern of asymmetric segregation and are ultimately segregated into the germline precursor cell. The granules are then symmetrically segregated into the germline cells.

Animals↗
PubMed1982

Distribution and identity of the earliest proliferating progeny of colony-forming cells in regenerating murine spleen and bone marrow.

A study was made of the sites of development and the types of cells found in very early hemopoietic colonies in the mouse spleen. Two, 3, and 4 days after transplantation, the proliferating descendants of transplanted bone-marrow cells were identified on radioautographs of spleen sections and on spleen and bone-marrow smears of supralethally irradiated recipient mice which were injected with 3H-TdR at 12, 6, and 0.5 hours before sacrifice. Surprisingly the spleens of nontransplanted, irradiated mice contained proliferating medium and large lymphocytes in the white pulp which increased in numbers during the observation period. The early descendants of transplanted cells that lodged in the spleen could be clearly distinguished from the labeled indigenous cells because they formed discrete nodules or colonies beneath the splenic capsule or in the vicinity of venules and trabeculae of the red pulp. These cells were identifiable on day 2 as transitional cells or unknown hemopoietic blasts and on day 4 included early erythroid cells and small lymphocytes. There was evidence for the traffic of 3H-TdR-labeled cells through the splenic sinusoids.

Animals↗
PubMed1982

[Localization diagnosis and differential diagnosis of postoperative intraperitoneal abscesses using 99m technetium-stannum-colloid-marked granulocytes].

Occult intraperitoneal abscesses are difficult to locate and dispose of. Therefore, a method of examination is needed that is specific, can be used at any time, is not expensive, and yields early results within 2-3 h. This seems possible with a new methods of examination. 99mTc-Sn colloid was used to label autologous polymorphonuclear leukocytes which, when reinjected, emigrate to the site of the suspected abscess. Standard scintigraphy localizes the labeled inflammatory cells. In 32 surgical patients, 34 scans were performed with good results (controlled by greyscale ultrasound); 17 (53.1%) scans represented intraperitoneal abscesses; 3 (9.4%) scans demonstrated true positive extra-abdominal inflammations.

Abscess↗
PubMed1981

[Transplantation of nervus peroneus by microsurgery (author's transl)].

From 1969-1977 at the Erlangen University Surgical Clinic 15 transplantations of the nervus peroneus were performed. 10 patients could be followed up within a time of 2-5 years after operation. As to the sensibility in most cases only protective sensibility could be achieved; as to the motor function the results were likewise poorer than in the upper limb. Beside our own results those of other authors were reported. Possible causes of the relatively bad prognosis of the Nervus peroneus were shown.

Accidents↗
PubMed1977

An epidemiological study of haemoglobin levels in infancy in Jerusalem. The effect of social factors and the relation to physical growth.

The infant population of a mixed middle and low social class community in a western neighbourhood of Jerusalem has been examined for haemoglobin, haematocrit weight and length at 9 months of age. The mean haemoglobin has been 11.1 g/100 ml, the mean haematocrit 36.1 and the mean MCHC 31.1%. In most cases the anemia has been mild. Statistically significant differences in the mean haemoglobin have been found by social class of father and sex of the child. No statistically significant association has been found between birth weight, weight and length at 9 months and mean weight increment per week between birth and 9 months of age and haemoglobin. Lower levels of Hb have been demonstrated in the males by categories of birth weight and categories of weight increment.

Anemia↗
PubMed1975

[Drawings of young drug addicts].

Due to addiction being a complex process of illness, there are no available designatory aspects facilitating the pictorial illustration of addiction. To appreciate pictures of young drug addicts, therefore, it is necessary to know in which stadium of the addiction process (intoxication or treatment stadium, or detachment phase) the pictures were taken; when the addiction began (prior to, in the course of, or after completion of puberty), and how long the addiction is pertinent. Pictorial depictions of a 22- and a 17-year-old man, as also of a 15-year-old girl, who are polytoxicomane, and who were in the detachment phase, are demonstrated. The common quality of these pictures is to be noted in the earnestness with which these young people endeavour to recognise the problems of their lives (e.g., the threat to their inner existence); the confrontation of the so-called problemless world versus the problematic drugs world, and to express this pictorially.

Adolescent↗