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Biomedical subjects

N Wells

Publications and source records attributed to N Wells.

43 records · Page 3Linked to original sources
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Past, present, and future directions for Alzheimer research.

To understand the current thinking and future research directions in Alzheimer disease (AD), it is essential to examine the breadth of research into AD. AD was identified as a distinct disease process early in this century and research into its etiology and treatment has a short, but active, history. This paper emphasizes past, present, and future biomedical research for the goal of stimulating research to solve some of the unanswered questions to ultimately help the victims of Alzheimer disease. The "hot" topics today for biomedical researchers include early diagnosis, presymptomatic markers, the role of presenilins, amyloid, protein precursor processing, and continued exploration for genetic and environmental risk factors.

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Nursing research and solving problems of Alzheimer disease.

This article discusses the applied science of the nursing discipline and nursing issues related to Alzheimer disease. Three models are presented and illustrated with interdisciplinary research ideas to improve the care of persons who suffer from dementia of the Alzheimer type (DAT). Phases of Nursing Research is a five-component model to (1) identify problems, (2) conduct the study, (3) disseminate results, (4) utilize findings that are to the central component, (5) practical knowledge. Promoting evidence-based care for making a recommendation against artificial feeding and providing the tools to promote natural feeding illustrates the Interdisciplinary Collaboration model. The Program of Research model is described by studies of late-stage DAT, intercurrent infections, and decision making. Issues framing nursing research are discussed and specific suggestions for research projects developed from recent funding priorities of the National Institutes of Health are given.

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Structure and process of federal funding for AD research.

This paper outlines the structure of the National Institute on Aging (NIA), the National Institutes of Health (NIH) agency that funds a majority of Alzheimer disease (AD) research, and the process of submitting a federal grant application. The multiple steps of the grant application process, both for the investigator preparing the application and the review process at NIH, are described. The importance of speaking with a program officer from an institute and incorporating reviewers' comments into grant applications to strengthen the proposal is stressed.

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Idea to application: you are in charge.

The grant writing process can be daunting to a novice investigator. This article focuses on three inter-related activities that lead to a completed grant application. The first activity involves developing the research team. Selection of colleagues who will strengthen and support the research ideas is an early first step to developing a competitive grant application. It is important to communicate clearly the roles and responsibilities of each team member. The second activity is development of the scientific plan-the research proposal-from specific aims to plans for data analysis. Strategies used to review the literature, synthesize existing knowledge, develop the argument for the research proposal, and select the most appropriate method are discussed. The third activity involves developing a business plan-the budget-that demonstrates clearly the investigator's ability to complete the proposed research. These three activities are set within a timeline to guide investigators in successful completion of a grant application.

Job Application↗
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The grant application: making yours stand out across the review cycle.

This article provides an overview of the grant application during the review process. Three levels of review occur once a grant is submitted-administrative, scientific, and programmatic. The purposes of each level of review are different, but the overall goal for the funding agency is to fund grant applications that address important research topics, are scientifically meritorious, and assist the agency in meeting their goals and objectives.

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The effect of relaxation on postoperative muscle tension and pain.

Relaxation training has been postulated to decrease abdominal muscle tension, a source of postoperative pain, as well as alter the psychological variables of anxiety and perceived control. A two-group pre- and posttest experimental design was used to determine if abdominal muscle tension, self-report of pain and distress differ in adult cholecystectomy patients in two treatment conditions. Six patients received relaxation training, and six patients, serving as a control, received standard preoperative instruction. Results showed the distress caused by painful sensations was lower for patients who learned the relaxation technique.

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